Click here to switch to the map view.

The map label for this gene is atoS [C]

Identifier: 110636400

GI number: 110636400

Start: 4385342

End: 4386592

Strand: Reverse

Name: atoS [C]

Synonym: Meso_4076

Alternate gene names: 110636400

Gene position: 4386592-4385342 (Counterclockwise)

Preceding gene: 110636401

Following gene: 110636397

Centisome position: 99.41

GC content: 63.95

Gene sequence:

>1251_bases
TTGCTTGAAACCCGTCGGGCCGCCGAGAAGGCCAACGCCGAACTTCTCGAGCTCAACCGCACGCTGGAGGAGCGCATCGC
CGAAGCCGTCGAGGCCCGCATGAAGATTGAGGCCGCGCTCCGGCAGGCGCAGAAGATGGAGGCCGTCGGTCAGCTCACGG
GCGGTATTGCCCATGACTTCAACAATATGCTTGCGGTCATCATTTCCGCACTCAACCTCATCGAGCGCCGCGTCGCCCAA
GGGGAGGACTTCGCGGAATTTATCGAAGCCGCCAAGGACGGCGCGGCCAGGGCCGCCTCCCTTACCCAGCGCCTTCTCGC
CTTCTCGCGCCAGCAGGCCCTCTCGCCCGAGCCGCTCAACGCCAACCAGCTGGTTGCCGACATGTCGGAACTGCTCCGCC
GCTCTCTGGGCGAGACGGTGCGGCTTGAAACCGTGCTCGCCAGCGGGCTCTGGAGGGTGCATGCCGACAAGAACCTGCTC
GAAAACGCCATCTTAAACCTTGCCATCAATGCGCGGGACGCCATGCCCGAAGGCGGCCGGCTCACCATCGAGACCGCAAA
CCGCCACTTAGACGAGGCTTACGCAGCCGAGCACGATGCAGTGGCCGGCCAGTATGTGATGATCGCCGTTACCGACACGG
GAATTGGCATGACACCGGAGGTCATGGCCAAGGCGTTTGAACCTTTTTTCACCACCAAGGGGCCGGGCAAGGGCACGGGA
CTTGGCCTCAGCCAGGTCTTCGGCTTTGTGAAGCAGTCCGGCGGCCACATAAAGATTTATTCCGACCCCGGCCGGGGCAC
GTCGATCAAAATCTATCTGCCGCGCCTCTACGGGACGGGTGATGCGCCGAAGCGCGCCCGCGCCAAGAAGCTTGCCCGCG
GGGCTGTATCCGAGGTGGTGCTGGTTGTGGAGGACGATGAGCAGGTGCTGTCGCTCACCGCGCAGATGCTTCGCGACCTG
GGCTACGGTGTTATTGAGGCGGGGGACGGCGCGGAAGCGCTGGCCGCGCTGTCGGACAACCCGGAGATCCGCCTTCTCTT
CACCGATGTCGTGATGCCGGACATGAACGGCCGGCGGCTCGCCGAGGAGGCTCAAAGACGCCGGCCGGGCCTGAAGGTGC
TCTTCACGACGGGCTACACGCGCAATGGGGTGGTGCATGAGGGTGTGCTCGACCCGGGCGTAAACCTCTTGCAAAAGCCG
GCTTCACTCGAGCAGCTCGCGGCAAAGATAAGGATGGTGCTGGACGGCTAA

Upstream 100 bases:

>100_bases
CTCGTCAACGCTGTGGAGCGGCGTGACGATACCGGCAAGCTTCGCCTCATCCGTATCACCATTTTTCAACGCGTCCGACC
GCCGCCGCTACGAGCGCGAG

Downstream 100 bases:

>100_bases
CGAAGCCCGATTAGCGCCTGTTGCAATCCGGCTCCTTCAATAGTGGCGATTGTGAAAACCGCCCGGCTGCTCAATCCCCC
ATTTTAAGCGCCTGGATGAA

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MLETRRAAEKANAELLELNRTLEERIAEAVEARMKIEAALRQAQKMEAVGQLTGGIAHDFNNMLAVIISALNLIERRVAQ
GEDFAEFIEAAKDGAARAASLTQRLLAFSRQQALSPEPLNANQLVADMSELLRRSLGETVRLETVLASGLWRVHADKNLL
ENAILNLAINARDAMPEGGRLTIETANRHLDEAYAAEHDAVAGQYVMIAVTDTGIGMTPEVMAKAFEPFFTTKGPGKGTG
LGLSQVFGFVKQSGGHIKIYSDPGRGTSIKIYLPRLYGTGDAPKRARAKKLARGAVSEVVLVVEDDEQVLSLTAQMLRDL
GYGVIEAGDGAEALAALSDNPEIRLLFTDVVMPDMNGRRLAEEAQRRRPGLKVLFTTGYTRNGVVHEGVLDPGVNLLQKP
ASLEQLAAKIRMVLDG

Sequences:

>Translated_416_residues
MLETRRAAEKANAELLELNRTLEERIAEAVEARMKIEAALRQAQKMEAVGQLTGGIAHDFNNMLAVIISALNLIERRVAQ
GEDFAEFIEAAKDGAARAASLTQRLLAFSRQQALSPEPLNANQLVADMSELLRRSLGETVRLETVLASGLWRVHADKNLL
ENAILNLAINARDAMPEGGRLTIETANRHLDEAYAAEHDAVAGQYVMIAVTDTGIGMTPEVMAKAFEPFFTTKGPGKGTG
LGLSQVFGFVKQSGGHIKIYSDPGRGTSIKIYLPRLYGTGDAPKRARAKKLARGAVSEVVLVVEDDEQVLSLTAQMLRDL
GYGVIEAGDGAEALAALSDNPEIRLLFTDVVMPDMNGRRLAEEAQRRRPGLKVLFTTGYTRNGVVHEGVLDPGVNLLQKP
ASLEQLAAKIRMVLDG
>Mature_416_residues
MLETRRAAEKANAELLELNRTLEERIAEAVEARMKIEAALRQAQKMEAVGQLTGGIAHDFNNMLAVIISALNLIERRVAQ
GEDFAEFIEAAKDGAARAASLTQRLLAFSRQQALSPEPLNANQLVADMSELLRRSLGETVRLETVLASGLWRVHADKNLL
ENAILNLAINARDAMPEGGRLTIETANRHLDEAYAAEHDAVAGQYVMIAVTDTGIGMTPEVMAKAFEPFFTTKGPGKGTG
LGLSQVFGFVKQSGGHIKIYSDPGRGTSIKIYLPRLYGTGDAPKRARAKKLARGAVSEVVLVVEDDEQVLSLTAQMLRDL
GYGVIEAGDGAEALAALSDNPEIRLLFTDVVMPDMNGRRLAEEAQRRRPGLKVLFTTGYTRNGVVHEGVLDPGVNLLQKP
ASLEQLAAKIRMVLDG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=26.0162601626016, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=264, Percent_Identity=26.1363636363636, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=27.6859504132231, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=28.5171102661597, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=26.0223048327138, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=331, Percent_Identity=25.6797583081571, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=27.5423728813559, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45058; Mature: 45058

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETRRAAEKANAELLELNRTLEERIAEAVEARMKIEAALRQAQKMEAVGQLTGGIAHDF
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNMLAVIISALNLIERRVAQGEDFAEFIEAAKDGAARAASLTQRLLAFSRQQALSPEPLN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
ANQLVADMSELLRRSLGETVRLETVLASGLWRVHADKNLLENAILNLAINARDAMPEGGR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHEECCCHHHHHHHHHHEEEECCCCCCCCCE
LTIETANRHLDEAYAAEHDAVAGQYVMIAVTDTGIGMTPEVMAKAFEPFFTTKGPGKGTG
EEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCC
LGLSQVFGFVKQSGGHIKIYSDPGRGTSIKIYLPRLYGTGDAPKRARAKKLARGAVSEVV
CCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHEE
LVVEDDEQVLSLTAQMLRDLGYGVIEAGDGAEALAALSDNPEIRLLFTDVVMPDMNGRRL
EEECCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCEEEEEEEEECCCCCCHHH
AEEAQRRRPGLKVLFTTGYTRNGVVHEGVLDPGVNLLQKPASLEQLAAKIRMVLDG
HHHHHHCCCCCEEEEECCCCCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLETRRAAEKANAELLELNRTLEERIAEAVEARMKIEAALRQAQKMEAVGQLTGGIAHDF
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNMLAVIISALNLIERRVAQGEDFAEFIEAAKDGAARAASLTQRLLAFSRQQALSPEPLN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
ANQLVADMSELLRRSLGETVRLETVLASGLWRVHADKNLLENAILNLAINARDAMPEGGR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHEECCCHHHHHHHHHHEEEECCCCCCCCCE
LTIETANRHLDEAYAAEHDAVAGQYVMIAVTDTGIGMTPEVMAKAFEPFFTTKGPGKGTG
EEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCC
LGLSQVFGFVKQSGGHIKIYSDPGRGTSIKIYLPRLYGTGDAPKRARAKKLARGAVSEVV
CCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHEE
LVVEDDEQVLSLTAQMLRDLGYGVIEAGDGAEALAALSDNPEIRLLFTDVVMPDMNGRRL
EEECCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCEEEEEEEEECCCCCCHHH
AEEAQRRRPGLKVLFTTGYTRNGVVHEGVLDPGVNLLQKPASLEQLAAKIRMVLDG
HHHHHHCCCCCEEEEECCCCCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA