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The map label for this gene is slyD [H]

Identifier: 110835224

GI number: 110835224

Start: 2687303

End: 2687791

Strand: Direct

Name: slyD [H]

Synonym: ABO_2363

Alternate gene names: 110835224

Gene position: 2687303-2687791 (Clockwise)

Preceding gene: 110835221

Following gene: 110835225

Centisome position: 86.13

GC content: 56.85

Gene sequence:

>489_bases
ATGCAAATTTCTGAAAATGCCGTAGTGTCCATCCACTACACCCTGACCAACAACGCCGGTGAAACCATCGATTCTTCCAT
TGAGCGTGGCGAGCCCTTGGCGTACCTGCACGGCGCCGGCAACATCATTCCGGGCCTGGAAAATGCCCTGCTAGGCAAAG
TCTCTGGCGACAAGCTGGATGTCACGGTTACTCCGGAAGAAGGCTACGGCGAGCGTCACGAGCAGCTGATTCAGCAGGTG
CCGAAGACTGCCTTTGAAGGCAACGAAGACAACCTGCAGCCAGGTATGCAGTTCCAGGCGCAAACCGAAGCGGGCGATCG
CGTTTTCACCATCACCGCCATTGATGGCGATGAAGTGACCGTCGATGGTAACCACCCACTGGCAGGTGAAACGCTGAACT
TCGCCGTGGAAGTGACTGACGTACGCGAAGCGTCCGACGAAGAAAAAGAGCACGGCCACGTACACGGCCCGGAAGGTCAC
GATCACTGA

Upstream 100 bases:

>100_bases
AGAATGTCCGCCGACCTGAATACAGAACGCGGTCAGGCCACTCAAGCGTCATGACCGACACGTTCCTTATTCCGAATTCA
TCTACCCCTAAAGGGTTTCC

Downstream 100 bases:

>100_bases
TCGCTGACGGCTCGCAGAAAAGAGGCTCCTACGGGAGCCTTTTTTTACCGCTCTACGGCGGCAACAGGTTGGCACTGCAG
GCCTCCTACATCGTCCCGTC

Product: fkbp-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MQISENAVVSIHYTLTNNAGETIDSSIERGEPLAYLHGAGNIIPGLENALLGKVSGDKLDVTVTPEEGYGERHEQLIQQV
PKTAFEGNEDNLQPGMQFQAQTEAGDRVFTITAIDGDEVTVDGNHPLAGETLNFAVEVTDVREASDEEKEHGHVHGPEGH
DH

Sequences:

>Translated_162_residues
MQISENAVVSIHYTLTNNAGETIDSSIERGEPLAYLHGAGNIIPGLENALLGKVSGDKLDVTVTPEEGYGERHEQLIQQV
PKTAFEGNEDNLQPGMQFQAQTEAGDRVFTITAIDGDEVTVDGNHPLAGETLNFAVEVTDVREASDEEKEHGHVHGPEGH
DH
>Mature_162_residues
MQISENAVVSIHYTLTNNAGETIDSSIERGEPLAYLHGAGNIIPGLENALLGKVSGDKLDVTVTPEEGYGERHEQLIQQV
PKTAFEGNEDNLQPGMQFQAQTEAGDRVFTITAIDGDEVTVDGNHPLAGETLNFAVEVTDVREASDEEKEHGHVHGPEGH
DH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=47.2972972972973, Blast_Score=124, Evalue=2e-30,
Organism=Escherichia coli, GI1786211, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17478; Mature: 17478

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISENAVVSIHYTLTNNAGETIDSSIERGEPLAYLHGAGNIIPGLENALLGKVSGDKLD
CCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHEEECCCCCEEE
VTVTPEEGYGERHEQLIQQVPKTAFEGNEDNLQPGMQFQAQTEAGDRVFTITAIDGDEVT
EEECCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEE
VDGNHPLAGETLNFAVEVTDVREASDEEKEHGHVHGPEGHDH
ECCCCCCCCCEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQISENAVVSIHYTLTNNAGETIDSSIERGEPLAYLHGAGNIIPGLENALLGKVSGDKLD
CCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCCCHHEEECCCCCEEE
VTVTPEEGYGERHEQLIQQVPKTAFEGNEDNLQPGMQFQAQTEAGDRVFTITAIDGDEVT
EEECCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEE
VDGNHPLAGETLNFAVEVTDVREASDEEKEHGHVHGPEGHDH
ECCCCCCCCCEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]