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The map label for this gene is glyQ

Identifier: 110633070

GI number: 110633070

Start: 786632

End: 787588

Strand: Direct

Name: glyQ

Synonym: Meso_0713

Alternate gene names: 110633070

Gene position: 786632-787588 (Clockwise)

Preceding gene: 110633069

Following gene: 110633071

Centisome position: 17.83

GC content: 62.17

Gene sequence:

>957_bases
GTGAACGCCAGCGCCCTTCCGCACATGCATCCCTCCAGGTCCTTCCAGGGCCTGATCCTGACGCTGCACAGCTATTGGGC
GGCGCAGGGCTGCGTCATCCTCCAGCCCTATGACATGGAGGTGGGCGCGGGCACCTTCCATCCGGCGACCACGCTCCGCT
CCCTGGGGCCGCGCCCGTGGAACGCGGCCTATGTGCAGCCTTCGCGCCGGCCGAAGGACGGTCGCTACGGTGAAAACCCG
AACAGGCTGCAGCATTATTACCAATATCAGGTGATCCTGAAGCCCAACCCGCCCAACCTGCAGGAGCTCTATCTGGGCTC
GCTTGCCGCCATCGGGCTGGACCCCCTGCTGCACGACATCCGCTTTGTGGAGGACGACTGGGAAAGCCCCACGCTCGGCG
CCTGGGGGCTCGGCTGGGAGTGCTGGTGCGACGGCATGGAGGTTTCCCAGTTCACCTACTTCCAGCAGGTCTGCGGCATC
GAATGCGCCCCAGTTTCCGGCGAGCTGACATATGGGCTCGAGCGGCTGGCCATGTATGTGCAGGGCGTCGACAATGTCTA
CGATCTGAATTTCAACGGGCTCGAAGGCTCGGACAAAGTCACCTATGGCGAGGTTTTCCTGCAGGCCGAGCAGGAATATT
CGCGGCATAATTTCGAATATGCGAATACCGAAATGCTTTTCCGCCACTTTGAGGATGCGGAGCGGGAATGCCGTGCGCTT
CTTGAAGCCGGCGCGCCACGCCCTAGCGACAATGCCGCGCTACATCGCATGGTCTTCCCGGCCTACGACCAGTGCATCAA
GGCTTCCCACGTCTTCAATCTTCTGGATGCTCGCGGCGTAATCTCGGTTACGGAGCGGCAGAGCTATATCCTGCGCGTCC
GCGATCTGGCGAAAGCCTGCGGCGAAGCTTTTCTCAACACCGAGGCAGGCGGGGCCACATTGGCGACTGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCGAAGGGCTCGGCTTCACAAGTGAAGGCGTCACTCGCTTGACGCCTGACCAACCCCGCAATAGGACGGGCCGAGCC
AAAGCCCTCGGAGAAGCCGC

Downstream 100 bases:

>100_bases
ACGACAGCTTCCTACGAGTCGGGGCAGAAATAGAAGGCGGGCGCGGAAAACCCTTCCGACTTGCCTTTCCCGGCCGTCGT
CTCGATAGCCCGCCGCACGC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNASALPHMHPSRSFQGLILTLHSYWAAQGCVILQPYDMEVGAGTFHPATTLRSLGPRPWNAAYVQPSRRPKDGRYGENP
NRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGI
ECAPVSGELTYGLERLAMYVQGVDNVYDLNFNGLEGSDKVTYGEVFLQAEQEYSRHNFEYANTEMLFRHFEDAERECRAL
LEAGAPRPSDNAALHRMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRDLAKACGEAFLNTEAGGATLATAA

Sequences:

>Translated_318_residues
MNASALPHMHPSRSFQGLILTLHSYWAAQGCVILQPYDMEVGAGTFHPATTLRSLGPRPWNAAYVQPSRRPKDGRYGENP
NRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGI
ECAPVSGELTYGLERLAMYVQGVDNVYDLNFNGLEGSDKVTYGEVFLQAEQEYSRHNFEYANTEMLFRHFEDAERECRAL
LEAGAPRPSDNAALHRMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRDLAKACGEAFLNTEAGGATLATAA
>Mature_318_residues
MNASALPHMHPSRSFQGLILTLHSYWAAQGCVILQPYDMEVGAGTFHPATTLRSLGPRPWNAAYVQPSRRPKDGRYGENP
NRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGI
ECAPVSGELTYGLERLAMYVQGVDNVYDLNFNGLEGSDKVTYGEVFLQAEQEYSRHNFEYANTEMLFRHFEDAERECRAL
LEAGAPRPSDNAALHRMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRDLAKACGEAFLNTEAGGATLATAA

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=65.9863945578231, Blast_Score=401, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_MESSB (Q11KG2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673278.1
- STRING:   Q11KG2
- GeneID:   4180191
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0713
- NMPDR:   fig|266779.1.peg.2850
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- PhylomeDB:   Q11KG2
- ProtClustDB:   PRK09348
- BioCyc:   MSP266779:MESO_0713-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 35697; Mature: 35697

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASALPHMHPSRSFQGLILTLHSYWAAQGCVILQPYDMEVGAGTFHPATTLRSLGPRPW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCC
NAAYVQPSRRPKDGRYGENPNRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDI
CCEEECCCCCCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
RFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECAPVSGELTYGLERLAMYV
HHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHH
QGVDNVYDLNFNGLEGSDKVTYGEVFLQAEQEYSRHNFEYANTEMLFRHFEDAERECRAL
HCCCCEEECCCCCCCCCCCEEHHHHHEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LEAGAPRPSDNAALHRMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRDLAKAC
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
GEAFLNTEAGGATLATAA
HHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MNASALPHMHPSRSFQGLILTLHSYWAAQGCVILQPYDMEVGAGTFHPATTLRSLGPRPW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCC
NAAYVQPSRRPKDGRYGENPNRLQHYYQYQVILKPNPPNLQELYLGSLAAIGLDPLLHDI
CCEEECCCCCCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
RFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECAPVSGELTYGLERLAMYV
HHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHH
QGVDNVYDLNFNGLEGSDKVTYGEVFLQAEQEYSRHNFEYANTEMLFRHFEDAERECRAL
HCCCCEEECCCCCCCCCCCEEHHHHHEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LEAGAPRPSDNAALHRMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRDLAKAC
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
GEAFLNTEAGGATLATAA
HHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA