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The map label for this gene is ctaD [H]

Identifier: 113475449

GI number: 113475449

Start: 2711932

End: 2713704

Strand: Reverse

Name: ctaD [H]

Synonym: Tery_1778

Alternate gene names: 113475449

Gene position: 2713704-2711932 (Counterclockwise)

Preceding gene: 113475450

Following gene: 113475448

Centisome position: 35.02

GC content: 41.91

Gene sequence:

>1773_bases
ATGACACAAACACAAATTCCTTTAGATACTCAATCAAAACCGGAAAAACCACACCCGAAGGCGTGGAAATGGTATCACTA
CTTCGGCTATAACATAGACCATAAAGTAATTGGTATTCAATATCTTGTTACTGCCTTCTTCTTTTATCTGCTTGGTGGTC
TAATGGCAATGGGCCTTAGAGCAGAACTCTATACGCCAGATCCAGACGTTCTGGAACCAGATATCTACAATGCTTTCCTG
ACAAATCATGGCACTATAATGATTTTCTTATGGATTATTCCGGCTGCCATCGGTGGTCTCGGGAACTATCTCGTACCTCT
GATGGTAGGAGCAAGAGATATGGCATTTCCCAACTTGAACGCGATCGCCTTCTGGCTAAACCCTCCTGCTGGAGCATTAT
TAATTGCTAGTTTATCTCTGGGAGGGGCACAAAGTGGTTGGACAGCATATCCACCCCTGAGCGTTATTACCAATAACGGG
GGACAATCTTTATGGATTCTCAGTATTGTGTTAGTGGGAACTTCTTCCATTCTGGGTGCCCTGAATTTTATCGCTACGAT
TCTGAAAATGAAAGTTCCTAGCATGAAATGGGATCAGCTTCCCCTGTTCTGCTGGGCAATTCTTGCTACTTCTGTTTTAG
CTTTATGCTCCACTCCTGTTTTAGCAGCAGGGTTGATCATGTTATTATTTGATATCAACTTTGGCACCGGCTTCTTTAGA
CCAGAGATGGGCGGTGATGTAGTTGTATACCAGCACTTATTTTGGTTCTATTCTCACCCGGCAGTTTATCTGATGATTCT
GCCAATATTCGGCATTCTCTCAGAAGTTATTCCTATTCACGCTCGTAAACCAATATTTGGTTATAAAGCGATCGCCTACT
CGAGTCTTGCTATTTGCTTAGTAGGTTTGTTCGTATGGGTACACCATATGTTCACCAGTGGAACCCCACCTTGGATGCGG
ATGTTCTTTACCATCTCTACTCTAATTGTTGCAGTTCCTACAGGAATCAAAATCTTTAGTTGGATAGCTACTCTCTGGGG
GGGAAAAATTCGCTTCACAAGTGGAATGCTTTTTGCCGTCGGTTTATTAGCAATGTTCGTTATGGGAGGACTAAGTGGGG
TGACTCTGGGAACGGTTCCTTTTGATGTTCACGTTCATGATAGTTACTATGTAGTAGGTCACTTCCATTACGTTCTATTT
GGTGGTTCAGTATTTGGTCTGTATTCAGGTATCTATCACTGGTTCCCCAAAATCACAGGCCGAATGTACAACGAAACCTG
GGGTCGAATTCATTTTGTTCTCACTTTAATTGGTACTAACCTCACTTTCTTACCCATGCATCAATTGGGTTTACAAGGAA
TGCCTCGTCGAATTGCTATGTATGACCCTAAGTTTGAATCTCTGAATCATATCTGTACTTATGGGTCAATTCTCTTAGGT
TTATCTGTACTTCCATTCTTAATTAACATGATTTGGAGTTGGATGTATGGGCCAAAAGCTGGGGATAATCCTTGGGGTGG
TTTATCTTTAGAGTGGACTACTAGCTCACCTCCCATTATTGAAAACTGGGAAGTATTACCAGTAGTTACTGAGGGTCCTT
ATGATTTTGGTTCTAAGAAAACTCTTGCTATTCGAGAGCGGTTCAAGCTGATTTCTACACCAAGTTCAAAGGTTAAGGAA
ACAGGTGTACCTGTTTCTGAAGCTGATTCTTCATCCTTATATAGTGGTTCCGGGTCTATTAATGATTCTCAGGATCCTAC
TAGGAAAAGTTAG

Upstream 100 bases:

>100_bases
AAACTTATCACTAAAAAAAAGTGCCCTGGGATTTGCTAAATAATCATTCAAGTCCCTCATTTAATAATAGCTAATTCATA
ATTCTCAAAAATAATTACGG

Downstream 100 bases:

>100_bases
TTATTTTACTCACAGGACTTACGGGGATAAAGCTAAAAAAAACTGTTTTTTCATAGATTTTTATTGAATTAAACAAGGAT
TTATCCAGGTAAGTCCTCAC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MTQTQIPLDTQSKPEKPHPKAWKWYHYFGYNIDHKVIGIQYLVTAFFFYLLGGLMAMGLRAELYTPDPDVLEPDIYNAFL
TNHGTIMIFLWIIPAAIGGLGNYLVPLMVGARDMAFPNLNAIAFWLNPPAGALLIASLSLGGAQSGWTAYPPLSVITNNG
GQSLWILSIVLVGTSSILGALNFIATILKMKVPSMKWDQLPLFCWAILATSVLALCSTPVLAAGLIMLLFDINFGTGFFR
PEMGGDVVVYQHLFWFYSHPAVYLMILPIFGILSEVIPIHARKPIFGYKAIAYSSLAICLVGLFVWVHHMFTSGTPPWMR
MFFTISTLIVAVPTGIKIFSWIATLWGGKIRFTSGMLFAVGLLAMFVMGGLSGVTLGTVPFDVHVHDSYYVVGHFHYVLF
GGSVFGLYSGIYHWFPKITGRMYNETWGRIHFVLTLIGTNLTFLPMHQLGLQGMPRRIAMYDPKFESLNHICTYGSILLG
LSVLPFLINMIWSWMYGPKAGDNPWGGLSLEWTTSSPPIIENWEVLPVVTEGPYDFGSKKTLAIRERFKLISTPSSKVKE
TGVPVSEADSSSLYSGSGSINDSQDPTRKS

Sequences:

>Translated_590_residues
MTQTQIPLDTQSKPEKPHPKAWKWYHYFGYNIDHKVIGIQYLVTAFFFYLLGGLMAMGLRAELYTPDPDVLEPDIYNAFL
TNHGTIMIFLWIIPAAIGGLGNYLVPLMVGARDMAFPNLNAIAFWLNPPAGALLIASLSLGGAQSGWTAYPPLSVITNNG
GQSLWILSIVLVGTSSILGALNFIATILKMKVPSMKWDQLPLFCWAILATSVLALCSTPVLAAGLIMLLFDINFGTGFFR
PEMGGDVVVYQHLFWFYSHPAVYLMILPIFGILSEVIPIHARKPIFGYKAIAYSSLAICLVGLFVWVHHMFTSGTPPWMR
MFFTISTLIVAVPTGIKIFSWIATLWGGKIRFTSGMLFAVGLLAMFVMGGLSGVTLGTVPFDVHVHDSYYVVGHFHYVLF
GGSVFGLYSGIYHWFPKITGRMYNETWGRIHFVLTLIGTNLTFLPMHQLGLQGMPRRIAMYDPKFESLNHICTYGSILLG
LSVLPFLINMIWSWMYGPKAGDNPWGGLSLEWTTSSPPIIENWEVLPVVTEGPYDFGSKKTLAIRERFKLISTPSSKVKE
TGVPVSEADSSSLYSGSGSINDSQDPTRKS
>Mature_589_residues
TQTQIPLDTQSKPEKPHPKAWKWYHYFGYNIDHKVIGIQYLVTAFFFYLLGGLMAMGLRAELYTPDPDVLEPDIYNAFLT
NHGTIMIFLWIIPAAIGGLGNYLVPLMVGARDMAFPNLNAIAFWLNPPAGALLIASLSLGGAQSGWTAYPPLSVITNNGG
QSLWILSIVLVGTSSILGALNFIATILKMKVPSMKWDQLPLFCWAILATSVLALCSTPVLAAGLIMLLFDINFGTGFFRP
EMGGDVVVYQHLFWFYSHPAVYLMILPIFGILSEVIPIHARKPIFGYKAIAYSSLAICLVGLFVWVHHMFTSGTPPWMRM
FFTISTLIVAVPTGIKIFSWIATLWGGKIRFTSGMLFAVGLLAMFVMGGLSGVTLGTVPFDVHVHDSYYVVGHFHYVLFG
GSVFGLYSGIYHWFPKITGRMYNETWGRIHFVLTLIGTNLTFLPMHQLGLQGMPRRIAMYDPKFESLNHICTYGSILLGL
SVLPFLINMIWSWMYGPKAGDNPWGGLSLEWTTSSPPIIENWEVLPVVTEGPYDFGSKKTLAIRERFKLISTPSSKVKET
GVPVSEADSSSLYSGSGSINDSQDPTRKS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=502, Percent_Identity=44.6215139442231, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1786634, Length=511, Percent_Identity=40.3131115459883, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6226519, Length=463, Percent_Identity=46.8682505399568, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=45.9119496855346, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=42.6829268292683, Blast_Score=170, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 65365; Mature: 65233

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTQIPLDTQSKPEKPHPKAWKWYHYFGYNIDHKVIGIQYLVTAFFFYLLGGLMAMGLR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AELYTPDPDVLEPDIYNAFLTNHGTIMIFLWIIPAAIGGLGNYLVPLMVGARDMAFPNLN
EEEECCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
AIAFWLNPPAGALLIASLSLGGAQSGWTAYPPLSVITNNGGQSLWILSIVLVGTSSILGA
EEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHH
LNFIATILKMKVPSMKWDQLPLFCWAILATSVLALCSTPVLAAGLIMLLFDINFGTGFFR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
PEMGGDVVVYQHLFWFYSHPAVYLMILPIFGILSEVIPIHARKPIFGYKAIAYSSLAICL
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VGLFVWVHHMFTSGTPPWMRMFFTISTLIVAVPTGIKIFSWIATLWGGKIRFTSGMLFAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCHHHHHH
GLLAMFVMGGLSGVTLGTVPFDVHVHDSYYVVGHFHYVLFGGSVFGLYSGIYHWFPKITG
HHHHHHHHCCCCCCEEECCEEEEEECCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHC
RMYNETWGRIHFVLTLIGTNLTFLPMHQLGLQGMPRRIAMYDPKFESLNHICTYGSILLG
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
LSVLPFLINMIWSWMYGPKAGDNPWGGLSLEWTTSSPPIIENWEVLPVVTEGPYDFGSKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCC
TLAIRERFKLISTPSSKVKETGVPVSEADSSSLYSGSGSINDSQDPTRKS
CHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQTQIPLDTQSKPEKPHPKAWKWYHYFGYNIDHKVIGIQYLVTAFFFYLLGGLMAMGLR
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AELYTPDPDVLEPDIYNAFLTNHGTIMIFLWIIPAAIGGLGNYLVPLMVGARDMAFPNLN
EEEECCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
AIAFWLNPPAGALLIASLSLGGAQSGWTAYPPLSVITNNGGQSLWILSIVLVGTSSILGA
EEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHH
LNFIATILKMKVPSMKWDQLPLFCWAILATSVLALCSTPVLAAGLIMLLFDINFGTGFFR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
PEMGGDVVVYQHLFWFYSHPAVYLMILPIFGILSEVIPIHARKPIFGYKAIAYSSLAICL
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VGLFVWVHHMFTSGTPPWMRMFFTISTLIVAVPTGIKIFSWIATLWGGKIRFTSGMLFAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCHHHHHH
GLLAMFVMGGLSGVTLGTVPFDVHVHDSYYVVGHFHYVLFGGSVFGLYSGIYHWFPKITG
HHHHHHHHCCCCCCEEECCEEEEEECCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHC
RMYNETWGRIHFVLTLIGTNLTFLPMHQLGLQGMPRRIAMYDPKFESLNHICTYGSILLG
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
LSVLPFLINMIWSWMYGPKAGDNPWGGLSLEWTTSSPPIIENWEVLPVVTEGPYDFGSKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCC
TLAIRERFKLISTPSSKVKETGVPVSEADSSSLYSGSGSINDSQDPTRKS
CHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]