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The map label for this gene is era [H]

Identifier: 113476532

GI number: 113476532

Start: 4596040

End: 4596972

Strand: Reverse

Name: era [H]

Synonym: Tery_2959

Alternate gene names: 113476532

Gene position: 4596972-4596040 (Counterclockwise)

Preceding gene: 113476534

Following gene: 113476531

Centisome position: 59.31

GC content: 38.26

Gene sequence:

>933_bases
ATGGAATTGTCCACGAATATAACTATTCCCGTAGCACCTGCGGGGTATAAATCAGGGTTTGTTGGCATAATAGGACGACC
CAATGTTGGAAAATCTACTTTGATGAATCAACTAGTGGGGCAAAAAGTTGCTATTACCTCCCCAGTTGCTCAAACTACTC
GTAATCGTCTGCGTGGTATTTTGACTACACAAGCAGCTCAGATAATTTTTGTTGATACCCCAGGTATTCATAAGCCTCAG
CACCAACTAGGAAAAGTATTAGTTCAAAATGCTAAAGTAGCAATTCAATCTGTAGATTTAGTTTTGCTGATAGTAGATGG
ATCAGTAATAGCAGGTGGAGGCGATCGCTATATTATAAATTTACTGGATAAAATCCAAACTCCTGTAATTTTAGGTATGA
ATAAATTAGACCTACAACCTCAAGATGCTTGGAAAATAGAAGCTAGTTATTATCAATTAATCCATCCTCACCCCTGGCAA
ATAATCAAATTTTCTGCTGTCACAGGAGAAGGAGTAGAAATACTACAAGATTTATTGATTGAACAGATGGAAACTGGACC
TTATTATTATCCTCCTGATTTAGTAACAGACCAAGCAGAACGCTTTATTATGGGGGAGCTGATCCGGGAGCAAATTTTAT
TGTTGACTCGTGAGGAAGTACCCCACTCAGTAGCGATTGCTATTGACAGAGTAGATGAAGAACCAACTATTACTCGTATT
CTTGCCACTATTAATGTGGAACGTTCATCTCAAAAAGGAATTCTAATTGGTAAGGGTGGGAATATGTTAAAAGCTATTGG
TAGTGCGGCACGTCAACAAATTCAAAAGTTAATTGCAGGTAAGGTGTATTTGGAGCTATTTGTAAGAGTACAGTCTAAAT
GGCGACAGTCTCGAATTCAGTTAGCTGAGTTAGGATATCAGGTTGAAGAATGA

Upstream 100 bases:

>100_bases
TCAGTAGACGCTGTTGCTTTCTTAGACTCCTGTTTTTCCTATCAAGAATTTTGACTTTATCAGCTATTATCTAGGAAACA
AAAGTTAAAAAAATCTCAAA

Downstream 100 bases:

>100_bases
AAAAAACTTTATTAGATTTTAATAGAGCAGGACTGACACAAAGACACTATATATCGCTTATGATAATTCAGATGATATTT
ACGCTTTGCTTTATGCGCGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGILTTQAAQIIFVDTPGIHKPQ
HQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIINLLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQ
IIKFSAVTGEGVEILQDLLIEQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRI
LATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQLAELGYQVEE

Sequences:

>Translated_310_residues
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGILTTQAAQIIFVDTPGIHKPQ
HQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIINLLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQ
IIKFSAVTGEGVEILQDLLIEQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRI
LATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQLAELGYQVEE
>Mature_310_residues
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGILTTQAAQIIFVDTPGIHKPQ
HQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIINLLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQ
IIKFSAVTGEGVEILQDLLIEQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRI
LATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQLAELGYQVEE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=337, Percent_Identity=27.5964391691395, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788919, Length=291, Percent_Identity=37.4570446735395, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI2367268, Length=166, Percent_Identity=31.3253012048193, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=31.3253012048193, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34298; Mature: 34298

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGI
CCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
LTTQAAQIIFVDTPGIHKPQHQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIIN
HEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCEEECCCCHHHHH
LLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQIIKFSAVTGEGVEILQDLLI
HHHHHCCCEEECCCCCCCCCCCCEEEEECCEEEECCCCCEEEEEEECCCCHHHHHHHHHH
EQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHE
LATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQ
EEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELGYQVEE
HHHCCCCCCC
>Mature Secondary Structure
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGI
CCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
LTTQAAQIIFVDTPGIHKPQHQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIIN
HEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCEEECCCCHHHHH
LLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQIIKFSAVTGEGVEILQDLLI
HHHHHCCCEEECCCCCCCCCCCCEEEEECCEEEECCCCCEEEEEEECCCCHHHHHHHHHH
EQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHE
LATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQ
EEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELGYQVEE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]