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The map label for this gene is barA [H]

Identifier: 113475857

GI number: 113475857

Start: 3453420

End: 3455543

Strand: Reverse

Name: barA [H]

Synonym: Tery_2216

Alternate gene names: 113475857

Gene position: 3455543-3453420 (Counterclockwise)

Preceding gene: 113475860

Following gene: 113475847

Centisome position: 44.59

GC content: 32.02

Gene sequence:

>2124_bases
ATGATTAAGAAATTTCAATCCTCTTTTAATAGGATTCTATTGTCGCGAATTTTACTACTTACGATATCAGGACTAGTATT
GGGTCAGTATATAATTTACAGACAAGCACGTTCTACTTTTCTAAACACTGCTCGTCAAAACCTTAAAGAAAGTGCAGATA
GAAAAGCGGAATATCTTCAACAATGGGCAACATCACTAAAGTCAAGTCTAGTTAGTGCGAGTGAAAGCTATGTACTTGAA
TCTGGTACAGTTGAAGAGCATCAAAGTTATATTAAACGGTTAGACGAAATGTTATCTACTCAGATAAGTTGCGTTCAATT
GAGTAACTTACGGACTGAGGAGATCGTCGCGAATACTTGTGGTACTGAAAGAATAGATTCTTTACCGGAAAATATATGGC
CTCAACAGCAAAAACAACTTTTTAGGGACAAGTATAATATTTATGTGAGTTACAGCATCCTAGAACTGTTAAGCGCAGAT
AGCGAATCAAATGGTCAGAAAGTAAATCAAAAAACACAAGTTAGCTTAGTTTGGAGTGTACCAGTGTATGTTAGTGAAGC
TGGCGAAAGAAAATTGCGATATGCCTTAAGTATTAAGTCAGCTTTACCAATGCCAACAAATAGAGAAAGAGGCTCATTTA
CAGGTTCAACTGTAGTAATTAATGTCCCCGAGTACAGGATATTAGCTAGTCTAGATTCTAGGAAACTAGGGCGTAGGATT
TCTGAATTGTCAGACACACAGACTGCAAAGAAACTAGAAAGTATTATGAAAAAGGCAGAGGAAGGTCAAAAACATTTTGC
CCATATATTTTCTATTGAGGAAACAGATATTCTGAGTAAAAATCAGGGAAGTGATAGAAGTAAAAATACTTTCAGAGAAA
TTATTGATAAACTAAAAGAGATATTGCCTAAATTGTTAAGACTTAAATTATCAGAAGATAATGAATTTTTAGCAGGGTAT
GTTGCTATTCCTAGCCCTATAGATAGAGATAATGATAAAGTGTGGGTTGTTTTAGCAATTACACCTATAGATTTTGCTTT
ATCTGGTCTTAGAGAAGTTCAAAAGGTTCTAATTATTCTAATTTTATTTTTACTTGGTGCTAGTATCATAGCAAGTATTT
TTTTGGCTCGTGATTTAGCTATTCCTTTGAAGAAACTCCGAGATTATGCTATTACTTTAAATGATTTAAATGCTCCCAGT
AAAGTACCTCAAGATCTAAAAATTCCTGAGTTTAATCAACTAGCAGTTTCATTACAGAAGATGGTAGAAAGGCTAAATAG
GTGGGCTGATAAAATAGAAGTAGCTTCTAAAGAAGCTCAGGTTGCTAACCAGTTAAAAAGTGAATTTTTAGCTAATATTT
CCCATGAGTTAAGAACTCCACTTAATGGTATTATTGGTTCACTGCAAATAATTTATGATGGTTTTTGTGATACTAGGGAA
GAAGAAATACAGTTCTTGAAACAAGCTAATGATTCAGCTATTCATTTGCTAAGAATTATTGATGATATCCTGGATATTCG
TAAAATTGATGCAAGAAATTTATATATGACATTTGAGAATATCAATATCATCAAGTTATTAGAAGAAACTGTGGATATAT
TTAGATACGATCTTGAACAAAAATCTTTGGTTTTAAAACTAAATGCTTCTGAAGAAAAAATACTTGTTTATGTTGACAAA
AAAGAGTTACAGAAGGTTTTTGAAAATGTTATTAGTAATGCTATTAAGTTTACAGAAAAAGGAAATATTGATATCTCTAT
TTGTAGAAAATATAATCAATGTATTTTTTCTGAAAATCAGAATAATTTAGTTAATGCTCATACTCATAAAGTTAATCAAG
TTTTAGTTACTATTCAAGATACAGGAATTGGTATTGATCCAGAAGAACAGGATAAATTATTTCAGCCTTTTGTTATGGTA
GATGGTACAAAAACTCGTAAATTTGGTGGAAATGGATTAGGATTAGCTATGGCTCGCGGACTGGTGGAAATGATGAATGG
TAATATTCATCTCTATAGTGAAGGTATAGGGCGAGGAACTACAGTTTATATTACTATACCAATTCAGGAAAGATTATCAT
TGGAGAAAAAACAGGATATTTCAACAGAAATTAAATTGAATTAA

Upstream 100 bases:

>100_bases
AGCGCGAAAAGTCCGACTGCACAAATCACTAATTTTACACAACTACCTATCGTCGTTTTCAGGCTTTACTCTAGAACAAA
ATTTTCGGTAAAAAAATGCT

Downstream 100 bases:

>100_bases
AAGGATGAATTAATAGCAATTAGTTTTTTTGTTTTCCTAATATTACATGGCTTGTCAATAATTTTAATTTGACCAATGTC
CTAAGAATAGTTTGAGTTTT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MIKKFQSSFNRILLSRILLLTISGLVLGQYIIYRQARSTFLNTARQNLKESADRKAEYLQQWATSLKSSLVSASESYVLE
SGTVEEHQSYIKRLDEMLSTQISCVQLSNLRTEEIVANTCGTERIDSLPENIWPQQQKQLFRDKYNIYVSYSILELLSAD
SESNGQKVNQKTQVSLVWSVPVYVSEAGERKLRYALSIKSALPMPTNRERGSFTGSTVVINVPEYRILASLDSRKLGRRI
SELSDTQTAKKLESIMKKAEEGQKHFAHIFSIEETDILSKNQGSDRSKNTFREIIDKLKEILPKLLRLKLSEDNEFLAGY
VAIPSPIDRDNDKVWVVLAITPIDFALSGLREVQKVLIILILFLLGASIIASIFLARDLAIPLKKLRDYAITLNDLNAPS
KVPQDLKIPEFNQLAVSLQKMVERLNRWADKIEVASKEAQVANQLKSEFLANISHELRTPLNGIIGSLQIIYDGFCDTRE
EEIQFLKQANDSAIHLLRIIDDILDIRKIDARNLYMTFENINIIKLLEETVDIFRYDLEQKSLVLKLNASEEKILVYVDK
KELQKVFENVISNAIKFTEKGNIDISICRKYNQCIFSENQNNLVNAHTHKVNQVLVTIQDTGIGIDPEEQDKLFQPFVMV
DGTKTRKFGGNGLGLAMARGLVEMMNGNIHLYSEGIGRGTTVYITIPIQERLSLEKKQDISTEIKLN

Sequences:

>Translated_707_residues
MIKKFQSSFNRILLSRILLLTISGLVLGQYIIYRQARSTFLNTARQNLKESADRKAEYLQQWATSLKSSLVSASESYVLE
SGTVEEHQSYIKRLDEMLSTQISCVQLSNLRTEEIVANTCGTERIDSLPENIWPQQQKQLFRDKYNIYVSYSILELLSAD
SESNGQKVNQKTQVSLVWSVPVYVSEAGERKLRYALSIKSALPMPTNRERGSFTGSTVVINVPEYRILASLDSRKLGRRI
SELSDTQTAKKLESIMKKAEEGQKHFAHIFSIEETDILSKNQGSDRSKNTFREIIDKLKEILPKLLRLKLSEDNEFLAGY
VAIPSPIDRDNDKVWVVLAITPIDFALSGLREVQKVLIILILFLLGASIIASIFLARDLAIPLKKLRDYAITLNDLNAPS
KVPQDLKIPEFNQLAVSLQKMVERLNRWADKIEVASKEAQVANQLKSEFLANISHELRTPLNGIIGSLQIIYDGFCDTRE
EEIQFLKQANDSAIHLLRIIDDILDIRKIDARNLYMTFENINIIKLLEETVDIFRYDLEQKSLVLKLNASEEKILVYVDK
KELQKVFENVISNAIKFTEKGNIDISICRKYNQCIFSENQNNLVNAHTHKVNQVLVTIQDTGIGIDPEEQDKLFQPFVMV
DGTKTRKFGGNGLGLAMARGLVEMMNGNIHLYSEGIGRGTTVYITIPIQERLSLEKKQDISTEIKLN
>Mature_707_residues
MIKKFQSSFNRILLSRILLLTISGLVLGQYIIYRQARSTFLNTARQNLKESADRKAEYLQQWATSLKSSLVSASESYVLE
SGTVEEHQSYIKRLDEMLSTQISCVQLSNLRTEEIVANTCGTERIDSLPENIWPQQQKQLFRDKYNIYVSYSILELLSAD
SESNGQKVNQKTQVSLVWSVPVYVSEAGERKLRYALSIKSALPMPTNRERGSFTGSTVVINVPEYRILASLDSRKLGRRI
SELSDTQTAKKLESIMKKAEEGQKHFAHIFSIEETDILSKNQGSDRSKNTFREIIDKLKEILPKLLRLKLSEDNEFLAGY
VAIPSPIDRDNDKVWVVLAITPIDFALSGLREVQKVLIILILFLLGASIIASIFLARDLAIPLKKLRDYAITLNDLNAPS
KVPQDLKIPEFNQLAVSLQKMVERLNRWADKIEVASKEAQVANQLKSEFLANISHELRTPLNGIIGSLQIIYDGFCDTRE
EEIQFLKQANDSAIHLLRIIDDILDIRKIDARNLYMTFENINIIKLLEETVDIFRYDLEQKSLVLKLNASEEKILVYVDK
KELQKVFENVISNAIKFTEKGNIDISICRKYNQCIFSENQNNLVNAHTHKVNQVLVTIQDTGIGIDPEEQDKLFQPFVMV
DGTKTRKFGGNGLGLAMARGLVEMMNGNIHLYSEGIGRGTTVYITIPIQERLSLEKKQDISTEIKLN

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=365, Percent_Identity=31.5068493150685, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=31.8007662835249, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081816, Length=264, Percent_Identity=32.1969696969697, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI48994928, Length=287, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=32.5757575757576, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788393, Length=325, Percent_Identity=26.1538461538462, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1786783, Length=370, Percent_Identity=23.7837837837838, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=282, Percent_Identity=23.758865248227, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786912, Length=302, Percent_Identity=26.158940397351, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=26.4591439688716, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788279, Length=342, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=24.1803278688525, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=25.4098360655738, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=23.0452674897119, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=77, Percent_Identity=41.5584415584416, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80371; Mature: 80371

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKFQSSFNRILLSRILLLTISGLVLGQYIIYRQARSTFLNTARQNLKESADRKAEYLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWATSLKSSLVSASESYVLESGTVEEHQSYIKRLDEMLSTQISCVQLSNLRTEEIVANTC
HHHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
GTERIDSLPENIWPQQQKQLFRDKYNIYVSYSILELLSADSESNGQKVNQKTQVSLVWSV
CHHHHHHCCHHCCCHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEC
PVYVSEAGERKLRYALSIKSALPMPTNRERGSFTGSTVVINVPEYRILASLDSRKLGRRI
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHH
SELSDTQTAKKLESIMKKAEEGQKHFAHIFSIEETDILSKNQGSDRSKNTFREIIDKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHH
ILPKLLRLKLSEDNEFLAGYVAIPSPIDRDNDKVWVVLAITPIDFALSGLREVQKVLIIL
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
ILFLLGASIIASIFLARDLAIPLKKLRDYAITLNDLNAPSKVPQDLKIPEFNQLAVSLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
MVERLNRWADKIEVASKEAQVANQLKSEFLANISHELRTPLNGIIGSLQIIYDGFCDTRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
EEIQFLKQANDSAIHLLRIIDDILDIRKIDARNLYMTFENINIIKLLEETVDIFRYDLEQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC
KSLVLKLNASEEKILVYVDKKELQKVFENVISNAIKFTEKGNIDISICRKYNQCIFSENQ
CCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
NNLVNAHTHKVNQVLVTIQDTGIGIDPEEQDKLFQPFVMVDGTKTRKFGGNGLGLAMARG
CCCEEHHHHEEEEEEEEEECCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCHHHHHHHH
LVEMMNGNIHLYSEGIGRGTTVYITIPIQERLSLEKKQDISTEIKLN
HHHHHCCCEEEEECCCCCCEEEEEEEECHHHHCCHHHHCCCCEEEEC
>Mature Secondary Structure
MIKKFQSSFNRILLSRILLLTISGLVLGQYIIYRQARSTFLNTARQNLKESADRKAEYLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWATSLKSSLVSASESYVLESGTVEEHQSYIKRLDEMLSTQISCVQLSNLRTEEIVANTC
HHHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
GTERIDSLPENIWPQQQKQLFRDKYNIYVSYSILELLSADSESNGQKVNQKTQVSLVWSV
CHHHHHHCCHHCCCHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEC
PVYVSEAGERKLRYALSIKSALPMPTNRERGSFTGSTVVINVPEYRILASLDSRKLGRRI
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHH
SELSDTQTAKKLESIMKKAEEGQKHFAHIFSIEETDILSKNQGSDRSKNTFREIIDKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHH
ILPKLLRLKLSEDNEFLAGYVAIPSPIDRDNDKVWVVLAITPIDFALSGLREVQKVLIIL
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
ILFLLGASIIASIFLARDLAIPLKKLRDYAITLNDLNAPSKVPQDLKIPEFNQLAVSLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
MVERLNRWADKIEVASKEAQVANQLKSEFLANISHELRTPLNGIIGSLQIIYDGFCDTRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
EEIQFLKQANDSAIHLLRIIDDILDIRKIDARNLYMTFENINIIKLLEETVDIFRYDLEQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC
KSLVLKLNASEEKILVYVDKKELQKVFENVISNAIKFTEKGNIDISICRKYNQCIFSENQ
CCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
NNLVNAHTHKVNQVLVTIQDTGIGIDPEEQDKLFQPFVMVDGTKTRKFGGNGLGLAMARG
CCCEEHHHHEEEEEEEEEECCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCHHHHHHHH
LVEMMNGNIHLYSEGIGRGTTVYITIPIQERLSLEKKQDISTEIKLN
HHHHHCCCEEEEECCCCCCEEEEEEEECHHHHCCHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]