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The map label for this gene is eno

Identifier: 113476382

GI number: 113476382

Start: 4330341

End: 4331627

Strand: Reverse

Name: eno

Synonym: Tery_2793

Alternate gene names: 113476382

Gene position: 4331627-4330341 (Counterclockwise)

Preceding gene: 113476384

Following gene: 113476378

Centisome position: 55.89

GC content: 41.41

Gene sequence:

>1287_bases
ATGGAGACAGCTATTGAATCAATTCAGGCTAGAGAAATTCTTGATTCTCGTGGTCGTCCAACCGTGGAAGCAGAAGTCCA
CCTAGTTAATGGGAGCATGGGATTGGCCCAAGTGCCCAGTGGTGCATCAACAGGTAGCTTTGAAGCTCATGAACTTCGGG
ATGGAGACAAAGGACGCTATAGTGGCAAAGGGGTACTCACAGCAGTTAAAAACGTAGAAGAACAAATTACTCCCAACCTA
GTTAAAATCAATGCTCTCAACCAAAACTTAGTTGATAGCAAAATGATCGAAATAGACGGTTCCCCCAACAAAAGCAATTT
AGGAGCTAATGCAATTCTAGCCGTCTCCCTAGCAACAGCCAAAGCAGCAGCTAATTCTGTCGGTATGCCATTATATCGCT
ATTTAGGTGGACCACAAGCTAGTCTCCTGCCAGTACCTCTAATGAATGTTATTAACGGTGGTGCTCACGCTGCTAATAAC
GTAGATATTCAAGAATTTATGATTGTACCTGTGGGTGCTACCTCATTTAAAGAGGCATTGCGTTGGGGAGCAGAAGTATT
TGCTACCCTCAGTGGAGTTTTAAAAGACAAAGGTTTACTGGGTGGAGTGGGAGACGAAGGTGGTTATGCTCCCAACTTAG
GGTCAAACCAAGAAGCATTAGATATATTAATTGCAGCTATAGAAAAAGCTGGTTACAAACCAGGAGAACAGGTTGCCTTA
GCATTGGATGTAGCAGCTAGCGAATTTTACAAAGATGGTAACTATATCTATGATGGGGCAACTCATTCTCCTAGTGAATT
AATTGATTATTTAGCTAGTTTGGTCGATCAATATCCTATTGTGTCCATAGAAGATGGTTTACATGAAGAAGATTGGGAAA
GTTGGGTGCAGTTAACTCAAAAGCTAGGTAGCAAAGTTCAATTAGTAGGAGATGATCTATTTGTTACTAATGGTTCTCGT
CTGCAAAAAGGTATTGATATGGCTGCTGGTAACTCAATTTTGATTAAACTCAACCAAATAGGTTCTTTGAGCGAAACTCT
AGAAACTATTGACTTGGCTACTCGTAATAGTTATCGCTCAGTTATTAGTCATCGTTCGGGAGAAACAGAAGATACAACTA
TTGCTGATTTAGCTGTAGGAACTCGCGCAGGTCAGATTAAAACTGGTTCTCTGTGTCGTAGTGAACGAGTGGCTAAATAT
AACCGACTGTTGAGAATTGAAGATGAATTGGGCGATCGCGCTGTCTATGCAGGTGTAATAGGTTTAGGCCCAAAAAGTAG
AAGTTAG

Upstream 100 bases:

>100_bases
CTAAAGATTGCTAGTTATGGCCTAAAGACCAACTTTCCATAACCCTAGATTTAGTATTTAGCCAATGCCATTAAACTTGA
CAAAATAAGGAATAAAAAGT

Downstream 100 bases:

>100_bases
CATAAACCTAGTAAGAACTGACGTATAATACCAAAAATTATAGGGAGAAAAACTCAATTGGCGTCATCCTAGAGTTTCTT
CCTATTTCTGAGGAATTCAA

Product: phosphopyruvate hydratase

Products: NA

Alternate protein names: 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRYSGKGVLTAVKNVEEQITPNL
VKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATAKAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANN
VDIQEFMIVPVGATSFKEALRWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVAL
ALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQKLGSKVQLVGDDLFVTNGSR
LQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRSVISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKY
NRLLRIEDELGDRAVYAGVIGLGPKSRS

Sequences:

>Translated_428_residues
METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRYSGKGVLTAVKNVEEQITPNL
VKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATAKAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANN
VDIQEFMIVPVGATSFKEALRWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVAL
ALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQKLGSKVQLVGDDLFVTNGSR
LQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRSVISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKY
NRLLRIEDELGDRAVYAGVIGLGPKSRS
>Mature_428_residues
METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRYSGKGVLTAVKNVEEQITPNL
VKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATAKAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANN
VDIQEFMIVPVGATSFKEALRWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVAL
ALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQKLGSKVQLVGDDLFVTNGSR
LQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRSVISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKY
NRLLRIEDELGDRAVYAGVIGLGPKSRS

Specific function: Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis

COG id: COG0148

COG function: function code G; Enolase

Gene ontology:

Cell location: Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the bacterial ce

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enolase family

Homologues:

Organism=Homo sapiens, GI301897477, Length=438, Percent_Identity=52.5114155251142, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI301897469, Length=438, Percent_Identity=52.5114155251142, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI5803011, Length=429, Percent_Identity=53.1468531468531, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4503571, Length=429, Percent_Identity=51.981351981352, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI301897479, Length=436, Percent_Identity=48.1651376146789, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI169201331, Length=347, Percent_Identity=25.9365994236311, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI169201757, Length=347, Percent_Identity=25.9365994236311, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI239744207, Length=347, Percent_Identity=25.9365994236311, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310129182, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI310110045, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI310120572, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789141, Length=423, Percent_Identity=60.0472813238771, Blast_Score=477, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI71995829, Length=429, Percent_Identity=51.981351981352, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17536383, Length=429, Percent_Identity=51.981351981352, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI32563855, Length=190, Percent_Identity=50, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6323985, Length=432, Percent_Identity=48.1481481481481, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324974, Length=432, Percent_Identity=48.1481481481481, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324969, Length=432, Percent_Identity=48.1481481481481, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321693, Length=432, Percent_Identity=48.8425925925926, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321968, Length=432, Percent_Identity=48.1481481481481, Blast_Score=355, Evalue=9e-99,
Organism=Drosophila melanogaster, GI24580918, Length=434, Percent_Identity=49.3087557603687, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24580916, Length=434, Percent_Identity=49.3087557603687, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24580920, Length=434, Percent_Identity=49.3087557603687, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24580914, Length=434, Percent_Identity=49.3087557603687, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI281360527, Length=431, Percent_Identity=49.4199535962877, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17137654, Length=431, Percent_Identity=49.4199535962877, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): ENO_TRIEI (Q110V4)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722443.1
- ProteinModelPortal:   Q110V4
- SMR:   Q110V4
- STRING:   Q110V4
- GeneID:   4245327
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2793
- NMPDR:   fig|203124.1.peg.4707
- eggNOG:   COG0148
- HOGENOM:   HBG726599
- OMA:   GSHADSN
- ProtClustDB:   PRK00077
- BioCyc:   TERY203124:TERY_2793-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_00318
- InterPro:   IPR000941
- InterPro:   IPR020810
- InterPro:   IPR020809
- InterPro:   IPR020811
- PIRSF:   PIRSF001400
- PRINTS:   PR00148
- TIGRFAMs:   TIGR01060

Pfam domain/function: PF00113 Enolase_C; PF03952 Enolase_N

EC number: =4.2.1.11

Molecular weight: Translated: 45438; Mature: 45438

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00164 ENOLASE

Important sites: ACT_SITE 206-206 ACT_SITE 336-336 BINDING 156-156 BINDING 165-165 BINDING 284-284 BINDING 311-311 BINDING 336-336 BINDING 387-387

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRY
CCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
SGKGVLTAVKNVEEQITPNLVKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATA
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHH
KAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANNVDIQEFMIVPVGATSFKEAL
HHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHEEEEECCCHHHHHHH
RWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEE
ALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQ
EEEHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
KLGSKVQLVGDDLFVTNGSRLQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRS
HHCCEEEEECCEEEEECCHHHHHCCHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGVI
HHHCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEHHHCCCEEEEEEEE
GLGPKSRS
ECCCCCCC
>Mature Secondary Structure
METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRY
CCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
SGKGVLTAVKNVEEQITPNLVKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATA
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHH
KAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANNVDIQEFMIVPVGATSFKEAL
HHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHEEEEECCCHHHHHHH
RWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEE
ALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQ
EEEHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
KLGSKVQLVGDDLFVTNGSRLQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRS
HHCCEEEEECCEEEEECCHHHHHCCHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGVI
HHHCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEHHHCCCEEEEEEEE
GLGPKSRS
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA