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The map label for this gene is asd [H]

Identifier: 113474443

GI number: 113474443

Start: 943156

End: 944193

Strand: Direct

Name: asd [H]

Synonym: Tery_0587

Alternate gene names: 113474443

Gene position: 943156-944193 (Clockwise)

Preceding gene: 113474439

Following gene: 113474444

Centisome position: 12.17

GC content: 38.92

Gene sequence:

>1038_bases
TTGTCAGATTCATACAGAGTAGCAATATTAGGAGCAACTGGTGCAGTAGGTACGGAATTACTAGAATTACTGGAAACTCG
GAACTTTCCAGTAGGAGAATTAAAACTCTTAGCTTCAGAATTTTCAGCGGGTAAGACCTTAAAATTTAAGGAACAAAGTT
TACAAGTAGAAGCTGTAACAAATGATTCATTTAATAAAGTAGATTTAGTGCTAGCATCAGCAGGTGCATCTGTATCAAAA
GTATGGGCAAAGAAAGCAGTAGAGGCTGGAGCTGTAGTTATTGACAATTCTAGTGCTTTTCGTATGGACTCCCAAGTACC
TCTTGTAGTCCCAGAAGTTAACCCAGAAGCAGCGGCTTTACATAAAGGTATAGTTGCTAACCCTAACTGCACAACAATAT
TAATGAGTGTAGCAGTGTGGCCATTGCACAAAATCCAGCCAGTCCAAAGGTTAGTAGTGGCCACTTATCAATCAGCAAGT
GGGGCCGGGTCAAGGGCTATGGCAGAAATGAAAATTCAGGCCCAAGAAATCTTAGATGGAAAAACTCCAACAACAGATAT
TTTTCCCTACCCATTAGCATTTAATTTGTTCCCTCATAATTCTCAACTCAATGAGCAGGGATATTGTCAAGAAGAAATGA
AAATGCTTGATGAAACCAGAAAAATATTTGGCTCTAAGGAACTGAGAATTACAGCAACTTGTATTCGAGTACCAGTATTA
AGAGCTCATTCAGAAGCAATTAATTTGGAATTTGCTGAACCATTTAGTGTAGTTAAAGCACGGGAAGTATTAAGTCAAGC
ACCAGGAGTGACACTGGTAGAAAATTGGCAAGAAAATTATTTTCCTATGCCTATGGTTGCAAGTGGTAAAGATGATGTAT
TGGTGGGGAGAATTCGTCAGGATATTTCTCAAGCTGAGGGGTTAGAATTATGGTTAAGTGGAGACCAGGTAAGAAAAGGA
GCTGCCTTGAATGCAGTACAAATAGCTGAATTATTGGTGGCAAAAAATTGGCTGAGAATACCAGTAGGAACATTTTAA

Upstream 100 bases:

>100_bases
ATATAATTTTAAAATCTTATATAAAAAATTATTATATTTAGTTAAAAACTCTAGATTAAAATAAAACTGTTTAAAATTTA
AACTAAAGGAGGAAAATAAT

Downstream 100 bases:

>100_bases
TTCAGTATGCTAAAAAAAACAAAAAGGGGTCATAATTGAGTGCCAATTTCTGATTTTTTATATAGATGGAATAGGTATAC
TGAAGAAAGTGATAACTTGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSDSYRVAILGATGAVGTELLELLETRNFPVGELKLLASEFSAGKTLKFKEQSLQVEAVTNDSFNKVDLVLASAGASVSK
VWAKKAVEAGAVVIDNSSAFRMDSQVPLVVPEVNPEAAALHKGIVANPNCTTILMSVAVWPLHKIQPVQRLVVATYQSAS
GAGSRAMAEMKIQAQEILDGKTPTTDIFPYPLAFNLFPHNSQLNEQGYCQEEMKMLDETRKIFGSKELRITATCIRVPVL
RAHSEAINLEFAEPFSVVKAREVLSQAPGVTLVENWQENYFPMPMVASGKDDVLVGRIRQDISQAEGLELWLSGDQVRKG
AALNAVQIAELLVAKNWLRIPVGTF

Sequences:

>Translated_345_residues
MSDSYRVAILGATGAVGTELLELLETRNFPVGELKLLASEFSAGKTLKFKEQSLQVEAVTNDSFNKVDLVLASAGASVSK
VWAKKAVEAGAVVIDNSSAFRMDSQVPLVVPEVNPEAAALHKGIVANPNCTTILMSVAVWPLHKIQPVQRLVVATYQSAS
GAGSRAMAEMKIQAQEILDGKTPTTDIFPYPLAFNLFPHNSQLNEQGYCQEEMKMLDETRKIFGSKELRITATCIRVPVL
RAHSEAINLEFAEPFSVVKAREVLSQAPGVTLVENWQENYFPMPMVASGKDDVLVGRIRQDISQAEGLELWLSGDQVRKG
AALNAVQIAELLVAKNWLRIPVGTF
>Mature_344_residues
SDSYRVAILGATGAVGTELLELLETRNFPVGELKLLASEFSAGKTLKFKEQSLQVEAVTNDSFNKVDLVLASAGASVSKV
WAKKAVEAGAVVIDNSSAFRMDSQVPLVVPEVNPEAAALHKGIVANPNCTTILMSVAVWPLHKIQPVQRLVVATYQSASG
AGSRAMAEMKIQAQEILDGKTPTTDIFPYPLAFNLFPHNSQLNEQGYCQEEMKMLDETRKIFGSKELRITATCIRVPVLR
AHSEAINLEFAEPFSVVKAREVLSQAPGVTLVENWQENYFPMPMVASGKDDVLVGRIRQDISQAEGLELWLSGDQVRKGA
ALNAVQIAELLVAKNWLRIPVGTF

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=35.9050445103858, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=28.5318559556787, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=397, Percent_Identity=28.463476070529, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37579; Mature: 37447

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSYRVAILGATGAVGTELLELLETRNFPVGELKLLASEFSAGKTLKFKEQSLQVEAVT
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEHHCEEEEEEC
NDSFNKVDLVLASAGASVSKVWAKKAVEAGAVVIDNSSAFRMDSQVPLVVPEVNPEAAAL
CCCCCEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEECCCCCEEEECCCCHHHHH
HKGIVANPNCTTILMSVAVWPLHKIQPVQRLVVATYQSASGAGSRAMAEMKIQAQEILDG
HCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KTPTTDIFPYPLAFNLFPHNSQLNEQGYCQEEMKMLDETRKIFGSKELRITATCIRVPVL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHH
RAHSEAINLEFAEPFSVVKAREVLSQAPGVTLVENWQENYFPMPMVASGKDDVLVGRIRQ
HCCCHHEEEEECCHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCEEECCCCCEEHHHHHH
DISQAEGLELWLSGDQVRKGAALNAVQIAELLVAKNWLRIPVGTF
HHHHCCCEEEEECCCHHHCCCCCHHHHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure 
SDSYRVAILGATGAVGTELLELLETRNFPVGELKLLASEFSAGKTLKFKEQSLQVEAVT
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEHHCEEEEEEC
NDSFNKVDLVLASAGASVSKVWAKKAVEAGAVVIDNSSAFRMDSQVPLVVPEVNPEAAAL
CCCCCEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEECCCCCEEEECCCCHHHHH
HKGIVANPNCTTILMSVAVWPLHKIQPVQRLVVATYQSASGAGSRAMAEMKIQAQEILDG
HCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KTPTTDIFPYPLAFNLFPHNSQLNEQGYCQEEMKMLDETRKIFGSKELRITATCIRVPVL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHH
RAHSEAINLEFAEPFSVVKAREVLSQAPGVTLVENWQENYFPMPMVASGKDDVLVGRIRQ
HCCCHHEEEEECCHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCEEECCCCCEEHHHHHH
DISQAEGLELWLSGDQVRKGAALNAVQIAELLVAKNWLRIPVGTF
HHHHCCCEEEEECCCHHHCCCCCHHHHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]