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The map label for this gene is dapD

Identifier: 110632748

GI number: 110632748

Start: 427694

End: 428548

Strand: Direct

Name: dapD

Synonym: Meso_0387

Alternate gene names: 110632748

Gene position: 427694-428548 (Clockwise)

Preceding gene: 110632743

Following gene: 110632749

Centisome position: 9.69

GC content: 61.87

Gene sequence:

>855_bases
ATGAAGACTTCCGACATCGCCGCGCTCGAACAGACGGTCGAAAAGGCTTTCGAAAACCGTGATTCAGTCAATACGGAAAC
GCGCGGCGAAATCCGCGAAGCCGTAGAGGCCGCGCTCGACCTGCTCGACAGCGGCGGCATGCGCGTCGCCCAACGCGGGG
AGGACGGTCAGTGGACTGTGAACCAGTGGCTAAAGAAGGCGGTTCTCCTCTCCTTCCGCTTGAATCCGATGCAGATCATC
AAGGGCGGCCCGGGCGATGCGGTCTGGTGGGACAAGGTCTCTTCGAAATTCGACGGCTGGAGCTCGAACGAGTTCGAAAA
AGCCGGGTTTCGCGCCGTGCCGAACTGCATCGTGCGCCGCTCGGCCTATATCGCGCCGGGCGCAGTGCTGATGCCTTCAT
TCGTCAATCTGGGAGCCTATGTGGGCCGCAACACCATGGTCGACACCTGGGCGACCGTCGGCTCCTGTGCGCAGATCGGT
GAGAACGTTCACCTTTCGGGCGGCGTGGGCATCGGCGGCGTTCTGGAGCCCATGCAGGCTGGACCGACCATCATCGAGGA
CAACTGCTTTATCGGCGCGCGCTCGGAAGTGGTGGAAGGCTGCATCGTGCGCGAGGGCTCGGTTCTCGGCATGGGCGTCT
TTATCGGCAAGTCCACCAAGATCGTCGACCGGGAGACCGGCCAGATCTTCTATGGCGAGGTGCCGCCCTATTCGGTGGTG
GTGGCGGGCACGATGCCCGGCAAGACCATGGCCAATGGCGAGCCTGGGCCAAACCTCTACTGCGCCGTGATCGTCAAGCG
CGTGGACGAGAAGACGCGGTCGAAAACCTCAATCAACGATCTCCTTAGGGATTGA

Upstream 100 bases:

>100_bases
TCGCATAGGTTCCGCGCCGGTGCCGGTCCGGCACATCCCAATGGTTGTTCTAGCCTATTGGGCAGCTCTTAACACCTCAT
GTAGCGGAGGCATTTCGCTG

Downstream 100 bases:

>100_bases
GGCCGAGGGTGGACCGCAACCAGCTCATTTGGCTGTTCTTCGGCTTCTCCGGCCGGTTGAGCCGAGCGCCCTATTTCCTG
GCGGGACTTCTGCTCGCCAT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKTSDIAALEQTVEKAFENRDSVNTETRGEIREAVEAALDLLDSGGMRVAQRGEDGQWTVNQWLKKAVLLSFRLNPMQII
KGGPGDAVWWDKVSSKFDGWSSNEFEKAGFRAVPNCIVRRSAYIAPGAVLMPSFVNLGAYVGRNTMVDTWATVGSCAQIG
ENVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGQIFYGEVPPYSVV
VAGTMPGKTMANGEPGPNLYCAVIVKRVDEKTRSKTSINDLLRD

Sequences:

>Translated_284_residues
MKTSDIAALEQTVEKAFENRDSVNTETRGEIREAVEAALDLLDSGGMRVAQRGEDGQWTVNQWLKKAVLLSFRLNPMQII
KGGPGDAVWWDKVSSKFDGWSSNEFEKAGFRAVPNCIVRRSAYIAPGAVLMPSFVNLGAYVGRNTMVDTWATVGSCAQIG
ENVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGQIFYGEVPPYSVV
VAGTMPGKTMANGEPGPNLYCAVIVKRVDEKTRSKTSINDLLRD
>Mature_284_residues
MKTSDIAALEQTVEKAFENRDSVNTETRGEIREAVEAALDLLDSGGMRVAQRGEDGQWTVNQWLKKAVLLSFRLNPMQII
KGGPGDAVWWDKVSSKFDGWSSNEFEKAGFRAVPNCIVRRSAYIAPGAVLMPSFVNLGAYVGRNTMVDTWATVGSCAQIG
ENVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGQIFYGEVPPYSVV
VAGTMPGKTMANGEPGPNLYCAVIVKRVDEKTRSKTSINDLLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=276, Percent_Identity=61.231884057971, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_MESSB (Q11LD4)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_672956.1
- ProteinModelPortal:   Q11LD4
- SMR:   Q11LD4
- STRING:   Q11LD4
- GeneID:   4182065
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0387
- NMPDR:   fig|266779.1.peg.4185
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q11LD4
- ProtClustDB:   PRK11830
- BioCyc:   MSP266779:MESO_0387-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30608; Mature: 30608

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 111-111 BINDING 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSDIAALEQTVEKAFENRDSVNTETRGEIREAVEAALDLLDSGGMRVAQRGEDGQWTV
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHH
NQWLKKAVLLSFRLNPMQIIKGGPGDAVWWDKVSSKFDGWSSNEFEKAGFRAVPNCIVRR
HHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHH
SAYIAPGAVLMPSFVNLGAYVGRNTMVDTWATVGSCAQIGENVHLSGGVGIGGVLEPMQA
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCHHHC
GPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGQIFYGEVPPYSVV
CCCEEECCCEECCHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCEEE
VAGTMPGKTMANGEPGPNLYCAVIVKRVDEKTRSKTSINDLLRD
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTSDIAALEQTVEKAFENRDSVNTETRGEIREAVEAALDLLDSGGMRVAQRGEDGQWTV
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHH
NQWLKKAVLLSFRLNPMQIIKGGPGDAVWWDKVSSKFDGWSSNEFEKAGFRAVPNCIVRR
HHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHH
SAYIAPGAVLMPSFVNLGAYVGRNTMVDTWATVGSCAQIGENVHLSGGVGIGGVLEPMQA
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCHHHC
GPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGQIFYGEVPPYSVV
CCCEEECCCEECCHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCEEE
VAGTMPGKTMANGEPGPNLYCAVIVKRVDEKTRSKTSINDLLRD
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA