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The map label for this gene is pkn1 [H]

Identifier: 110632934

GI number: 110632934

Start: 636357

End: 637073

Strand: Direct

Name: pkn1 [H]

Synonym: Meso_0576

Alternate gene names: 110632934

Gene position: 636357-637073 (Clockwise)

Preceding gene: 110632933

Following gene: 110632935

Centisome position: 14.42

GC content: 64.85

Gene sequence:

>717_bases
GTGGGCGGTCGACTCGGAAGCAAAGCCCTGCTGGTGATCGGCATCATTGTTGGCATTGGATCACCGGCGCGGTCGGAAGA
CGGCGAACGTGTCACGATCGGCGCGTTCGAAATCGATGCGACCGAGGTCACAATCCGGCAGTTCCGCGAATTTGCCGATG
CGACCGGGCTCGAGACCGCAGCCGAGAAATCCGGCGGCGGCTTCGAATGGGGCTCGGGTTGGGAGCGCCGGTCCGGGTGG
ATCGTCTATCGCCCGTTCGGCGCTGAACCGGCCTCACTCGATGAGCCTGCCGTGCATGTGAGCTGGGAAGAGGCGTCCGC
CTATTGCCGCTGGCGGGGCGGCCGACTCCCAACTGCACAGGAGTGGCGCCTTGCCGCCTACACAGAAACGCGATCGTCGG
TGGCCGGCTTCGAGACCGGCCGAACTTATCGCTTTCCCTCCGGCGAAACCGCGGAGGGCATGAACACGCGGGAGGACGAT
CCTTGGCCGCGCCATGCGCCGGTCGGATCGACGCCTCCAGGTGTCAACGGCCTCCACGACATGGGAGGGAATGTCTGGGA
ATGGATCGCGGATCGGCAGGGTGACGAGGCACTCACCGCTGGGGGCTCGTGGTGGTACGGCAGCGAACAGGCGACAGCCG
AGGCCATGCAGTGGAAGCCATCTGATTTCTACGCAGTCTATGTCGGGTTCCGCTGTGTATACCCGCCCCCTTCATGA

Upstream 100 bases:

>100_bases
TGGAAGGGATCGAGGGATTTGGCGCCACGCTACGTCAGCCGCCGTATCCGGGAAAGAACTATGGCGGGGTCGTCACCTGG
CCATTCAGGAGGACCTGAAG

Downstream 100 bases:

>100_bases
TCTGGCGGCCGGACGCCGAATCTCGCGCTCGACTTGATGCCACGATGCAACCCATCGTGCAGGAGTAGCCAAATGGATGA
GGAATCCGGCCGCACCGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MGGRLGSKALLVIGIIVGIGSPARSEDGERVTIGAFEIDATEVTIRQFREFADATGLETAAEKSGGGFEWGSGWERRSGW
IVYRPFGAEPASLDEPAVHVSWEEASAYCRWRGGRLPTAQEWRLAAYTETRSSVAGFETGRTYRFPSGETAEGMNTREDD
PWPRHAPVGSTPPGVNGLHDMGGNVWEWIADRQGDEALTAGGSWWYGSEQATAEAMQWKPSDFYAVYVGFRCVYPPPS

Sequences:

>Translated_238_residues
MGGRLGSKALLVIGIIVGIGSPARSEDGERVTIGAFEIDATEVTIRQFREFADATGLETAAEKSGGGFEWGSGWERRSGW
IVYRPFGAEPASLDEPAVHVSWEEASAYCRWRGGRLPTAQEWRLAAYTETRSSVAGFETGRTYRFPSGETAEGMNTREDD
PWPRHAPVGSTPPGVNGLHDMGGNVWEWIADRQGDEALTAGGSWWYGSEQATAEAMQWKPSDFYAVYVGFRCVYPPPS
>Mature_237_residues
GGRLGSKALLVIGIIVGIGSPARSEDGERVTIGAFEIDATEVTIRQFREFADATGLETAAEKSGGGFEWGSGWERRSGWI
VYRPFGAEPASLDEPAVHVSWEEASAYCRWRGGRLPTAQEWRLAAYTETRSSVAGFETGRTYRFPSGETAEGMNTREDDP
WPRHAPVGSTPPGVNGLHDMGGNVWEWIADRQGDEALTAGGSWWYGSEQATAEAMQWKPSDFYAVYVGFRCVYPPPS

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=248, Percent_Identity=33.0645161290323, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI257470977, Length=265, Percent_Identity=30.188679245283, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI38202250, Length=281, Percent_Identity=29.8932384341637, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI194248088, Length=261, Percent_Identity=31.8007662835249, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI257470975, Length=260, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI226437577, Length=159, Percent_Identity=34.5911949685535, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI194248090, Length=171, Percent_Identity=33.9181286549708, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130397, Length=205, Percent_Identity=30.2439024390244, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 26033; Mature: 25902

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRLGSKALLVIGIIVGIGSPARSEDGERVTIGAFEIDATEVTIRQFREFADATGLETA
CCCCCCCHHHEEHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCCHH
AEKSGGGFEWGSGWERRSGWIVYRPFGAEPASLDEPAVHVSWEEASAYCRWRGGRLPTAQ
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHCCCEEEECCCCCCCCC
EWRLAAYTETRSSVAGFETGRTYRFPSGETAEGMNTREDDPWPRHAPVGSTPPGVNGLHD
CCEEEEEHHCHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
MGGNVWEWIADRQGDEALTAGGSWWYGSEQATAEAMQWKPSDFYAVYVGFRCVYPPPS
CCCHHHHHHHCCCCCCEEECCCCEEECCCHHHHHHHCCCCCCEEEEEEEEEEECCCCC
>Mature Secondary Structure 
GGRLGSKALLVIGIIVGIGSPARSEDGERVTIGAFEIDATEVTIRQFREFADATGLETA
CCCCCCHHHEEHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCCHH
AEKSGGGFEWGSGWERRSGWIVYRPFGAEPASLDEPAVHVSWEEASAYCRWRGGRLPTAQ
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHCCCEEEECCCCCCCCC
EWRLAAYTETRSSVAGFETGRTYRFPSGETAEGMNTREDDPWPRHAPVGSTPPGVNGLHD
CCEEEEEHHCHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
MGGNVWEWIADRQGDEALTAGGSWWYGSEQATAEAMQWKPSDFYAVYVGFRCVYPPPS
CCCHHHHHHHCCCCCCEEECCCCEEECCCHHHHHHHCCCCCCEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]