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The map label for this gene is cobO [H]

Identifier: 110835227

GI number: 110835227

Start: 2690389

End: 2691000

Strand: Reverse

Name: cobO [H]

Synonym: ABO_2366

Alternate gene names: 110835227

Gene position: 2691000-2690389 (Counterclockwise)

Preceding gene: 110835228

Following gene: 110835226

Centisome position: 86.25

GC content: 55.56

Gene sequence:

>612_bases
ATGCGTGATGATGCGAAAACCCCAGAGCGCCATGCTTACCGCATGGCAAAGAAACAGGAAATCATGCAGCAACGGATTGC
TCGCGCGGATAAGGATCAGGGCATTCTTCTGGTGCTCACCGGGCCGGGCAAAGGAAAAAGCAGTTCCGGTTTTGGCATGC
TGGCCAGAGCATTGGGCCATGGCATGAAAGTGGGCGTGGTGCAGTTTATTAAAGGGGCGTTCAGTACCGGAGAAGACGCC
TTTTTCCGTGATCAGCCGAACGTGGATTACCACGTGATGGGGGAAGGCTATACCTGGGATACCCAGGACCGCGAGCGGGA
CGTGGCGGCAGCCGGTGCTGCGTGGGAGATTGCCCGTGCCATGCTGCGCGACGACAGCTATCACATGGTGTTGCTCGATG
AGCTCAATATTGCTCTTCGTTACGAATACCTGGATTTAGACCGGGTGCTGGACGACCTGCAAAACCGCCCGGCCATGCAG
CACGCCATTGTCACCGGTCGCTATGCTCCCAAACAATTAATCGAACTCGCCGATACCGTTACGGAAATGAAAGTGGTGAA
GCATGCGTTTAAGGATTTAGGAGTTCGAGCGCAGAAGGGCGTCGAGCTGTGA

Upstream 100 bases:

>100_bases
CCTTCGGCTCCGCAGATTGTGGCGGATATTTTTAGCGGACAATTCCGCACCGACACACTTTCCCCTGATCACAATGCCCC
TTCTCGAACAGGACACGACC

Downstream 100 bases:

>100_bases
AGGGCCTTTTGACGTTCAAATGTTCGGAAAAAATACGGGGCGAGTGGGCCGGCAAGGTCACTGTAGGTGCTGGGTTGCGC
TTCAAGTTTGAGATTGTAAC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRDDAKTPERHAYRMAKKQEIMQQRIARADKDQGILLVLTGPGKGKSSSGFGMLARALGHGMKVGVVQFIKGAFSTGEDA
FFRDQPNVDYHVMGEGYTWDTQDRERDVAAAGAAWEIARAMLRDDSYHMVLLDELNIALRYEYLDLDRVLDDLQNRPAMQ
HAIVTGRYAPKQLIELADTVTEMKVVKHAFKDLGVRAQKGVEL

Sequences:

>Translated_203_residues
MRDDAKTPERHAYRMAKKQEIMQQRIARADKDQGILLVLTGPGKGKSSSGFGMLARALGHGMKVGVVQFIKGAFSTGEDA
FFRDQPNVDYHVMGEGYTWDTQDRERDVAAAGAAWEIARAMLRDDSYHMVLLDELNIALRYEYLDLDRVLDDLQNRPAMQ
HAIVTGRYAPKQLIELADTVTEMKVVKHAFKDLGVRAQKGVEL
>Mature_203_residues
MRDDAKTPERHAYRMAKKQEIMQQRIARADKDQGILLVLTGPGKGKSSSGFGMLARALGHGMKVGVVQFIKGAFSTGEDA
FFRDQPNVDYHVMGEGYTWDTQDRERDVAAAGAAWEIARAMLRDDSYHMVLLDELNIALRYEYLDLDRVLDDLQNRPAMQ
HAIVTGRYAPKQLIELADTVTEMKVVKHAFKDLGVRAQKGVEL

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=47.9381443298969, Blast_Score=184, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22838; Mature: 22838

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDDAKTPERHAYRMAKKQEIMQQRIARADKDQGILLVLTGPGKGKSSSGFGMLARALGH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
GMKVGVVQFIKGAFSTGEDAFFRDQPNVDYHVMGEGYTWDTQDRERDVAAAGAAWEIARA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHH
MLRDDSYHMVLLDELNIALRYEYLDLDRVLDDLQNRPAMQHAIVTGRYAPKQLIELADTV
HHCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
TEMKVVKHAFKDLGVRAQKGVEL
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRDDAKTPERHAYRMAKKQEIMQQRIARADKDQGILLVLTGPGKGKSSSGFGMLARALGH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
GMKVGVVQFIKGAFSTGEDAFFRDQPNVDYHVMGEGYTWDTQDRERDVAAAGAAWEIARA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHH
MLRDDSYHMVLLDELNIALRYEYLDLDRVLDDLQNRPAMQHAIVTGRYAPKQLIELADTV
HHCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
TEMKVVKHAFKDLGVRAQKGVEL
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]