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The map label for this gene is ectB [H]

Identifier: 110835012

GI number: 110835012

Start: 2456896

End: 2458215

Strand: Direct

Name: ectB [H]

Synonym: ABO_2151

Alternate gene names: 110835012

Gene position: 2456896-2458215 (Clockwise)

Preceding gene: 110835011

Following gene: 110835013

Centisome position: 78.74

GC content: 54.62

Gene sequence:

>1320_bases
ATGAATACAGGAACCATGGATACAGACATTTTTGAAAGCCACGAATCGGAAGTAATGAGTTATGCCCGTAGCTTCCCTGT
GGTATTCGACCAGGCTAAAGGCAGTTATCTGTACGACGAAAACGGCAAGGAGTACATCGACTTCTTGGCCGGCGCAGGCA
CCCTGAACTACGGTCATAACAACCCCGTTCTGAAAGAAAAGCTGATGGAATACATTCAGCGCGACGGCATCGTTCACGGC
CTGGACATGCACACTGCCGCCAAGCGGGAATTCATGGATACCTTCTATGAAACGATTCTAAAACCTCGTGACATGGATCA
CGTGATGCAATTCACCGGCCCCACCGGCACCAACGCGGTGGAAGCGGCATTGAAAATTGCCCGTAACATCAAGGGTCGCG
AGAACATCATCAGCTTCACCAACGGCTTCCACGGCGTAAGCTTGGGCGCTTTGGCTGCCACCGGTAACAGCCACCACCGC
GGCGTAGCGGGCGTCACCATGGGCGGCGTTACCCCCATGCCCTATGACGGTTACCTAGGCGATGCCTTCGACACCACCGA
GTACTTGGACAAAGTATTAGGCGACTCCTCCAGCGGTGTTGACCACCCTGCCGCTGTTATCGTCGAAACCGTTCAGGGCG
AAGGCGGCATCAACGCGGCCAGCTTCGACTGGTTGCGCAACCTGGAAAAAGTCTGCCGCAAGCACGACATGCTGCTGATT
CTGGATGATATCCAGGCTGGCTGTGGTCGTACCGGCTCTTTCTTCAGCTTTGATGATATCGGCATCAGCCCGGACATCAT
CACCCTGTCCAAATCCTTGAGCGGCTATGGCCTGCCCTTCGCCATGGTACTGATGAAGCCGGAACTAGATCTGTGGAAAC
CAGGTGAGCACAACGGTACCTTCCGTGGCCACAACTTGGCCTTCGTCACTGCCGCAGCAGCGCTGAACCACTACTGGCGC
GACGACAAGTTCGCCAAGGAAGTGCAGAAGAAAGCGGACATCATTACCGACCATTTCCGCGAAATCGCTAACAGTTACGA
CAGCCATTGGTTCTATCTCAATGGCCGCGGCATGATGCAAGGCCTGGTGGCTCGCGATGGCGAAGTCGCTGGCGAAATCA
CCAAAGCCTGCTTCAAACGCCAGTTGGTGATTGAGACATCCGGTGCCGATGACCAGGTTATTAAAACCCTGTGCCCACTG
ACGATTAGCGAAGAAGATTTGGTTCGCGCACTTGAGATTGTTAAAGAGAGCGTGGACGAAGTGATGACCGACCGCATCAA
ACGCGGTGAAGCACACTCAGTCGCCAGCATCACGGCCTAA

Upstream 100 bases:

>100_bases
CATAACGACGAATACCTGCTACGTATCGGCCCGTTCAATCGCGACGACGCGTAAACGCAGCCCGAACCAGCAACCCGAAT
TCAAGCGAGGACCAGGAATC

Downstream 100 bases:

>100_bases
GCGGTTCCCGCTCCCCTCAACAGGGGAGCGTTATTCCTTCCTCAATTTTTTAGCTCAGGAGTTATCCATGATCGTTCGCA
CTCTGGCTGAAGCCGAAAAG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNTGTMDTDIFESHESEVMSYARSFPVVFDQAKGSYLYDENGKEYIDFLAGAGTLNYGHNNPVLKEKLMEYIQRDGIVHG
LDMHTAAKREFMDTFYETILKPRDMDHVMQFTGPTGTNAVEAALKIARNIKGRENIISFTNGFHGVSLGALAATGNSHHR
GVAGVTMGGVTPMPYDGYLGDAFDTTEYLDKVLGDSSSGVDHPAAVIVETVQGEGGINAASFDWLRNLEKVCRKHDMLLI
LDDIQAGCGRTGSFFSFDDIGISPDIITLSKSLSGYGLPFAMVLMKPELDLWKPGEHNGTFRGHNLAFVTAAAALNHYWR
DDKFAKEVQKKADIITDHFREIANSYDSHWFYLNGRGMMQGLVARDGEVAGEITKACFKRQLVIETSGADDQVIKTLCPL
TISEEDLVRALEIVKESVDEVMTDRIKRGEAHSVASITA

Sequences:

>Translated_439_residues
MNTGTMDTDIFESHESEVMSYARSFPVVFDQAKGSYLYDENGKEYIDFLAGAGTLNYGHNNPVLKEKLMEYIQRDGIVHG
LDMHTAAKREFMDTFYETILKPRDMDHVMQFTGPTGTNAVEAALKIARNIKGRENIISFTNGFHGVSLGALAATGNSHHR
GVAGVTMGGVTPMPYDGYLGDAFDTTEYLDKVLGDSSSGVDHPAAVIVETVQGEGGINAASFDWLRNLEKVCRKHDMLLI
LDDIQAGCGRTGSFFSFDDIGISPDIITLSKSLSGYGLPFAMVLMKPELDLWKPGEHNGTFRGHNLAFVTAAAALNHYWR
DDKFAKEVQKKADIITDHFREIANSYDSHWFYLNGRGMMQGLVARDGEVAGEITKACFKRQLVIETSGADDQVIKTLCPL
TISEEDLVRALEIVKESVDEVMTDRIKRGEAHSVASITA
>Mature_439_residues
MNTGTMDTDIFESHESEVMSYARSFPVVFDQAKGSYLYDENGKEYIDFLAGAGTLNYGHNNPVLKEKLMEYIQRDGIVHG
LDMHTAAKREFMDTFYETILKPRDMDHVMQFTGPTGTNAVEAALKIARNIKGRENIISFTNGFHGVSLGALAATGNSHHR
GVAGVTMGGVTPMPYDGYLGDAFDTTEYLDKVLGDSSSGVDHPAAVIVETVQGEGGINAASFDWLRNLEKVCRKHDMLLI
LDDIQAGCGRTGSFFSFDDIGISPDIITLSKSLSGYGLPFAMVLMKPELDLWKPGEHNGTFRGHNLAFVTAAAALNHYWR
DDKFAKEVQKKADIITDHFREIANSYDSHWFYLNGRGMMQGLVARDGEVAGEITKACFKRQLVIETSGADDQVIKTLCPL
TISEEDLVRALEIVKESVDEVMTDRIKRGEAHSVASITA

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=428, Percent_Identity=26.8691588785047, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI284507298, Length=316, Percent_Identity=27.2151898734177, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI13994255, Length=459, Percent_Identity=22.8758169934641, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI188536080, Length=288, Percent_Identity=23.2638888888889, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679950, Length=288, Percent_Identity=23.2638888888889, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679946, Length=288, Percent_Identity=23.2638888888889, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=24.6511627906977, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=24.1217798594848, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI145693181, Length=397, Percent_Identity=29.4710327455919, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789016, Length=423, Percent_Identity=28.8416075650118, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789759, Length=344, Percent_Identity=30.5232558139535, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787560, Length=432, Percent_Identity=30.787037037037, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=29.040404040404, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1786991, Length=302, Percent_Identity=27.1523178807947, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786349, Length=303, Percent_Identity=28.3828382838284, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144271, Length=405, Percent_Identity=26.1728395061728, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=26.8518518518519, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=291, Percent_Identity=25.4295532646048, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=425, Percent_Identity=30.1176470588235, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=30.4245283018868, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321456, Length=373, Percent_Identity=23.5924932975871, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357415, Length=438, Percent_Identity=25.1141552511416, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=24.8322147651007, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356575, Length=442, Percent_Identity=22.8506787330317, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281366494, Length=284, Percent_Identity=22.887323943662, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24667139, Length=284, Percent_Identity=22.887323943662, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24667143, Length=284, Percent_Identity=22.887323943662, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 48360; Mature: 48360

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGTMDTDIFESHESEVMSYARSFPVVFDQAKGSYLYDENGKEYIDFLAGAGTLNYGHN
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHCCCEECCCCC
NPVLKEKLMEYIQRDGIVHGLDMHTAAKREFMDTFYETILKPRDMDHVMQFTGPTGTNAV
CCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHH
EAALKIARNIKGRENIISFTNGFHGVSLGALAATGNSHHRGVAGVTMGGVTPMPYDGYLG
HHHHHHHHHCCCHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCEEEECCCCCCCCCCCCC
DAFDTTEYLDKVLGDSSSGVDHPAAVIVETVQGEGGINAASFDWLRNLEKVCRKHDMLLI
CCCCHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEE
LDDIQAGCGRTGSFFSFDDIGISPDIITLSKSLSGYGLPFAMVLMKPELDLWKPGEHNGT
EECHHHCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC
FRGHNLAFVTAAAALNHYWRDDKFAKEVQKKADIITDHFREIANSYDSHWFYLNGRGMMQ
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
GLVARDGEVAGEITKACFKRQLVIETSGADDQVIKTLCPLTISEEDLVRALEIVKESVDE
HHHHCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VMTDRIKRGEAHSVASITA
HHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MNTGTMDTDIFESHESEVMSYARSFPVVFDQAKGSYLYDENGKEYIDFLAGAGTLNYGHN
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHCCCEECCCCC
NPVLKEKLMEYIQRDGIVHGLDMHTAAKREFMDTFYETILKPRDMDHVMQFTGPTGTNAV
CCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHH
EAALKIARNIKGRENIISFTNGFHGVSLGALAATGNSHHRGVAGVTMGGVTPMPYDGYLG
HHHHHHHHHCCCHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCEEEECCCCCCCCCCCCC
DAFDTTEYLDKVLGDSSSGVDHPAAVIVETVQGEGGINAASFDWLRNLEKVCRKHDMLLI
CCCCHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEE
LDDIQAGCGRTGSFFSFDDIGISPDIITLSKSLSGYGLPFAMVLMKPELDLWKPGEHNGT
EECHHHCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC
FRGHNLAFVTAAAALNHYWRDDKFAKEVQKKADIITDHFREIANSYDSHWFYLNGRGMMQ
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
GLVARDGEVAGEITKACFKRQLVIETSGADDQVIKTLCPLTISEEDLVRALEIVKESVDE
HHHHCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VMTDRIKRGEAHSVASITA
HHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]