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The map label for this gene is nagB [H]

Identifier: 113476234

GI number: 113476234

Start: 4065862

End: 4066671

Strand: Reverse

Name: nagB [H]

Synonym: Tery_2627

Alternate gene names: 113476234

Gene position: 4066671-4065862 (Counterclockwise)

Preceding gene: 113476237

Following gene: 113476232

Centisome position: 52.47

GC content: 36.17

Gene sequence:

>810_bases
ATGACTTCTAACTTCAGGAATAATACACCCAAACTATATAGACCAATAAAAACTTTCTCAGTTGACGCTCTATCTGTTAG
AATATATCACCAAGAACTAGAAATGGCTAAAGACGCTGCCTTAAGCGTCCTTGAATATTTGCAAAACTTGATTACTAGAC
ACCGAAAAGCAAATGTTATTCTAGCAACCGGAAATTCACAAATTATGTTTCTTAGAGCCTTAACTACTTTAGGTGGTATA
GACTGGTCTCAAGTAACTTTATTTCATTTAGATGAATATCTAGGAATTTCCGCAGATCATCCTGCCAGTTTTCGTTACTA
TCTCCAGGAAAAAGTAGAAAAATTTATTACTCCTCGTCAATTTCATTATATCCAAGGGGATACAAATGAACCCTTAGAAG
AATGCGATCGCTACACTCAACTATTATCCGCTCAACCCATCGATCTAGTTCTTCTAGGCATAGGAGACAATGGACACTTA
GCCTTTAACGACCCCTCCGTAGCAAATTTTAACGATCCTCAAACAATTAAATTAGTCAAACTTGACTTAACCTCCCGTCA
ACAACAAGTAAATCAAGGCCATTTTCCTCATCTTGATGCAGTTCCCCAATACGCATTTACAGTAACCATTCCAGCAATTT
GTTCCGCAAAAAAAATCTTCTGCCTCGCACCAGAAAAACGAAAAGCAGAAGTCATCAGAAATATTTTGTATAATCCTATA
AGTACAATATATCCTGCTTCTATTTTGCGACAAAAATCTCAGGCAACATTATTTTTAGATACTAATTCCGCTAGCCTCAT
TTCTAAATAA

Upstream 100 bases:

>100_bases
CCTTATAGTTAACCATTACCATGAAGATATTCTCAAACCCTAAACTCAAACTTATCCAAAGCAATAACTTAAAAAAATGG
CCTTTCGGTCCTACTAACTT

Downstream 100 bases:

>100_bases
AGGAAGAAAAAAAACTTTCGATCATGATCAAACCTTTGCTGCACCCACATCATGATCAAATCTTTGTTGCACCCACATCT
TGCCAGGGACAATTTTGCCT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTSNFRNNTPKLYRPIKTFSVDALSVRIYHQELEMAKDAALSVLEYLQNLITRHRKANVILATGNSQIMFLRALTTLGGI
DWSQVTLFHLDEYLGISADHPASFRYYLQEKVEKFITPRQFHYIQGDTNEPLEECDRYTQLLSAQPIDLVLLGIGDNGHL
AFNDPSVANFNDPQTIKLVKLDLTSRQQQVNQGHFPHLDAVPQYAFTVTIPAICSAKKIFCLAPEKRKAEVIRNILYNPI
STIYPASILRQKSQATLFLDTNSASLISK

Sequences:

>Translated_269_residues
MTSNFRNNTPKLYRPIKTFSVDALSVRIYHQELEMAKDAALSVLEYLQNLITRHRKANVILATGNSQIMFLRALTTLGGI
DWSQVTLFHLDEYLGISADHPASFRYYLQEKVEKFITPRQFHYIQGDTNEPLEECDRYTQLLSAQPIDLVLLGIGDNGHL
AFNDPSVANFNDPQTIKLVKLDLTSRQQQVNQGHFPHLDAVPQYAFTVTIPAICSAKKIFCLAPEKRKAEVIRNILYNPI
STIYPASILRQKSQATLFLDTNSASLISK
>Mature_268_residues
TSNFRNNTPKLYRPIKTFSVDALSVRIYHQELEMAKDAALSVLEYLQNLITRHRKANVILATGNSQIMFLRALTTLGGID
WSQVTLFHLDEYLGISADHPASFRYYLQEKVEKFITPRQFHYIQGDTNEPLEECDRYTQLLSAQPIDLVLLGIGDNGHLA
FNDPSVANFNDPQTIKLVKLDLTSRQQQVNQGHFPHLDAVPQYAFTVTIPAICSAKKIFCLAPEKRKAEVIRNILYNPIS
TIYPASILRQKSQATLFLDTNSASLISK

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=242, Percent_Identity=23.5537190082645, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19923881, Length=192, Percent_Identity=26.5625, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786893, Length=210, Percent_Identity=24.7619047619048, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789530, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554876, Length=209, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581960, Length=209, Percent_Identity=22.9665071770335, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920764, Length=209, Percent_Identity=22.9665071770335, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 30498; Mature: 30367

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNFRNNTPKLYRPIKTFSVDALSVRIYHQELEMAKDAALSVLEYLQNLITRHRKANVI
CCCCCCCCCHHHHCCHHHEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LATGNSQIMFLRALTTLGGIDWSQVTLFHLDEYLGISADHPASFRYYLQEKVEKFITPRQ
EEECCCCEEHEEEHHHHCCCCHHHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
FHYIQGDTNEPLEECDRYTQLLSAQPIDLVLLGIGDNGHLAFNDPSVANFNDPQTIKLVK
EEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEE
LDLTSRQQQVNQGHFPHLDAVPQYAFTVTIPAICSAKKIFCLAPEKRKAEVIRNILYNPI
EECHHHHHHHCCCCCCCCCCCCCEEEEEEECHHHCCCEEEEECCCHHHHHHHHHHHHCCH
STIYPASILRQKSQATLFLDTNSASLISK
HHHHHHHHHHCCCCEEEEEECCCHHHCCC
>Mature Secondary Structure 
TSNFRNNTPKLYRPIKTFSVDALSVRIYHQELEMAKDAALSVLEYLQNLITRHRKANVI
CCCCCCCCHHHHCCHHHEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LATGNSQIMFLRALTTLGGIDWSQVTLFHLDEYLGISADHPASFRYYLQEKVEKFITPRQ
EEECCCCEEHEEEHHHHCCCCHHHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
FHYIQGDTNEPLEECDRYTQLLSAQPIDLVLLGIGDNGHLAFNDPSVANFNDPQTIKLVK
EEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEE
LDLTSRQQQVNQGHFPHLDAVPQYAFTVTIPAICSAKKIFCLAPEKRKAEVIRNILYNPI
EECHHHHHHHCCCCCCCCCCCCCEEEEEEECHHHCCCEEEEECCCHHHHHHHHHHHHCCH
STIYPASILRQKSQATLFLDTNSASLISK
HHHHHHHHHHCCCCEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA