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The map label for this gene is hslV

Identifier: 110835105

GI number: 110835105

Start: 2564724

End: 2565266

Strand: Direct

Name: hslV

Synonym: ABO_2244

Alternate gene names: 110835105

Gene position: 2564724-2565266 (Clockwise)

Preceding gene: 110835104

Following gene: 110835106

Centisome position: 82.2

GC content: 58.75

Gene sequence:

>543_bases
GTGGAGCAGTATCGCGGTACAACCATTGTTTCTGTTCGTCGAGGCAACAACGTCGTCATCGGTGGCGATGGCCAGGTTAG
CCTGGGCAACACTGTCATGAAGGGCAACGCCCGCAAGGTTCGTCGGCTTTTTCATGGCAAAGTCATTGCCGGATTCGCCG
GTGGCACCGCCGACGCCTTTACCCTGTTCGAACGTTTCGAAGCCCAGCTGGAAAAGCACCAGGGCCACTTAGTCCGCGCC
GCCGTGGAGCTGGCCAAAGACTGGCGTACCGACCGAGCCCTACGCCGGCTGGAAGCCCTGCTGGCAGTCGCCGACAAGGA
AAGTTCACTAATTATTACCGGCAACGGCGACGTGATTGAGCCGGAAAAAGATGGCTTGATCGCCATCGGCTCGGGTGGCC
CCTTCGCCCAGTCCGCCGCGACTGCCCTGCTGGATAATACCGATCTGCCAGCCCGAGACATCGTCGCCAAGGCGCTCACT
ATTGCCGGCGATATCTGTATTTACACCAATCACAACCACACCTTCGAAGAGCTGGACGGTTAA

Upstream 100 bases:

>100_bases
CCCCGCGTCGGCATTGGGCATCTGCCATCTCGCTTTCTCTCCTTGAAATCCCCCTGTTGCGCCCATACTTCCTTTGCTAC
GCGTAAAAAGGAGAATTCCC

Downstream 100 bases:

>100_bases
TCATGGCTTCCCTGACACCCAAAGACATTGTTTCCGAACTCAATCGCCACATCGTCGGTCAGGACGCGGCCAAGAGAGCC
GTGGCTCTGGCGCTACGCAC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MEQYRGTTIVSVRRGNNVVIGGDGQVSLGNTVMKGNARKVRRLFHGKVIAGFAGGTADAFTLFERFEAQLEKHQGHLVRA
AVELAKDWRTDRALRRLEALLAVADKESSLIITGNGDVIEPEKDGLIAIGSGGPFAQSAATALLDNTDLPARDIVAKALT
IAGDICIYTNHNHTFEELDG

Sequences:

>Translated_180_residues
MEQYRGTTIVSVRRGNNVVIGGDGQVSLGNTVMKGNARKVRRLFHGKVIAGFAGGTADAFTLFERFEAQLEKHQGHLVRA
AVELAKDWRTDRALRRLEALLAVADKESSLIITGNGDVIEPEKDGLIAIGSGGPFAQSAATALLDNTDLPARDIVAKALT
IAGDICIYTNHNHTFEELDG
>Mature_180_residues
MEQYRGTTIVSVRRGNNVVIGGDGQVSLGNTVMKGNARKVRRLFHGKVIAGFAGGTADAFTLFERFEAQLEKHQGHLVRA
AVELAKDWRTDRALRRLEALLAVADKESSLIITGNGDVIEPEKDGLIAIGSGGPFAQSAATALLDNTDLPARDIVAKALT
IAGDICIYTNHNHTFEELDG

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=78.4883720930232, Blast_Score=272, Evalue=7e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_ALCBS (Q0VMA6)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693964.1
- ProteinModelPortal:   Q0VMA6
- SMR:   Q0VMA6
- STRING:   Q0VMA6
- MEROPS:   T01.006
- GeneID:   4211336
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2244
- NMPDR:   fig|393595.12.peg.2244
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q0VMA6
- ProtClustDB:   PRK05456
- BioCyc:   ABOR393595:ABO_2244-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.- [C]

Molecular weight: Translated: 19325; Mature: 19325

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYRGTTIVSVRRGNNVVIGGDGQVSLGNTVMKGNARKVRRLFHGKVIAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEECCEEEECCHHHHHHHHCCCEEEEECCCCHHHH
TLFERFEAQLEKHQGHLVRAAVELAKDWRTDRALRRLEALLAVADKESSLIITGNGDVIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PEKDGLIAIGSGGPFAQSAATALLDNTDLPARDIVAKALTIAGDICIYTNHNHTFEELDG
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHCCC
>Mature Secondary Structure
MEQYRGTTIVSVRRGNNVVIGGDGQVSLGNTVMKGNARKVRRLFHGKVIAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEECCEEEECCHHHHHHHHCCCEEEEECCCCHHHH
TLFERFEAQLEKHQGHLVRAAVELAKDWRTDRALRRLEALLAVADKESSLIITGNGDVIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PEKDGLIAIGSGGPFAQSAATALLDNTDLPARDIVAKALTIAGDICIYTNHNHTFEELDG
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA