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The map label for this gene is murA

Identifier: 110632554

GI number: 110632554

Start: 234078

End: 235367

Strand: Reverse

Name: murA

Synonym: Meso_0192

Alternate gene names: 110632554

Gene position: 235367-234078 (Counterclockwise)

Preceding gene: 110632555

Following gene: 110632553

Centisome position: 5.33

GC content: 61.71

Gene sequence:

>1290_bases
ATGGACCGCATACGCATCCGCGGGGGCAGCGAGCTCAATGGAACGATCCCGATCTCCGGGGCGAAGAATGCCGCGCTGCC
GCTGATGATCGCTTCTCTTCTGACTGACGATACGCTGACATTGGAAAATGTCCCGCATCTTGCTGATGTAGAGCAACTGA
TCCGCATTCTCGGCAATCATGGCGTGGACTACTCCGTCAATGGCAGGCGCGAGAACCAGGACAAGGGCTATTCGCGCACC
GTCCATTTCACCGCTCGCAGCATCGTCGACACGACGGCTCCGTATGAACTCGTGTCCAAGATGCGGGCGAGCTTCTGGGT
TATTGGCCCGCTTCTGGCGCGGATGGGCGAGGCGAAAGTTTCGCTGCCGGGCGGTTGCGCCATTGGCACGCGCCCGGTGG
ATCTTTTCATCGAGGGCCTGCGCAGCCTGGGAGCTGCGATCGATATCGAAGGCGGCTACGTGATCGCGAGGGCGAAGGAC
GGCCTTGTTGGGACGCGGTTCCGTTTCCCGAAAGTGTCGGTCGGCGCCACCCATGTCCTGATGATGGCCGCGTCACTCGC
AAGGGGGCAGACGGTGCTGGAAAATGCCGCAAGAGAGCCGGAGATCGTCAATCTTGCCGACTGCCTCAACGCCATGGGCG
CTAAGATATCCGGTGCCGGCACTCCGACAATCACTATTGAAGGCGTCACCAGCCTTTCCGGCGCGCGCCATCGCATCATT
CCGGACCGGATCGAGACCGGCACCTATGCGTTGGCGGTCGCCATGGCGGGTGGCGACGTAATGCTTGAAGGGGCGCGGGC
CGATCTTCTTGAAACCGCGCTCGATGTCATTCAACAGACCGGGGCGGAAATCACCCGAGCCGATACCGGCATTAGGATCA
GGCGCAACGGCAACGGCATCAGCCCGGTCGACATCACGACCGAGCCGTTCCCCGGCTTTCCCACCGACCTGCAGGCTCAA
TTCATGGCCGTGATGACAAAGGCCAAGGGCAACTCACGGATCACAGAGACGATCTTCGAGAACCGCTTCATGCACGTGCA
GGAATTGGCGCGCCTCGGCGCGCGCATTTCACTATCCGGGCAAGAGGCCGTCGTGGAGGGGGTGGACCGGCTGAAAGGTG
CGCCCGTAATGGCGACCGACCTGCGGGCGTCGGTGTCTCTCCTGATCGCAGGCCTGGCAGCCGAGGGCGAAACCACCGTC
AATCGCGTATATCACCTCGATCGCGGTTTTGAGCGGCTGGAGGAAAAACTGTCCAGCTGCGGCGCTGACATTGAGCGCAT
TTCCGGCTGA

Upstream 100 bases:

>100_bases
CGGACGCATTTTCTTGAACCGGCCGCGGGGTTGCTCTAGGAGAGGCAAGATCAGCAACCGTCAACACCGGGATTCCCTCT
CTCCCGGGAAAGAGACATTC

Downstream 100 bases:

>100_bases
CCGCCGCAGCAGGAGCTACCAACCGGTCCGCCGGCCCGGAATATGAGTGGAGTGATGGAACTGTTGAAGCTCGCCGCACT
CGATGAGGAAGATCTGAACA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDRIRIRGGSELNGTIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRRENQDKGYSRT
VHFTARSIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFIEGLRSLGAAIDIEGGYVIARAKD
GLVGTRFRFPKVSVGATHVLMMAASLARGQTVLENAAREPEIVNLADCLNAMGAKISGAGTPTITIEGVTSLSGARHRII
PDRIETGTYALAVAMAGGDVMLEGARADLLETALDVIQQTGAEITRADTGIRIRRNGNGISPVDITTEPFPGFPTDLQAQ
FMAVMTKAKGNSRITETIFENRFMHVQELARLGARISLSGQEAVVEGVDRLKGAPVMATDLRASVSLLIAGLAAEGETTV
NRVYHLDRGFERLEEKLSSCGADIERISG

Sequences:

>Translated_429_residues
MDRIRIRGGSELNGTIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRRENQDKGYSRT
VHFTARSIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFIEGLRSLGAAIDIEGGYVIARAKD
GLVGTRFRFPKVSVGATHVLMMAASLARGQTVLENAAREPEIVNLADCLNAMGAKISGAGTPTITIEGVTSLSGARHRII
PDRIETGTYALAVAMAGGDVMLEGARADLLETALDVIQQTGAEITRADTGIRIRRNGNGISPVDITTEPFPGFPTDLQAQ
FMAVMTKAKGNSRITETIFENRFMHVQELARLGARISLSGQEAVVEGVDRLKGAPVMATDLRASVSLLIAGLAAEGETTV
NRVYHLDRGFERLEEKLSSCGADIERISG
>Mature_429_residues
MDRIRIRGGSELNGTIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRRENQDKGYSRT
VHFTARSIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFIEGLRSLGAAIDIEGGYVIARAKD
GLVGTRFRFPKVSVGATHVLMMAASLARGQTVLENAAREPEIVNLADCLNAMGAKISGAGTPTITIEGVTSLSGARHRII
PDRIETGTYALAVAMAGGDVMLEGARADLLETALDVIQQTGAEITRADTGIRIRRNGNGISPVDITTEPFPGFPTDLQAQ
FMAVMTKAKGNSRITETIFENRFMHVQELARLGARISLSGQEAVVEGVDRLKGAPVMATDLRASVSLLIAGLAAEGETTV
NRVYHLDRGFERLEEKLSSCGADIERISG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=48.951048951049, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_MESSB (Q11LX8)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_672762.1
- ProteinModelPortal:   Q11LX8
- SMR:   Q11LX8
- STRING:   Q11LX8
- GeneID:   4179753
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0192
- NMPDR:   fig|266779.1.peg.3350
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q11LX8
- ProtClustDB:   PRK09369
- BioCyc:   MSP266779:MESO_0192-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45756; Mature: 45756

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIRGGSELNGTIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GVDYSVNGRRENQDKGYSRTVHFTARSIVDTTAPYELVSKMRASFWVIGPLLARMGEAKV
CCCEEECCCCCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLFIEGLRSLGAAIDIEGGYVIARAKDGLVGTRFRFPKVSVGATHVL
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEEEECCCCEECEEECCCCCCCHHHHH
MMAASLARGQTVLENAAREPEIVNLADCLNAMGAKISGAGTPTITIEGVTSLSGARHRII
HHHHHHHCCHHHHHHCCCCCCEEEHHHHHHHHCCEECCCCCCEEEEECCCCCCCCCCCCC
PDRIETGTYALAVAMAGGDVMLEGARADLLETALDVIQQTGAEITRADTGIRIRRNGNGI
CCHHCCCCEEEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCC
SPVDITTEPFPGFPTDLQAQFMAVMTKAKGNSRITETIFENRFMHVQELARLGARISLSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
QEAVVEGVDRLKGAPVMATDLRASVSLLIAGLAAEGETTVNRVYHLDRGFERLEEKLSSC
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GADIERISG
CCCHHHCCC
>Mature Secondary Structure
MDRIRIRGGSELNGTIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GVDYSVNGRRENQDKGYSRTVHFTARSIVDTTAPYELVSKMRASFWVIGPLLARMGEAKV
CCCEEECCCCCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLFIEGLRSLGAAIDIEGGYVIARAKDGLVGTRFRFPKVSVGATHVL
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEEEECCCCEECEEECCCCCCCHHHHH
MMAASLARGQTVLENAAREPEIVNLADCLNAMGAKISGAGTPTITIEGVTSLSGARHRII
HHHHHHHCCHHHHHHCCCCCCEEEHHHHHHHHCCEECCCCCCEEEEECCCCCCCCCCCCC
PDRIETGTYALAVAMAGGDVMLEGARADLLETALDVIQQTGAEITRADTGIRIRRNGNGI
CCHHCCCCEEEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCC
SPVDITTEPFPGFPTDLQAQFMAVMTKAKGNSRITETIFENRFMHVQELARLGARISLSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
QEAVVEGVDRLKGAPVMATDLRASVSLLIAGLAAEGETTVNRVYHLDRGFERLEEKLSSC
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GADIERISG
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA