Click here to switch to the map view.

The map label for this gene is queC

Identifier: 110636377

GI number: 110636377

Start: 4360082

End: 4360780

Strand: Reverse

Name: queC

Synonym: Meso_4053

Alternate gene names: 110636377

Gene position: 4360780-4360082 (Counterclockwise)

Preceding gene: 110636379

Following gene: 110636376

Centisome position: 98.83

GC content: 61.09

Gene sequence:

>699_bases
GTGAAGACTTTCGTTATCTGCTCTGGCGGATTGGACTCGGTTTCGCTTGCCCACAAGGTGGCGGTCGAGAAAACCCTCGC
TGGTCTCATTTCCTTCGATTACGGCCAACGCCACAAAAAAGAACTCGATTTCGCCCGCGCCTGCGCGCAGCGGCTCGATG
TCAGGCATATGATCATCGATATTCGCGCCGTTGGTGAGGGGCTGGCCGGTTCGGCTCTGACAGACGAGATCGACGTGCCC
AACGGCCATTATGCCGAAGACACCATGCGGATCACCGTTGTGCCCAATCGCAACGCCATCATGCTGGCGATCGCCTTCGG
CGTAGCGGCAGCGCAAAACGCCGACGCGGTGGCAACGGCCGTACATGGCGGGGATCATTTCATCTATCCCGATTGCCGCC
CCGGTTTCATCGAGGCCTTTCAGGCGATGCAGGCGCAAGCTCTCGACGGCTACGCCAAGATTGCTCTTTACGCGCCTTAT
GTGAACCTTTCCAAGGCCAATATCGTCTCGGATGGGGTACGCCACCGCACCCCGTTCGAGGCGACGTGGTCGTGCTATAA
AGGCGGCAAGCATCACTGCGGCCGCTGCGGCACCTGCGTTGAGCGCCGCGAGGCGTTCGATCTCGCCGGCGTCACCGATC
CCACCACATATGAGGACGCTGCGTTCTGGCGCGAGGCCGTCGCGAGGAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGGCACTCTCCCGGTTCACAAGCAAAGCCACATGGGCTAGGGGGAGGGCAGAGAAATCTCCGGTCGCAGCCTACCCGGT
AAAAACAAGGACCCTGCTCT

Downstream 100 bases:

>100_bases
TGTTTAGGATCACCAAGCAGTTCCACTTTTCGGCGTCACACCAACTGTTGCGATTGGCCGACGATCATCCTTGCAAGCGT
CTGCACGGCCACAATTATAT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKTFVICSGGLDSVSLAHKVAVEKTLAGLISFDYGQRHKKELDFARACAQRLDVRHMIIDIRAVGEGLAGSALTDEIDVP
NGHYAEDTMRITVVPNRNAIMLAIAFGVAAAQNADAVATAVHGGDHFIYPDCRPGFIEAFQAMQAQALDGYAKIALYAPY
VNLSKANIVSDGVRHRTPFEATWSCYKGGKHHCGRCGTCVERREAFDLAGVTDPTTYEDAAFWREAVARKAG

Sequences:

>Translated_232_residues
MKTFVICSGGLDSVSLAHKVAVEKTLAGLISFDYGQRHKKELDFARACAQRLDVRHMIIDIRAVGEGLAGSALTDEIDVP
NGHYAEDTMRITVVPNRNAIMLAIAFGVAAAQNADAVATAVHGGDHFIYPDCRPGFIEAFQAMQAQALDGYAKIALYAPY
VNLSKANIVSDGVRHRTPFEATWSCYKGGKHHCGRCGTCVERREAFDLAGVTDPTTYEDAAFWREAVARKAG
>Mature_232_residues
MKTFVICSGGLDSVSLAHKVAVEKTLAGLISFDYGQRHKKELDFARACAQRLDVRHMIIDIRAVGEGLAGSALTDEIDVP
NGHYAEDTMRITVVPNRNAIMLAIAFGVAAAQNADAVATAVHGGDHFIYPDCRPGFIEAFQAMQAQALDGYAKIALYAPY
VNLSKANIVSDGVRHRTPFEATWSCYKGGKHHCGRCGTCVERREAFDLAGVTDPTTYEDAAFWREAVARKAG

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=225, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_MESSB (Q11B05)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676585.1
- ProteinModelPortal:   Q11B05
- SMR:   Q11B05
- STRING:   Q11B05
- GeneID:   4181315
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_4053
- NMPDR:   fig|266779.1.peg.3009
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q11B05
- ProtClustDB:   CLSK864390
- BioCyc:   MSP266779:MESO_4053-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25136; Mature: 25136

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFVICSGGLDSVSLAHKVAVEKTLAGLISFDYGQRHKKELDFARACAQRLDVRHMIID
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHEEE
IRAVGEGLAGSALTDEIDVPNGHYAEDTMRITVVPNRNAIMLAIAFGVAAAQNADAVATA
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEHHHHCCCCCCEEEE
VHGGDHFIYPDCRPGFIEAFQAMQAQALDGYAKIALYAPYVNLSKANIVSDGVRHRTPFE
EECCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCH
ATWSCYKGGKHHCGRCGTCVERREAFDLAGVTDPTTYEDAAFWREAVARKAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTFVICSGGLDSVSLAHKVAVEKTLAGLISFDYGQRHKKELDFARACAQRLDVRHMIID
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHEEE
IRAVGEGLAGSALTDEIDVPNGHYAEDTMRITVVPNRNAIMLAIAFGVAAAQNADAVATA
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEHHHHCCCCCCEEEE
VHGGDHFIYPDCRPGFIEAFQAMQAQALDGYAKIALYAPYVNLSKANIVSDGVRHRTPFE
EECCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCH
ATWSCYKGGKHHCGRCGTCVERREAFDLAGVTDPTTYEDAAFWREAVARKAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA