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The map label for this gene is yciL [C]

Identifier: 110632789

GI number: 110632789

Start: 473318

End: 474718

Strand: Direct

Name: yciL [C]

Synonym: Meso_0428

Alternate gene names: 110632789

Gene position: 473318-474718 (Clockwise)

Preceding gene: 110632787

Following gene: 110632790

Centisome position: 10.73

GC content: 64.6

Gene sequence:

>1401_bases
ATGAAGAATAGAAAAGACAAATCGGAAAAAGCTACCGCTCCACGTGGAAAGCCGGCGGGCAAGGCCGCTGCCGGAGGCGC
TCCCCGTGGCAAATACGGCAAGGCGGCAAAGGACGAAATTCGGGAAGACGGCCGCACGGATGGCGAGCGCATCGCCAAAC
GCCTTGCGCGTGCCGGGCTGGCCTCCAGGCGCGATGCGGAGGCGATGATCGAGGCAGGCAGGGTGAAGGTGAACGGACGT
GTGCTTTCCTCGCCCGCATTCAACGTGCGCCCATCGGACAGGATAGAAGTCGACGACGAGCCTCTTCCCGCCGCCGAACG
CACGCGGCTTTTTCTTTTCCACAAACCCGCCGGCGTGGTCACCACAACGCGCGACCCGGAGGGCCGCCGGACGATTTTCG
ACACCCTGCCGGAAGGCCTGCCGCGGCTGATTACCGTGGGCCGCCTGGATATAAACACGGAAGGCCTCATCCTGCTTACC
AATGACGGAGGGCTCGCGCGCGCACTCGAACTGCCGTCCACAGGCTGGCTCCGGCGCTATCGCGTGCGCGTGCATGGCAA
GGTCGATCCGAAGGCGCTGGCGGAGCTGGAAAAGGGCATAGCGGTCGACGGCGTGTTCTACGGCGCAATCACCGCCAGCC
TGGATCGTCAGCAGGGCAGCAATGCCTGGCTGACGCTGGGCCTCCGCGAGGGCAAGAACCGTGAGGTGAAGAATGTCCTC
GGCGCGCTTGGCCTGGAGGTGACCAGGCTGATCCGCGTTTCCTATGGCCCGTTCCAACTCGGCGACCTGCCAGAGGGCGC
CGTGCTGGAAGTGAAAGGCCGCACATTGCGCGACCAGCTTGGCGAGCGGTTGATCGAGCAGGCAGGCGCCGATTTCGAGG
CGCCGATTGCAATACCCTTTGCCAACAAGCCCGTGCGCGCCGAACGCAGGAAGCCCGAGGAAGAAAAGCGCAAGACCGGC
TTAGAGGAAAATGCGGGGCGGCAGGAAAGAAAGCCGGCGAACCGCAGGAAGTCACGAGAGGAAAAGCACGAGGAAGCCCG
CGACAGGCTGCAGACAAAGCGGCCGGACGACTTCAAAGGAAAAGGCAGCGCTGCTCACAAAGGCAAGGACCAGCGTCCGC
CGCGTATCTCCAAAACTGCTCGGCCGGAAAAATCCGGCCAGGAGCGGATGTCAGGGGATTCCAAGGCGGAGGGTCCGACG
CGCGCACCCGTTGAACGGCGTTCCCGTGCCTCCAATGTCTGGATGGCGCCAGGCGCTCGGCCGGTAGGGAAGAAGCGCGC
CGAGGAAGCCTCCAAAGATGCCGAGAAGAAACCGCGCGCGGGCCGTCCGGCAACCGGTCGTGCGGAAAGACGTGACGGGG
ATCGGCCGACGCGCCCCGGCAAGGGACGGAGGGAACGCTGA

Upstream 100 bases:

>100_bases
TGAAACTCGCCGTAGCCTTCGGCCGTTGCTGTTCCAATCTTTTTGCTCGCAACGCTGATGACGAATTGATACCTAGCCGG
TCCAAGAGGCTCGGGCCAGC

Downstream 100 bases:

>100_bases
GATCCGGCATGCGCGAGGCGGCGGTTGGAAGTAAGGTTTCCCATGGGAGTGGCGTGTAATGCGCATCGTCGGCGGCGCGC
TGCGTGGCAGGCAGCTCACT

Product: pseudouridine synthase, Rsu

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKNRKDKSEKATAPRGKPAGKAAAGGAPRGKYGKAAKDEIREDGRTDGERIAKRLARAGLASRRDAEAMIEAGRVKVNGR
VLSSPAFNVRPSDRIEVDDEPLPAAERTRLFLFHKPAGVVTTTRDPEGRRTIFDTLPEGLPRLITVGRLDINTEGLILLT
NDGGLARALELPSTGWLRRYRVRVHGKVDPKALAELEKGIAVDGVFYGAITASLDRQQGSNAWLTLGLREGKNREVKNVL
GALGLEVTRLIRVSYGPFQLGDLPEGAVLEVKGRTLRDQLGERLIEQAGADFEAPIAIPFANKPVRAERRKPEEEKRKTG
LEENAGRQERKPANRRKSREEKHEEARDRLQTKRPDDFKGKGSAAHKGKDQRPPRISKTARPEKSGQERMSGDSKAEGPT
RAPVERRSRASNVWMAPGARPVGKKRAEEASKDAEKKPRAGRPATGRAERRDGDRPTRPGKGRRER

Sequences:

>Translated_466_residues
MKNRKDKSEKATAPRGKPAGKAAAGGAPRGKYGKAAKDEIREDGRTDGERIAKRLARAGLASRRDAEAMIEAGRVKVNGR
VLSSPAFNVRPSDRIEVDDEPLPAAERTRLFLFHKPAGVVTTTRDPEGRRTIFDTLPEGLPRLITVGRLDINTEGLILLT
NDGGLARALELPSTGWLRRYRVRVHGKVDPKALAELEKGIAVDGVFYGAITASLDRQQGSNAWLTLGLREGKNREVKNVL
GALGLEVTRLIRVSYGPFQLGDLPEGAVLEVKGRTLRDQLGERLIEQAGADFEAPIAIPFANKPVRAERRKPEEEKRKTG
LEENAGRQERKPANRRKSREEKHEEARDRLQTKRPDDFKGKGSAAHKGKDQRPPRISKTARPEKSGQERMSGDSKAEGPT
RAPVERRSRASNVWMAPGARPVGKKRAEEASKDAEKKPRAGRPATGRAERRDGDRPTRPGKGRRER
>Mature_466_residues
MKNRKDKSEKATAPRGKPAGKAAAGGAPRGKYGKAAKDEIREDGRTDGERIAKRLARAGLASRRDAEAMIEAGRVKVNGR
VLSSPAFNVRPSDRIEVDDEPLPAAERTRLFLFHKPAGVVTTTRDPEGRRTIFDTLPEGLPRLITVGRLDINTEGLILLT
NDGGLARALELPSTGWLRRYRVRVHGKVDPKALAELEKGIAVDGVFYGAITASLDRQQGSNAWLTLGLREGKNREVKNVL
GALGLEVTRLIRVSYGPFQLGDLPEGAVLEVKGRTLRDQLGERLIEQAGADFEAPIAIPFANKPVRAERRKPEEEKRKTG
LEENAGRQERKPANRRKSREEKHEEARDRLQTKRPDDFKGKGSAAHKGKDQRPPRISKTARPEKSGQERMSGDSKAEGPT
RAPVERRSRASNVWMAPGARPVGKKRAEEASKDAEKKPRAGRPATGRAERRDGDRPTRPGKGRRER

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=230, Percent_Identity=41.7391304347826, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790453, Length=292, Percent_Identity=26.3698630136986, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=32.0652173913043, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788510, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 51402; Mature: 51402

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRKDKSEKATAPRGKPAGKAAAGGAPRGKYGKAAKDEIREDGRTDGERIAKRLARAGL
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
ASRRDAEAMIEAGRVKVNGRVLSSPAFNVRPSDRIEVDDEPLPAAERTRLFLFHKPAGVV
CCCCHHHHHHHCCEEEECCEEECCCCCCCCCCCCEECCCCCCCCHHCCEEEEEECCCCEE
TTTRDPEGRRTIFDTLPEGLPRLITVGRLDINTEGLILLTNDGGLARALELPSTGWLRRY
EECCCCCCCHHHHHHHHHHHHHHEEECEEEECCCCEEEEECCCCCEEEEECCCCHHHEEE
RVRVHGKVDPKALAELEKGIAVDGVFYGAITASLDRQQGSNAWLTLGLREGKNREVKNVL
EEEECCCCCHHHHHHHHHCCEECHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
GALGLEVTRLIRVSYGPFQLGDLPEGAVLEVKGRTLRDQLGERLIEQAGADFEAPIAIPF
HHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECC
ANKPVRAERRKPEEEKRKTGLEENAGRQERKPANRRKSREEKHEEARDRLQTKRPDDFKG
CCCCCCHHHCCCHHHHHHCCCHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGSAAHKGKDQRPPRISKTARPEKSGQERMSGDSKAEGPTRAPVERRSRASNVWMAPGAR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
PVGKKRAEEASKDAEKKPRAGRPATGRAERRDGDRPTRPGKGRRER
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNRKDKSEKATAPRGKPAGKAAAGGAPRGKYGKAAKDEIREDGRTDGERIAKRLARAGL
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
ASRRDAEAMIEAGRVKVNGRVLSSPAFNVRPSDRIEVDDEPLPAAERTRLFLFHKPAGVV
CCCCHHHHHHHCCEEEECCEEECCCCCCCCCCCCEECCCCCCCCHHCCEEEEEECCCCEE
TTTRDPEGRRTIFDTLPEGLPRLITVGRLDINTEGLILLTNDGGLARALELPSTGWLRRY
EECCCCCCCHHHHHHHHHHHHHHEEECEEEECCCCEEEEECCCCCEEEEECCCCHHHEEE
RVRVHGKVDPKALAELEKGIAVDGVFYGAITASLDRQQGSNAWLTLGLREGKNREVKNVL
EEEECCCCCHHHHHHHHHCCEECHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
GALGLEVTRLIRVSYGPFQLGDLPEGAVLEVKGRTLRDQLGERLIEQAGADFEAPIAIPF
HHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECC
ANKPVRAERRKPEEEKRKTGLEENAGRQERKPANRRKSREEKHEEARDRLQTKRPDDFKG
CCCCCCHHHCCCHHHHHHCCCHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGSAAHKGKDQRPPRISKTARPEKSGQERMSGDSKAEGPTRAPVERRSRASNVWMAPGAR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
PVGKKRAEEASKDAEKKPRAGRPATGRAERRDGDRPTRPGKGRRER
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA