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The map label for this gene is argB [H]

Identifier: 110632741

GI number: 110632741

Start: 422297

End: 423235

Strand: Direct

Name: argB [H]

Synonym: Meso_0380

Alternate gene names: 110632741

Gene position: 422297-423235 (Clockwise)

Preceding gene: 110632739

Following gene: 110632743

Centisome position: 9.57

GC content: 62.41

Gene sequence:

>939_bases
ATGCGATATGAGACGTGCGGTCCTATCGAAGCCCGGGCGAAGAGCATGACGGAAATCACCGAAACCGCTGAGGCGCAGGC
CGCCCTCCTTTCGGCGGCGCTGCCTTACATGCAGCGTTACGAGAACAAGACCGTGGTCATCAAATATGGTGGCCATGCAA
TGGGCGACATCGCGCTCGGCCGCGCCTTCGCCCGCGACGTGGCGCTGCTGAAGCAGTCCGGCGTGAATCCGATCGTCGTC
CATGGAGGCGGCCCGCAGATCGGCGACATGCTGAAGCGGATGGGCATCGAATCCAAATTCGAGGGCGGCCTGCGCGTCAC
CGACCAGAAAACGGTCGAGATCGTCGAAATGGTGCTGGCGGGCTCCATCAACAAGGAGATCGTGGCCCTCATCAACGCCG
AGGGCGAATGGGCGATCGGTCTCTGCGGCAAGGACGGCAACATGGTCTTCGCCGAGAAAGCGCGGAAAACCGTGGTGGAT
CCGGATTCCAATATCGAGCGCGTGCTCGATCTCGGGTTTGTCGGCGAGCCGGTGGAGGTGGACCGTACGCTGCTCGATCT
GCTCGCCCGCTCCGAAATGATCCCGGTGCTTGCGCCTGTCGCGCCAGGCCGCGACGGCTACACCTACAACATCAACGCCG
ACACATTTGCCGGCGCCATTGCCGGCGCGGTCAAGGCGAGCCGTCTGCTTTTCCTTACCGACGTGCCGGGCGTGCTCGAT
CGCGACAAGAAGCTGATCAATGAACTGACGGTTTCGCAGGCCCGCGCGCTCATCAAGGACGGAACCATCTCCGGCGGCAT
GATCCCGAAGGTGGAGACCTGCATCGAAGCCATTCAGCGGGGCGTTGAAGGCGTGGTCATCCTCAACGGCAAGACGGCCC
ATTCGGTGCTTTTGGAACTGTTCACGGAGCACGGGGCGGGAACGCTGATCGTCCCATGA

Upstream 100 bases:

>100_bases
TCTCCTCCGTCTCTCCTGAGAGTAGGGGAGGCGAAGCCAGGCGGCAAATCAAGGGCGCGTGAGCGGTCGGCGTCACTTCG
TCATTTGCGCTCGTGATTGA

Downstream 100 bases:

>100_bases
AGGTGAACCGGCGTTACGCCGCGGCGCGTGAGCCGGCCACCACTGTGTTACGGCCGCGCCGCTTGGCCTGATAGAGCCGC
TGGTCGGCCTCGCCCATGAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRYETCGPIEARAKSMTEITETAEAQAALLSAALPYMQRYENKTVVIKYGGHAMGDIALGRAFARDVALLKQSGVNPIVV
HGGGPQIGDMLKRMGIESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTVVD
PDSNIERVLDLGFVGEPVEVDRTLLDLLARSEMIPVLAPVAPGRDGYTYNINADTFAGAIAGAVKASRLLFLTDVPGVLD
RDKKLINELTVSQARALIKDGTISGGMIPKVETCIEAIQRGVEGVVILNGKTAHSVLLELFTEHGAGTLIVP

Sequences:

>Translated_312_residues
MRYETCGPIEARAKSMTEITETAEAQAALLSAALPYMQRYENKTVVIKYGGHAMGDIALGRAFARDVALLKQSGVNPIVV
HGGGPQIGDMLKRMGIESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTVVD
PDSNIERVLDLGFVGEPVEVDRTLLDLLARSEMIPVLAPVAPGRDGYTYNINADTFAGAIAGAVKASRLLFLTDVPGVLD
RDKKLINELTVSQARALIKDGTISGGMIPKVETCIEAIQRGVEGVVILNGKTAHSVLLELFTEHGAGTLIVP
>Mature_312_residues
MRYETCGPIEARAKSMTEITETAEAQAALLSAALPYMQRYENKTVVIKYGGHAMGDIALGRAFARDVALLKQSGVNPIVV
HGGGPQIGDMLKRMGIESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTVVD
PDSNIERVLDLGFVGEPVEVDRTLLDLLARSEMIPVLAPVAPGRDGYTYNINADTFAGAIAGAVKASRLLFLTDVPGVLD
RDKKLINELTVSQARALIKDGTISGGMIPKVETCIEAIQRGVEGVVILNGKTAHSVLLELFTEHGAGTLIVP

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=32.7659574468085, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789181, Length=299, Percent_Identity=25.4180602006689, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=277, Percent_Identity=26.3537906137184, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 33296; Mature: 33296

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYETCGPIEARAKSMTEITETAEAQAALLSAALPYMQRYENKTVVIKYGGHAMGDIALG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHH
RAFARDVALLKQSGVNPIVVHGGGPQIGDMLKRMGIESKFEGGLRVTDQKTVEIVEMVLA
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHH
GSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTVVDPDSNIERVLDLGFVGEPVEV
CCCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHH
DRTLLDLLARSEMIPVLAPVAPGRDGYTYNINADTFAGAIAGAVKASRLLFLTDVPGVLD
HHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCEEEEEECCCCHHH
RDKKLINELTVSQARALIKDGTISGGMIPKVETCIEAIQRGVEGVVILNGKTAHSVLLEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
FTEHGAGTLIVP
HHHCCCCEEECC
>Mature Secondary Structure
MRYETCGPIEARAKSMTEITETAEAQAALLSAALPYMQRYENKTVVIKYGGHAMGDIALG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHH
RAFARDVALLKQSGVNPIVVHGGGPQIGDMLKRMGIESKFEGGLRVTDQKTVEIVEMVLA
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHH
GSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTVVDPDSNIERVLDLGFVGEPVEV
CCCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHH
DRTLLDLLARSEMIPVLAPVAPGRDGYTYNINADTFAGAIAGAVKASRLLFLTDVPGVLD
HHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCEEEEEECCCCHHH
RDKKLINELTVSQARALIKDGTISGGMIPKVETCIEAIQRGVEGVVILNGKTAHSVLLEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
FTEHGAGTLIVP
HHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA