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The map label for this gene is ppnK [H]

Identifier: 113475442

GI number: 113475442

Start: 2693722

End: 2694651

Strand: Reverse

Name: ppnK [H]

Synonym: Tery_1770

Alternate gene names: 113475442

Gene position: 2694651-2693722 (Counterclockwise)

Preceding gene: 113475443

Following gene: 113475437

Centisome position: 34.77

GC content: 39.57

Gene sequence:

>930_bases
ATGGATCTTAAACGAGTAATTATTGCTCATAAGGCTAGAGATGATATAAGCCGTCGTTATGCAGAACAATCTGCGAGAGA
GTTGGAAAAGAGAGGATGTCGAGTCTTAATGGGCCCAAGTGGGCCACAAGATAATCCTTATCCAGTTTTTCTCGCTTCTA
GCAATAATAAAATTGATTTGGCAGTAGTCTTAGGAGGAGATGGTACAATATTAGCTGCAGCTAGAAGTTTAGCACCGGAT
GGAATTCCTATCTTAGCAGTTAATGTAGGAGGACATTTAGGCTTTTTAACCCATAATTTTGAAGATTTTCAGGATACAGA
AAAAGTATGGGATAGGTTATTTGAAGACCGCTATGCATTACAACTAAGAATGATGTTGCAGTCAGCAGTATTTGATGGCG
ATCGCTATAACCTCAAACCAGTCAGCGATAACTTTTTAGCCTTAAATGAGTTTTGCGTTAAACCTGCTTCTGCTGACAGA
ATGCCTACTTCTATTTTAGAACTAGAAATTGATGGTGAGATAGTAGACCAATATCAAGGGGATGGATTAATTGTTGCAAG
TCCCACAGGCTCCACTTGTTATACTGCCTCTGCTAATGGACCAATTATGCACTCTGGCATGGCTTCCATTTCCATAACAC
CAATTTGCCCTCTAAGTCTTTCGAGCCGCCCTATTGTACTTCCTCCTGGTTGTGTAGTTAGTATTTGGCCTTTACATGAT
CACGATCTAAGTACTAAACTCTGGGCAGATGGAGTTCTATGTACTTCTATATGGCCAGGAAAAAGAGTAAATGTGCGTAT
GGCAAATTGTCAAGCTAAGTTTATTATTCTGCGGGAAAATTATTCATTTTTTCAGACTCTCAGAGAAAAACTACTATGGG
CTGGTGCTAGAATTAAGTATCAAAACTACCATCGGAATAGTGAGAGCTGA

Upstream 100 bases:

>100_bases
AGGCTCAGTAAGTTTTTTCCTGCCTAACAACCCAAATAAAAAAGCTATATAATAAAAATTTATACAGGAATTACCCTAAT
TTATATTTCAAATCTAAACT

Downstream 100 bases:

>100_bases
TCATCAACTCAAAAATTTACAAAATAGGTATTTTATGAAAATATAATATCGCGATCGCTATGCTATCAAAATAACTGAAG
CTACCAAAATAATTCCTCCC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MDLKRVIIAHKARDDISRRYAEQSARELEKRGCRVLMGPSGPQDNPYPVFLASSNNKIDLAVVLGGDGTILAAARSLAPD
GIPILAVNVGGHLGFLTHNFEDFQDTEKVWDRLFEDRYALQLRMMLQSAVFDGDRYNLKPVSDNFLALNEFCVKPASADR
MPTSILELEIDGEIVDQYQGDGLIVASPTGSTCYTASANGPIMHSGMASISITPICPLSLSSRPIVLPPGCVVSIWPLHD
HDLSTKLWADGVLCTSIWPGKRVNVRMANCQAKFIILRENYSFFQTLREKLLWAGARIKYQNYHRNSES

Sequences:

>Translated_309_residues
MDLKRVIIAHKARDDISRRYAEQSARELEKRGCRVLMGPSGPQDNPYPVFLASSNNKIDLAVVLGGDGTILAAARSLAPD
GIPILAVNVGGHLGFLTHNFEDFQDTEKVWDRLFEDRYALQLRMMLQSAVFDGDRYNLKPVSDNFLALNEFCVKPASADR
MPTSILELEIDGEIVDQYQGDGLIVASPTGSTCYTASANGPIMHSGMASISITPICPLSLSSRPIVLPPGCVVSIWPLHD
HDLSTKLWADGVLCTSIWPGKRVNVRMANCQAKFIILRENYSFFQTLREKLLWAGARIKYQNYHRNSES
>Mature_309_residues
MDLKRVIIAHKARDDISRRYAEQSARELEKRGCRVLMGPSGPQDNPYPVFLASSNNKIDLAVVLGGDGTILAAARSLAPD
GIPILAVNVGGHLGFLTHNFEDFQDTEKVWDRLFEDRYALQLRMMLQSAVFDGDRYNLKPVSDNFLALNEFCVKPASADR
MPTSILELEIDGEIVDQYQGDGLIVASPTGSTCYTASANGPIMHSGMASISITPICPLSLSSRPIVLPPGCVVSIWPLHD
HDLSTKLWADGVLCTSIWPGKRVNVRMANCQAKFIILRENYSFFQTLREKLLWAGARIKYQNYHRNSES

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=265, Percent_Identity=31.6981132075472, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788968, Length=244, Percent_Identity=32.7868852459016, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320794, Length=187, Percent_Identity=36.8983957219251, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322509, Length=180, Percent_Identity=35.5555555555556, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325068, Length=180, Percent_Identity=34.4444444444444, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI161077047, Length=201, Percent_Identity=37.3134328358209, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573830, Length=201, Percent_Identity=37.3134328358209, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573828, Length=201, Percent_Identity=37.3134328358209, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573826, Length=201, Percent_Identity=37.3134328358209, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573832, Length=201, Percent_Identity=37.3134328358209, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653422, Length=279, Percent_Identity=30.1075268817204, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363323, Length=279, Percent_Identity=30.1075268817204, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=30.2158273381295, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281363321, Length=279, Percent_Identity=30.1075268817204, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34298; Mature: 34298

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKRVIIAHKARDDISRRYAEQSARELEKRGCRVLMGPSGPQDNPYPVFLASSNNKIDL
CCCHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCEEEE
AVVLGGDGTILAAARSLAPDGIPILAVNVGGHLGFLTHNFEDFQDTEKVWDRLFEDRYAL
EEEECCCCEEEEEHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QLRMMLQSAVFDGDRYNLKPVSDNFLALNEFCVKPASADRMPTSILELEIDGEIVDQYQG
HHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCCCCCEEEEEEECCCEECCCCC
DGLIVASPTGSTCYTASANGPIMHSGMASISITPICPLSLSSRPIVLPPGCVVSIWPLHD
CEEEEECCCCCEEEEECCCCCEEECCCCEEEECEECCCCCCCCCEEECCCCEEEEEECCC
HDLSTKLWADGVLCTSIWPGKRVNVRMANCQAKFIILRENYSFFQTLREKLLWAGARIKY
CCCCCCHHCCCEEEECCCCCCEEEEEEECCEEEEEEEECCCHHHHHHHHHHHHCCCEEEE
QNYHRNSES
ECCCCCCCC
>Mature Secondary Structure
MDLKRVIIAHKARDDISRRYAEQSARELEKRGCRVLMGPSGPQDNPYPVFLASSNNKIDL
CCCHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCEEEE
AVVLGGDGTILAAARSLAPDGIPILAVNVGGHLGFLTHNFEDFQDTEKVWDRLFEDRYAL
EEEECCCCEEEEEHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QLRMMLQSAVFDGDRYNLKPVSDNFLALNEFCVKPASADRMPTSILELEIDGEIVDQYQG
HHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCCCCCEEEEEEECCCEECCCCC
DGLIVASPTGSTCYTASANGPIMHSGMASISITPICPLSLSSRPIVLPPGCVVSIWPLHD
CEEEEECCCCCEEEEECCCCCEEECCCCEEEECEECCCCCCCCCEEECCCCEEEEEECCC
HDLSTKLWADGVLCTSIWPGKRVNVRMANCQAKFIILRENYSFFQTLREKLLWAGARIKY
CCCCCCHHCCCEEEECCCCCCEEEEEEECCEEEEEEEECCCHHHHHHHHHHHHCCCEEEE
QNYHRNSES
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA