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The map label for this gene is eno [C]

Identifier: 110835417

GI number: 110835417

Start: 2896177

End: 2897043

Strand: Reverse

Name: eno [C]

Synonym: ABO_2556

Alternate gene names: 110835417

Gene position: 2897043-2896177 (Counterclockwise)

Preceding gene: 110835418

Following gene: 110835416

Centisome position: 92.85

GC content: 53.06

Gene sequence:

>867_bases
ATGGATTATCAAGACATCAAGACCGAGCTGTCCGAAAATATTTTGACTATTACCCTTAACCGTCCTGATCGCCTTAATGC
TTTTACTTTGCGCATGAAAGACGAAATGGTTGATGCCCTGGCTGAAGCAGACAGCAATGATGATATCCGGGCCGTTATCG
TTACGGGGGCGGGTAAGGTTTTCTGTGCAGGAATGGAAATGGAGCCGGAAGGTGGCGGCCACCTGTTTGGCTATGACGAC
GCTGAGGGTATGGAGCCGCCGTTAGAGACCATCCGCGATTCCGGCGGCGAACTGTCGCTGGCAATCTATAATTGTCGCAA
GCCCGTGATCGCCGCCATTAACGGCGCGGCGGTGGGGGTGGGGATCACTATGACCCTACCCATGGATATTCGCCTGGTGG
CGACCAACAGCAAAATCGGTTTTGTTTTTACCCAGCGCGGTGTAACGCCGGAGGCCTGTTCTTCTTGGTTCCTGCCGCGG
GTGGTGGGTATACAGAAAGCGCTGGAGTGGGTGATTAGCGGTGATATTTTCATGGCTGAAGAAGGTGAGAAGGCAGGGCT
GTTCCACAGTGTGCATGACAAAGACGAGGTGGTGGAGGTGGCCCGCTGCATCGCTCGAAAGCTGATTGCAAAAAGTTCGC
CGGTGGCGGTGGCGTTGGCCAAGCAGATGTTGTGGCGCAACCCGAACTTTTCCCACCCAGCCGAAGCCCATGTGGTGGAA
TCAAAAATGATTTATTGGTCCAATGAATTTTGGGACGGGAAAGACGGGTTTACCGCTTTTCTTGAAAAGCGCCCGCCGCG
TTTTGATACTTCGCTGGCGGATGTGCCCAAACAATTTGATTTTTGGGAAGCGCCTCCGATTAAATAA

Upstream 100 bases:

>100_bases
ATGTTCGATGCCTTGCCATCGGGGTATGCTCAGGGTCAAACCGTGCTACTGAGCCTCTATCGATAACGACTGAAAACCGC
ACAACCCCAGTGGAGTGATC

Downstream 100 bases:

>100_bases
GGTGGTTTTTTGGGCCGCCGCTTGGCGGCCTTTTTGCGTGTGCGTCGTTTTGCGGCGAAAATTATGAGGCAGAGAGTGAT
GAAAAAAGAAACCATTGCCA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDYQDIKTELSENILTITLNRPDRLNAFTLRMKDEMVDALAEADSNDDIRAVIVTGAGKVFCAGMEMEPEGGGHLFGYDD
AEGMEPPLETIRDSGGELSLAIYNCRKPVIAAINGAAVGVGITMTLPMDIRLVATNSKIGFVFTQRGVTPEACSSWFLPR
VVGIQKALEWVISGDIFMAEEGEKAGLFHSVHDKDEVVEVARCIARKLIAKSSPVAVALAKQMLWRNPNFSHPAEAHVVE
SKMIYWSNEFWDGKDGFTAFLEKRPPRFDTSLADVPKQFDFWEAPPIK

Sequences:

>Translated_288_residues
MDYQDIKTELSENILTITLNRPDRLNAFTLRMKDEMVDALAEADSNDDIRAVIVTGAGKVFCAGMEMEPEGGGHLFGYDD
AEGMEPPLETIRDSGGELSLAIYNCRKPVIAAINGAAVGVGITMTLPMDIRLVATNSKIGFVFTQRGVTPEACSSWFLPR
VVGIQKALEWVISGDIFMAEEGEKAGLFHSVHDKDEVVEVARCIARKLIAKSSPVAVALAKQMLWRNPNFSHPAEAHVVE
SKMIYWSNEFWDGKDGFTAFLEKRPPRFDTSLADVPKQFDFWEAPPIK
>Mature_288_residues
MDYQDIKTELSENILTITLNRPDRLNAFTLRMKDEMVDALAEADSNDDIRAVIVTGAGKVFCAGMEMEPEGGGHLFGYDD
AEGMEPPLETIRDSGGELSLAIYNCRKPVIAAINGAAVGVGITMTLPMDIRLVATNSKIGFVFTQRGVTPEACSSWFLPR
VVGIQKALEWVISGDIFMAEEGEKAGLFHSVHDKDEVVEVARCIARKLIAKSSPVAVALAKQMLWRNPNFSHPAEAHVVE
SKMIYWSNEFWDGKDGFTAFLEKRPPRFDTSLADVPKQFDFWEAPPIK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=257, Percent_Identity=30.7392996108949, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI70995211, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI31542718, Length=260, Percent_Identity=28.8461538461538, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4757968, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI49355787, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI68989263, Length=199, Percent_Identity=28.1407035175879, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4757966, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI51538581, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI25453481, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI51538573, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4502327, Length=268, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI116235487, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=270, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=29.8449612403101, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788597, Length=268, Percent_Identity=28.3582089552239, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082183, Length=282, Percent_Identity=24.468085106383, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790281, Length=102, Percent_Identity=35.2941176470588, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=261, Percent_Identity=28.3524904214559, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=229, Percent_Identity=34.9344978165939, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=266, Percent_Identity=29.3233082706767, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=217, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=274, Percent_Identity=27.3722627737226, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=27.0642201834862, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=181, Percent_Identity=27.0718232044199, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=249, Percent_Identity=24.8995983935743, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129971, Length=271, Percent_Identity=30.6273062730627, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24653477, Length=271, Percent_Identity=30.6273062730627, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24653139, Length=263, Percent_Identity=29.6577946768061, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19920382, Length=219, Percent_Identity=30.1369863013699, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654903, Length=203, Percent_Identity=26.1083743842365, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=23.6714975845411, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583165, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650670, Length=188, Percent_Identity=23.936170212766, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31856; Mature: 31856

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQDIKTELSENILTITLNRPDRLNAFTLRMKDEMVDALAEADSNDDIRAVIVTGAGKV
CCHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEEEECCCEE
FCAGMEMEPEGGGHLFGYDDAEGMEPPLETIRDSGGELSLAIYNCRKPVIAAINGAAVGV
EEECCEECCCCCCEEECCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEE
GITMTLPMDIRLVATNSKIGFVFTQRGVTPEACSSWFLPRVVGIQKALEWVISGDIFMAE
EEEEEECCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
EGEKAGLFHSVHDKDEVVEVARCIARKLIAKSSPVAVALAKQMLWRNPNFSHPAEAHVVE
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHEEEE
SKMIYWSNEFWDGKDGFTAFLEKRPPRFDTSLADVPKQFDFWEAPPIK
EEEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDYQDIKTELSENILTITLNRPDRLNAFTLRMKDEMVDALAEADSNDDIRAVIVTGAGKV
CCHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEEEECCCEE
FCAGMEMEPEGGGHLFGYDDAEGMEPPLETIRDSGGELSLAIYNCRKPVIAAINGAAVGV
EEECCEECCCCCCEEECCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEE
GITMTLPMDIRLVATNSKIGFVFTQRGVTPEACSSWFLPRVVGIQKALEWVISGDIFMAE
EEEEEECCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
EGEKAGLFHSVHDKDEVVEVARCIARKLIAKSSPVAVALAKQMLWRNPNFSHPAEAHVVE
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHEEEE
SKMIYWSNEFWDGKDGFTAFLEKRPPRFDTSLADVPKQFDFWEAPPIK
EEEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA