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The map label for this gene is lcrD [H]

Identifier: 110632481

GI number: 110632481

Start: 145515

End: 147590

Strand: Direct

Name: lcrD [H]

Synonym: Meso_0119

Alternate gene names: 110632481

Gene position: 145515-147590 (Clockwise)

Preceding gene: 110632480

Following gene: 110632482

Centisome position: 3.3

GC content: 57.37

Gene sequence:

>2076_bases
ATGAATCTCATAAAGCCCTTGGCCGCAATAGCGCGGCAGAAGGACGTCTTTCTCGTCCTCGTATTCGCGCTCGTCCTATT
GATGGTCATTCTGCCGTTGCCGCCCGCAGCGATGGACCTGATGATCACGCTGAATGTCAGTGCGTCCATCATCATTCTCT
TGATGTCGCTGCAGATGCACAATCCGGTTCAGTTCTCCACCTTTCCGGCGCTGCTTCTGGTGACGACGCTGTTTCGGCTT
TCGATTTCCATCTCCACCACAAGGCTTATTCTGCTTGAGGGGGATGCTGGCCGCATTGTTGAGACCTTCGGCCAGGTGGC
GATGGGGGGCAATCTGGCCGTCGGGCTGGTGACGTTCCTCATCATCACGGTGGTGCAGTTTCTGGTCATCACAAAAGGCG
CCGATCGCGTCGCCGAAGTGGGCGCGCGTTTCACGCTGGACGGCATGCCGGGCAAGCAGATGAGCATCGATGCGGATGTC
CGGGCCGGCAATATGGACCAGCTCGATGCAAGGCATGCGCGACAGAACCTGGAGCGCGAAGCCAAGCTTTTCGGCGCCAT
GGACGGAGCAATGAAATTCGTCAAGGGAGATGCGATAGCCGGCCTTGTCATCACTGTCATAAACCTTGTGGGAGGCGTGG
CCATAGGCATGGCCCAGCGGGGGGTGGGTTTCGGCGAGGCTTTGAGCCTCTACGCGCTCCTGACGGTCGGCGACGGGTTG
GTGGCGCAAATCCCCGCGCTTCTGATCTCCGTTGCCGCGGGCAATATGGTTACGCGCGTAACCAACCCCAACGGCATGGA
TCTGGGCGCGGAGATCGCTCAGCAGTTCGTCGCCAACCGCCGCACGATCGTCATGGCCGGCATCATCATCGCCCTGTTTG
GTTTGGTCCCCGGCTTTCCAACATGGATTTTCGTTTCTGTTGGTTCAGCAATGACGGGGGGGGTAATTTGGACGATACGC
CGGCAACACCGGGACGTGCTGAGCGCGCAGACGGATTGGTCCCTTCGCCTGGATCTGCTTCAACGGCAGTGTGCCGAAAT
TGCCATGCGAACCGGAGCGAAAGAAGCGGTAAGGCTCATTCTTCCAAAGGAGATATATAAGCTGGATGTCACTGCGTTCT
TTTCCGCTTTCGAAGCCGTCAGGATAAGCATCGCACAGGAATATGGAATACCGACCGGCTATTGGCTGTTTGAAGTGGAC
GAGGGATCGCCGCACTCATACCAGATATATGTAAACCAGGAGCTCGCCGATTGCGGAATCTTCAGGGCCGATAGCCTGTT
CGTAAAGGCGCATACTTCCTATCTCGATGCCCTCGGAATCCCGTGGCTAAGCGGCTTTGGCCGCAGGGAGGGGGCGCTTG
TCCCCACCGATCAGGAGCAAAGGCTAGCTGAAGAGAACATCGTCTATTGGCGCCCGATGGAGCAACTGCTGATGCACCTG
AAGCGGGTAGCAGTTGAACGGCTCGACGTTATGGCCAGCCTGCAGAACATAACAGCCATCCTGAATGAAGTGCAAACGAA
CAATCCGGCGCTCGTTGGCGATCTGCGGGAAGCGGCATCGAACAATCAAATCGCCGGCGTTATACGGAACCTGTTGCGCG
AGCGCATCCCCGTCACCAGCCGGGTGCGCATTCTCGAGGGTATTCTGAAATGGTCGCAGAAGCGGCCGGACCCCGGCTAT
CTGGCCCAGAAGGTGCGTATCGAAATCGCTGATTTCATTACGAAGCGGTTTGCCGCCGATGGCTTCCTGCCGGTGGTGGT
GGTTTCGCCGACTGTTGAATCTCTCATGCGCGAGGGAATGCGAAACACCGAGGAGGGCAATTTTCTCATTCTGGAGCCTT
CAATCTCAGCCTATATCGCCAAACAGGCCAAACAGATCTGTGGGGAAGAATTCCGGCGCGGTCACGATCCGGTCCTGATC
ATGCAGCAGGATGTCCGCCTGGCGATGCATAACATCCTTTATGAGCACGGCATACACCTGCCGGTACTGGCTTATCAGGA
GATCACGCCTGAAACGGTGATTTATCCGGTCGGCTTCCTGTTGGCCGAACCTGGCGAAGACGCAGGGGAACTGTAG

Upstream 100 bases:

>100_bases
TTGAGACGCCGGTTCTGCATTCCAAGGCCGATATGCCCGCCGAAGGCCAGTTCAGCCCGGGGTTGTCGAAAATACCCTGA
CAGACCCCATTAGGAAACGA

Downstream 100 bases:

>100_bases
GCCTGTCACTCAGTGCCAGTCAGCATATCAGAAAATTTGAAGAGGATATTTACTAAATCGGAAGTATATCTTGAAAGTTG
ATGAAATCGAAAGTTTAATA

Product: type III secretion FHIPEP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MNLIKPLAAIARQKDVFLVLVFALVLLMVILPLPPAAMDLMITLNVSASIIILLMSLQMHNPVQFSTFPALLLVTTLFRL
SISISTTRLILLEGDAGRIVETFGQVAMGGNLAVGLVTFLIITVVQFLVITKGADRVAEVGARFTLDGMPGKQMSIDADV
RAGNMDQLDARHARQNLEREAKLFGAMDGAMKFVKGDAIAGLVITVINLVGGVAIGMAQRGVGFGEALSLYALLTVGDGL
VAQIPALLISVAAGNMVTRVTNPNGMDLGAEIAQQFVANRRTIVMAGIIIALFGLVPGFPTWIFVSVGSAMTGGVIWTIR
RQHRDVLSAQTDWSLRLDLLQRQCAEIAMRTGAKEAVRLILPKEIYKLDVTAFFSAFEAVRISIAQEYGIPTGYWLFEVD
EGSPHSYQIYVNQELADCGIFRADSLFVKAHTSYLDALGIPWLSGFGRREGALVPTDQEQRLAEENIVYWRPMEQLLMHL
KRVAVERLDVMASLQNITAILNEVQTNNPALVGDLREAASNNQIAGVIRNLLRERIPVTSRVRILEGILKWSQKRPDPGY
LAQKVRIEIADFITKRFAADGFLPVVVVSPTVESLMREGMRNTEEGNFLILEPSISAYIAKQAKQICGEEFRRGHDPVLI
MQQDVRLAMHNILYEHGIHLPVLAYQEITPETVIYPVGFLLAEPGEDAGEL

Sequences:

>Translated_691_residues
MNLIKPLAAIARQKDVFLVLVFALVLLMVILPLPPAAMDLMITLNVSASIIILLMSLQMHNPVQFSTFPALLLVTTLFRL
SISISTTRLILLEGDAGRIVETFGQVAMGGNLAVGLVTFLIITVVQFLVITKGADRVAEVGARFTLDGMPGKQMSIDADV
RAGNMDQLDARHARQNLEREAKLFGAMDGAMKFVKGDAIAGLVITVINLVGGVAIGMAQRGVGFGEALSLYALLTVGDGL
VAQIPALLISVAAGNMVTRVTNPNGMDLGAEIAQQFVANRRTIVMAGIIIALFGLVPGFPTWIFVSVGSAMTGGVIWTIR
RQHRDVLSAQTDWSLRLDLLQRQCAEIAMRTGAKEAVRLILPKEIYKLDVTAFFSAFEAVRISIAQEYGIPTGYWLFEVD
EGSPHSYQIYVNQELADCGIFRADSLFVKAHTSYLDALGIPWLSGFGRREGALVPTDQEQRLAEENIVYWRPMEQLLMHL
KRVAVERLDVMASLQNITAILNEVQTNNPALVGDLREAASNNQIAGVIRNLLRERIPVTSRVRILEGILKWSQKRPDPGY
LAQKVRIEIADFITKRFAADGFLPVVVVSPTVESLMREGMRNTEEGNFLILEPSISAYIAKQAKQICGEEFRRGHDPVLI
MQQDVRLAMHNILYEHGIHLPVLAYQEITPETVIYPVGFLLAEPGEDAGEL
>Mature_691_residues
MNLIKPLAAIARQKDVFLVLVFALVLLMVILPLPPAAMDLMITLNVSASIIILLMSLQMHNPVQFSTFPALLLVTTLFRL
SISISTTRLILLEGDAGRIVETFGQVAMGGNLAVGLVTFLIITVVQFLVITKGADRVAEVGARFTLDGMPGKQMSIDADV
RAGNMDQLDARHARQNLEREAKLFGAMDGAMKFVKGDAIAGLVITVINLVGGVAIGMAQRGVGFGEALSLYALLTVGDGL
VAQIPALLISVAAGNMVTRVTNPNGMDLGAEIAQQFVANRRTIVMAGIIIALFGLVPGFPTWIFVSVGSAMTGGVIWTIR
RQHRDVLSAQTDWSLRLDLLQRQCAEIAMRTGAKEAVRLILPKEIYKLDVTAFFSAFEAVRISIAQEYGIPTGYWLFEVD
EGSPHSYQIYVNQELADCGIFRADSLFVKAHTSYLDALGIPWLSGFGRREGALVPTDQEQRLAEENIVYWRPMEQLLMHL
KRVAVERLDVMASLQNITAILNEVQTNNPALVGDLREAASNNQIAGVIRNLLRERIPVTSRVRILEGILKWSQKRPDPGY
LAQKVRIEIADFITKRFAADGFLPVVVVSPTVESLMREGMRNTEEGNFLILEPSISAYIAKQAKQICGEEFRRGHDPVLI
MQQDVRLAMHNILYEHGIHLPVLAYQEITPETVIYPVGFLLAEPGEDAGEL

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=673, Percent_Identity=31.7979197622585, Blast_Score=296, Evalue=4e-81,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75844; Mature: 75844

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIKPLAAIARQKDVFLVLVFALVLLMVILPLPPAAMDLMITLNVSASIIILLMSLQMH
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCC
NPVQFSTFPALLLVTTLFRLSISISTTRLILLEGDAGRIVETFGQVAMGGNLAVGLVTFL
CCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
IITVVQFLVITKGADRVAEVGARFTLDGMPGKQMSIDADVRAGNMDQLDARHARQNLERE
HHHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHH
AKLFGAMDGAMKFVKGDAIAGLVITVINLVGGVAIGMAQRGVGFGEALSLYALLTVGDGL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
VAQIPALLISVAAGNMVTRVTNPNGMDLGAEIAQQFVANRRTIVMAGIIIALFGLVPGFP
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
TWIFVSVGSAMTGGVIWTIRRQHRDVLSAQTDWSLRLDLLQRQCAEIAMRTGAKEAVRLI
CEEEEECCCHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LPKEIYKLDVTAFFSAFEAVRISIAQEYGIPTGYWLFEVDEGSPHSYQIYVNQELADCGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCHHHCCC
FRADSLFVKAHTSYLDALGIPWLSGFGRREGALVPTDQEQRLAEENIVYWRPMEQLLMHL
EECCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHH
KRVAVERLDVMASLQNITAILNEVQTNNPALVGDLREAASNNQIAGVIRNLLRERIPVTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHCCHHH
RVRILEGILKWSQKRPDPGYLAQKVRIEIADFITKRFAADGFLPVVVVSPTVESLMREGM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCC
RNTEEGNFLILEPSISAYIAKQAKQICGEEFRRGHDPVLIMQQDVRLAMHNILYEHGIHL
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCC
PVLAYQEITPETVIYPVGFLLAEPGEDAGEL
CEEEHHHCCCCCEEEECHHEEECCCCCCCCC
>Mature Secondary Structure
MNLIKPLAAIARQKDVFLVLVFALVLLMVILPLPPAAMDLMITLNVSASIIILLMSLQMH
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCC
NPVQFSTFPALLLVTTLFRLSISISTTRLILLEGDAGRIVETFGQVAMGGNLAVGLVTFL
CCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
IITVVQFLVITKGADRVAEVGARFTLDGMPGKQMSIDADVRAGNMDQLDARHARQNLERE
HHHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHH
AKLFGAMDGAMKFVKGDAIAGLVITVINLVGGVAIGMAQRGVGFGEALSLYALLTVGDGL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
VAQIPALLISVAAGNMVTRVTNPNGMDLGAEIAQQFVANRRTIVMAGIIIALFGLVPGFP
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
TWIFVSVGSAMTGGVIWTIRRQHRDVLSAQTDWSLRLDLLQRQCAEIAMRTGAKEAVRLI
CEEEEECCCHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LPKEIYKLDVTAFFSAFEAVRISIAQEYGIPTGYWLFEVDEGSPHSYQIYVNQELADCGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCHHHCCC
FRADSLFVKAHTSYLDALGIPWLSGFGRREGALVPTDQEQRLAEENIVYWRPMEQLLMHL
EECCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHH
KRVAVERLDVMASLQNITAILNEVQTNNPALVGDLREAASNNQIAGVIRNLLRERIPVTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHCCHHH
RVRILEGILKWSQKRPDPGYLAQKVRIEIADFITKRFAADGFLPVVVVSPTVESLMREGM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCC
RNTEEGNFLILEPSISAYIAKQAKQICGEEFRRGHDPVLIMQQDVRLAMHNILYEHGIHL
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCC
PVLAYQEITPETVIYPVGFLLAEPGEDAGEL
CEEEHHHCCCCCEEEECHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]