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The map label for this gene is cya1 [H]

Identifier: 113475649

GI number: 113475649

Start: 3097987

End: 3099918

Strand: Reverse

Name: cya1 [H]

Synonym: Tery_1986

Alternate gene names: 113475649

Gene position: 3099918-3097987 (Counterclockwise)

Preceding gene: 113475650

Following gene: 113475648

Centisome position: 40.0

GC content: 31.88

Gene sequence:

>1932_bases
ATGGCTATTAAAATTATGGGACTTATACATTTTTGGCAATGCATCAATAAAAAAATTAACTCTCTAAGGATACCAATACC
AGTAATTACCCTTTCTAGCTTTACTATCCTCGGTTTACTATTTTTCAGATACTTAGGAGTATTCCAACCACTAGAACTAG
CAGTATTTGATTTGATGATGCGTTTGCGGTCAATGGAAGAGCCAGATCCTCGGCTTCTAATAGTAGAGATAACTGAAGAG
GATATTCAGTCTTTACAGCAGTGGCCAATCTCCGATAAAACTTTGGCCAAAATTTTAGTATCTCTACAAAAGCATCAACC
TAAAGTAATAGGTCTAGATATTTATCGAGATATTCCTTATCCGCCTGGTGAGTCAGAATTATTGGAACAATTGAAAAAAC
CGAATATTTTTGCTATTACTTATCTTCACAGAGATCTTGATAAAACAGTATTGCCACCTCCCACAATACCAGAAGAAAGA
ATTGGGTTTAATAATATTAATCTTGATCCGAATGGTGTAATTCGTCGTTATTTATTATTTACTTCTCATAAAAATAAAAC
ATTCACAGCTTTTTCTTTAAAATTAGCTATTACTTACCTGAAAGATTATGGAATATTGCCGGTTGTCACTAAAAATAATG
AATATAAATTAGGTGATGTATTATTTAAAGAATTAAAATCAAATTCAGGGGGATACCAAAGAATTGATGATACAGGATAT
AAAATTTTAATAAATTATCGTAATTCTAAATCTGTTGCTCCCAAAGTTAGCATAACTAATGTTTTAAATAATAATTTTGA
CCCTAAATTAGTCAAAAATAAAATTGTTTTGATTGGGACTACAGCTCCTAGTAGCAATGACTTATTTTGGACTCCTTATA
GTTTTGGTAATTCAAAGTTTTTAAGAATGGCAGGAGTCGAGCTTTATGCACATATTACAAGTCAAATTATTAGTGCAGTT
CTTGATGATAGAAAGCTATTTTCATACTGGAATGAATCAATAGAAATACTATGGATTATAGCTTGGTCAATTGTTGGTGC
TAGTCTGACTAGGTATATCAGGAAACCTATGATTTGGATGTTAATAAATTTTCTGAGTTTTAGTATTTTAGGTGGTATTA
GTTATGGTATTTTTATAAATATGCAGTGGATTCCTGTGGTAGCACCATTAGCAGGAATGGTTATTACAGGTGGGATAGTT
ATAGTTTATAACATGCATGAATCATGGCAACAGAAAAATCTGGTGATGAAATTATTAGGTCAGCAAACTTCTCCAGAGAT
TGCTAATGCTCTTTGGCAACAACGTTCAGAGTTGATTAATTCTGGAATTTTACCGGCAAAAACAGTTACAGCAACTATCT
TATTTACTGACTTAAAAAATTTTAGCACTATCTCAGAAAAAAAAACATCGGAAGTTTTAATGATCTGGTTAAATCAATAT
CTGAGTGCTATGACAGATATTGTGATTAATCATAATGGAATAGTCAATAAATTTACTGGAGATGGAATAATGGCAGTATT
TGGTATACCAGTACCTAGTAATACTGTTGAAGAGATTGCTATGGATGCTCAAAATGCAGTTAACTGTGCTTTAGAAATGG
AAGAATATTTGTTGAAGTTTAATTGTCAGTGGCAAAAACAGGGTGATCCAGAAATAAAAATGCGGGTAGGAATTTATACA
GGAAGCATAATAGTTGGTAGTTTAGGAGGAAAAAATCGCTTAGAGTATGGAGTAATTGGTGATAGTGTTAATATTGCTTC
CCGGTTAGAAAGTTTTGAGAAGGAATATCATCGAAGAATTTGTCGAGTTTTGATTGCTGAGGAAACTTTCAAATATCTAG
ATGGAAAATTTAAAGTAGAATTTTGGGGTAATTTTTGTCTGAAAGGGAAGACAAAACCGATTAGTATATATTTGGTTAGT
GGTAAAAAATAA

Upstream 100 bases:

>100_bases
GAACCGGGGAGCTCTTGTTTAATGTTTGTAGTTCATAGCTATCTTAAAATCTGCTGTAAGTGTCGAGAACAACTATTTAA
AACTGATTCCAAGAGGGTTA

Downstream 100 bases:

>100_bases
TTTTTAAATTTGATAATTTCTTCTTAAATTGTCTGTTGAGTAACAAACTGATATTAATAAGCTAAAAATTAAATAAAAAG
TTTTAAGTGTTTAGGGAAAA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MAIKIMGLIHFWQCINKKINSLRIPIPVITLSSFTILGLLFFRYLGVFQPLELAVFDLMMRLRSMEEPDPRLLIVEITEE
DIQSLQQWPISDKTLAKILVSLQKHQPKVIGLDIYRDIPYPPGESELLEQLKKPNIFAITYLHRDLDKTVLPPPTIPEER
IGFNNINLDPNGVIRRYLLFTSHKNKTFTAFSLKLAITYLKDYGILPVVTKNNEYKLGDVLFKELKSNSGGYQRIDDTGY
KILINYRNSKSVAPKVSITNVLNNNFDPKLVKNKIVLIGTTAPSSNDLFWTPYSFGNSKFLRMAGVELYAHITSQIISAV
LDDRKLFSYWNESIEILWIIAWSIVGASLTRYIRKPMIWMLINFLSFSILGGISYGIFINMQWIPVVAPLAGMVITGGIV
IVYNMHESWQQKNLVMKLLGQQTSPEIANALWQQRSELINSGILPAKTVTATILFTDLKNFSTISEKKTSEVLMIWLNQY
LSAMTDIVINHNGIVNKFTGDGIMAVFGIPVPSNTVEEIAMDAQNAVNCALEMEEYLLKFNCQWQKQGDPEIKMRVGIYT
GSIIVGSLGGKNRLEYGVIGDSVNIASRLESFEKEYHRRICRVLIAEETFKYLDGKFKVEFWGNFCLKGKTKPISIYLVS
GKK

Sequences:

>Translated_643_residues
MAIKIMGLIHFWQCINKKINSLRIPIPVITLSSFTILGLLFFRYLGVFQPLELAVFDLMMRLRSMEEPDPRLLIVEITEE
DIQSLQQWPISDKTLAKILVSLQKHQPKVIGLDIYRDIPYPPGESELLEQLKKPNIFAITYLHRDLDKTVLPPPTIPEER
IGFNNINLDPNGVIRRYLLFTSHKNKTFTAFSLKLAITYLKDYGILPVVTKNNEYKLGDVLFKELKSNSGGYQRIDDTGY
KILINYRNSKSVAPKVSITNVLNNNFDPKLVKNKIVLIGTTAPSSNDLFWTPYSFGNSKFLRMAGVELYAHITSQIISAV
LDDRKLFSYWNESIEILWIIAWSIVGASLTRYIRKPMIWMLINFLSFSILGGISYGIFINMQWIPVVAPLAGMVITGGIV
IVYNMHESWQQKNLVMKLLGQQTSPEIANALWQQRSELINSGILPAKTVTATILFTDLKNFSTISEKKTSEVLMIWLNQY
LSAMTDIVINHNGIVNKFTGDGIMAVFGIPVPSNTVEEIAMDAQNAVNCALEMEEYLLKFNCQWQKQGDPEIKMRVGIYT
GSIIVGSLGGKNRLEYGVIGDSVNIASRLESFEKEYHRRICRVLIAEETFKYLDGKFKVEFWGNFCLKGKTKPISIYLVS
GKK
>Mature_642_residues
AIKIMGLIHFWQCINKKINSLRIPIPVITLSSFTILGLLFFRYLGVFQPLELAVFDLMMRLRSMEEPDPRLLIVEITEED
IQSLQQWPISDKTLAKILVSLQKHQPKVIGLDIYRDIPYPPGESELLEQLKKPNIFAITYLHRDLDKTVLPPPTIPEERI
GFNNINLDPNGVIRRYLLFTSHKNKTFTAFSLKLAITYLKDYGILPVVTKNNEYKLGDVLFKELKSNSGGYQRIDDTGYK
ILINYRNSKSVAPKVSITNVLNNNFDPKLVKNKIVLIGTTAPSSNDLFWTPYSFGNSKFLRMAGVELYAHITSQIISAVL
DDRKLFSYWNESIEILWIIAWSIVGASLTRYIRKPMIWMLINFLSFSILGGISYGIFINMQWIPVVAPLAGMVITGGIVI
VYNMHESWQQKNLVMKLLGQQTSPEIANALWQQRSELINSGILPAKTVTATILFTDLKNFSTISEKKTSEVLMIWLNQYL
SAMTDIVINHNGIVNKFTGDGIMAVFGIPVPSNTVEEIAMDAQNAVNCALEMEEYLLKFNCQWQKQGDPEIKMRVGIYTG
SIIVGSLGGKNRLEYGVIGDSVNIASRLESFEKEYHRRICRVLIAEETFKYLDGKFKVEFWGNFCLKGKTKPISIYLVSG
KK

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI10181096, Length=215, Percent_Identity=24.1860465116279, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI10947061, Length=215, Percent_Identity=23.2558139534884, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI167830411, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI34486092, Length=219, Percent_Identity=22.8310502283105, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206632, Length=231, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71989805, Length=227, Percent_Identity=25.5506607929515, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71989822, Length=235, Percent_Identity=25.1063829787234, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568383, Length=164, Percent_Identity=28.6585365853659, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212659371, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534659, Length=208, Percent_Identity=25.9615384615385, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281366320, Length=214, Percent_Identity=26.6355140186916, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161084260, Length=214, Percent_Identity=26.6355140186916, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585694, Length=214, Percent_Identity=24.7663551401869, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 73100; Mature: 72968

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIMGLIHFWQCINKKINSLRIPIPVITLSSFTILGLLFFRYLGVFQPLELAVFDLMM
CEEEEHHHHHHHHHHHHHHCCEECCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLRSMEEPDPRLLIVEITEEDIQSLQQWPISDKTLAKILVSLQKHQPKVIGLDIYRDIPY
HHHCCCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PPGESELLEQLKKPNIFAITYLHRDLDKTVLPPPTIPEERIGFNNINLDPNGVIRRYLLF
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHE
TSHKNKTFTAFSLKLAITYLKDYGILPVVTKNNEYKLGDVLFKELKSNSGGYQRIDDTGY
ECCCCCEEEEEEEEEEEEEHHCCCCEEEEECCCCEEHHHHHHHHHHCCCCCCEEECCCCC
KILINYRNSKSVAPKVSITNVLNNNFDPKLVKNKIVLIGTTAPSSNDLFWTPYSFGNSKF
EEEEEECCCCCCCCCEEEHHHHCCCCCCCEECCCEEEEEECCCCCCCEEECCCCCCCCCE
LRMAGVELYAHITSQIISAVLDDRKLFSYWNESIEILWIIAWSIVGASLTRYIRKPMIWM
EEHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LINFLSFSILGGISYGIFINMQWIPVVAPLAGMVITGGIVIVYNMHESWQQKNLVMKLLG
HHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHHHEECCEEEEEECHHHHHHHHHHHHHHC
QQTSPEIANALWQQRSELINSGILPAKTVTATILFTDLKNFSTISEKKTSEVLMIWLNQY
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHH
LSAMTDIVINHNGIVNKFTGDGIMAVFGIPVPSNTVEEIAMDAQNAVNCALEMEEYLLKF
HHHHHHHEECCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NCQWQKQGDPEIKMRVGIYTGSIIVGSLGGKNRLEYGVIGDSVNIASRLESFEKEYHRRI
CCEECCCCCCCEEEEEEEEECCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
CRVLIAEETFKYLDGKFKVEFWGNFCLKGKTKPISIYLVSGKK
HHHHHHHHHHHHCCCEEEEEEEECEEECCCCCEEEEEEEECCC
>Mature Secondary Structure 
AIKIMGLIHFWQCINKKINSLRIPIPVITLSSFTILGLLFFRYLGVFQPLELAVFDLMM
EEEEHHHHHHHHHHHHHHCCEECCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLRSMEEPDPRLLIVEITEEDIQSLQQWPISDKTLAKILVSLQKHQPKVIGLDIYRDIPY
HHHCCCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PPGESELLEQLKKPNIFAITYLHRDLDKTVLPPPTIPEERIGFNNINLDPNGVIRRYLLF
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHE
TSHKNKTFTAFSLKLAITYLKDYGILPVVTKNNEYKLGDVLFKELKSNSGGYQRIDDTGY
ECCCCCEEEEEEEEEEEEEHHCCCCEEEEECCCCEEHHHHHHHHHHCCCCCCEEECCCCC
KILINYRNSKSVAPKVSITNVLNNNFDPKLVKNKIVLIGTTAPSSNDLFWTPYSFGNSKF
EEEEEECCCCCCCCCEEEHHHHCCCCCCCEECCCEEEEEECCCCCCCEEECCCCCCCCCE
LRMAGVELYAHITSQIISAVLDDRKLFSYWNESIEILWIIAWSIVGASLTRYIRKPMIWM
EEHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LINFLSFSILGGISYGIFINMQWIPVVAPLAGMVITGGIVIVYNMHESWQQKNLVMKLLG
HHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHHHEECCEEEEEECHHHHHHHHHHHHHHC
QQTSPEIANALWQQRSELINSGILPAKTVTATILFTDLKNFSTISEKKTSEVLMIWLNQY
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHH
LSAMTDIVINHNGIVNKFTGDGIMAVFGIPVPSNTVEEIAMDAQNAVNCALEMEEYLLKF
HHHHHHHEECCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NCQWQKQGDPEIKMRVGIYTGSIIVGSLGGKNRLEYGVIGDSVNIASRLESFEKEYHRRI
CCEECCCCCCCEEEEEEEEECCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
CRVLIAEETFKYLDGKFKVEFWGNFCLKGKTKPISIYLVSGKK
HHHHHHHHHHHHCCCEEEEEEEECEEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]