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The map label for this gene is ttuA [H]

Identifier: 110636186

GI number: 110636186

Start: 4163159

End: 4164184

Strand: Reverse

Name: ttuA [H]

Synonym: Meso_3862

Alternate gene names: 110636186

Gene position: 4164184-4163159 (Counterclockwise)

Preceding gene: 110636189

Following gene: 110636157

Centisome position: 94.37

GC content: 62.96

Gene sequence:

>1026_bases
ATGAATGATGACCGGCGCGGGTGGCATATGCAGGTCGGGAACCAAGGTCATACTGATGAGAGCCCGCCACTCGATCTCCG
GGCGCTTCGCTACGTGCTGGCAGCAGCCGAATATCTGAGCTTTCGTCGCGCCGCTGAAGCTCTCGACGCACATCCGTCGA
GCGTCAGCAGGGGCGTGAGGGACTTGGAGGACGAAATCGGCGTCGCGCTTTTTGAAAGAGGCGCGTCAGGCGTTCGACTG
ACGGACGCTGGCGCGCGCTTTCTCGATCAGGTGGTCCCGGCGGTGAGACAGATCGGATCGGCGTTTCGAACGGCGGGCGC
TGCCGGCCGGGTGGCGTCCGGCACCGTGCGGGTTGGCATCATCGTCTCGATAGCGGGCGGGTTCATGCGGAACCTCTTGC
TTGACTACTCGTCCAAGCATCCGGAGGTGGCGGTCGAAGTCTACGATGGCGGTCGCCGGGAACACGTCACGGCCCTGCGG
TCGCGGCAGCTCGATGTTGCCTTCTTTTCTGGAAGCGGCGAGATTCCCGATTGTGAGATCGCGGAGTTGTGGCACGAACG
TGTCCACGTTGCGGTTCCGGTCAGCCATCCCCTTGCGAACTTAGAGCGCGTCGATTGGCCGATGCTCCGGGACGAGCAAT
TCATCGTAACCAGACGTGAGCCAGGTCCCGAGGTTCATGACTACATCGTGCGTCGGGTGGCCGACTTCAGCACATATCCG
CGGGTGGAGCGCAAGCCCTGCACTCAGGAGACGCTGATGAGCCTTGTCGCACTCGGCCAAGGCATCACCCTGGTCTCCTC
GGTATGGACTGAGGTGCGCATGCCCGGCCTCGTCTTTCGTCCCCTCACAGCATGCGAGGATGTCGTTCCGTTCAGCGCGG
TATGGTCGCCGGACAATGACAATCCCGCTCTTCGCCGATTCGTCTCGGTCGCCTACCTTCTTGCCGGCCGGTCGCGCCAC
GGCAAGGCGCTTACTGTTCGAGCGCAACGCCCGAACGGCGGCGGACGAGATCGCTTCGAGTCCTAA

Upstream 100 bases:

>100_bases
ATAGCTTTGCGGACAATCCTCCCGAGCGCGTGTCGAAAGCTGACCTCCCTTTGCTGTGGCGGCCGTTTGGCGGATCTGCG
TCAAAAACGGAGGCAACCGC

Downstream 100 bases:

>100_bases
CCGAGGCCCTCGGGAAACAGGTTCGATGCGCTCACGCGCCCGGTTCGTGTCGGCGCGCCGGGTCGGCAACGGTCTTCAAA
CGATTGTCGGTGCGGTCCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Tartrate utilization transcriptional regulator [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNDDRRGWHMQVGNQGHTDESPPLDLRALRYVLAAAEYLSFRRAAEALDAHPSSVSRGVRDLEDEIGVALFERGASGVRL
TDAGARFLDQVVPAVRQIGSAFRTAGAAGRVASGTVRVGIIVSIAGGFMRNLLLDYSSKHPEVAVEVYDGGRREHVTALR
SRQLDVAFFSGSGEIPDCEIAELWHERVHVAVPVSHPLANLERVDWPMLRDEQFIVTRREPGPEVHDYIVRRVADFSTYP
RVERKPCTQETLMSLVALGQGITLVSSVWTEVRMPGLVFRPLTACEDVVPFSAVWSPDNDNPALRRFVSVAYLLAGRSRH
GKALTVRAQRPNGGGRDRFES

Sequences:

>Translated_341_residues
MNDDRRGWHMQVGNQGHTDESPPLDLRALRYVLAAAEYLSFRRAAEALDAHPSSVSRGVRDLEDEIGVALFERGASGVRL
TDAGARFLDQVVPAVRQIGSAFRTAGAAGRVASGTVRVGIIVSIAGGFMRNLLLDYSSKHPEVAVEVYDGGRREHVTALR
SRQLDVAFFSGSGEIPDCEIAELWHERVHVAVPVSHPLANLERVDWPMLRDEQFIVTRREPGPEVHDYIVRRVADFSTYP
RVERKPCTQETLMSLVALGQGITLVSSVWTEVRMPGLVFRPLTACEDVVPFSAVWSPDNDNPALRRFVSVAYLLAGRSRH
GKALTVRAQRPNGGGRDRFES
>Mature_341_residues
MNDDRRGWHMQVGNQGHTDESPPLDLRALRYVLAAAEYLSFRRAAEALDAHPSSVSRGVRDLEDEIGVALFERGASGVRL
TDAGARFLDQVVPAVRQIGSAFRTAGAAGRVASGTVRVGIIVSIAGGFMRNLLLDYSSKHPEVAVEVYDGGRREHVTALR
SRQLDVAFFSGSGEIPDCEIAELWHERVHVAVPVSHPLANLERVDWPMLRDEQFIVTRREPGPEVHDYIVRRVADFSTYP
RVERKPCTQETLMSLVALGQGITLVSSVWTEVRMPGLVFRPLTACEDVVPFSAVWSPDNDNPALRRFVSVAYLLAGRSRH
GKALTVRAQRPNGGGRDRFES

Specific function: Transcriptional regulator of the ttuABCDE tartrate utilization operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=29.0076335877863, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=26.4808362369338, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=28.0821917808219, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=27.5, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI157672245, Length=194, Percent_Identity=28.8659793814433, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=29.3103448275862, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081904, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=22.8571428571429, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=25.2, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693105, Length=211, Percent_Identity=21.8009478672986, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37701; Mature: 37701

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDRRGWHMQVGNQGHTDESPPLDLRALRYVLAAAEYLSFRRAAEALDAHPSSVSRGVR
CCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DLEDEIGVALFERGASGVRLTDAGARFLDQVVPAVRQIGSAFRTAGAAGRVASGTVRVGI
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
IVSIAGGFMRNLLLDYSSKHPEVAVEVYDGGRREHVTALRSRQLDVAFFSGSGEIPDCEI
EEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHH
AELWHERVHVAVPVSHPLANLERVDWPMLRDEQFIVTRREPGPEVHDYIVRRVADFSTYP
HHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
RVERKPCTQETLMSLVALGQGITLVSSVWTEVRMPGLVFRPLTACEDVVPFSAVWSPDND
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCEEECCCCC
NPALRRFVSVAYLLAGRSRHGKALTVRAQRPNGGGRDRFES
CHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNDDRRGWHMQVGNQGHTDESPPLDLRALRYVLAAAEYLSFRRAAEALDAHPSSVSRGVR
CCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DLEDEIGVALFERGASGVRLTDAGARFLDQVVPAVRQIGSAFRTAGAAGRVASGTVRVGI
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
IVSIAGGFMRNLLLDYSSKHPEVAVEVYDGGRREHVTALRSRQLDVAFFSGSGEIPDCEI
EEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHH
AELWHERVHVAVPVSHPLANLERVDWPMLRDEQFIVTRREPGPEVHDYIVRRVADFSTYP
HHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
RVERKPCTQETLMSLVALGQGITLVSSVWTEVRMPGLVFRPLTACEDVVPFSAVWSPDND
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCEEECCCCC
NPALRRFVSVAYLLAGRSRHGKALTVRAQRPNGGGRDRFES
CHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]