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The map label for this gene is yheS [H]

Identifier: 109947742

GI number: 109947742

Start: 1051954

End: 1053555

Strand: Reverse

Name: yheS [H]

Synonym: Hac_1217

Alternate gene names: 109947742

Gene position: 1053555-1051954 (Counterclockwise)

Preceding gene: 109947745

Following gene: 109947741

Centisome position: 67.8

GC content: 39.64

Gene sequence:

>1602_bases
ATGCTGCAAACCATCAACTTAACGCAACGCTATGCGACTAAAAAATTGTTTGAAAATGTGAATATCAAGTTGGATAAAAA
CAAGCGTTACGGGCTTATTGGGGCTAATGGGGCAGGGAAATCCACTTTTTTAAAGATTTTAAGCAAGAGCATTGATTGTA
GCAGTGGGGAAGTCATCATCACAAGTGGCATGAGAATGGGGGTTTTAGGGCAGGATCAATACGCTTTTGAAGACTTGAGC
CTTAAAGATGCGGTTTTAATAGGCAATAAGCGTTTGTATGACGCCATCAAAGAAAAAGAGCGTTTATACACAGAGAGTGA
TTTGAGCGATGATAAAGTGAATGCCAAATTAGGGGAGTTAGAAACCATTTGCGTAGAAGAAGATCCCATGTATGAATGCG
AAGTGGTGATTGAAAAAATTTTAGAAGATTTAGGTATTCCTAGCTCTAGGCATAATGATTTGATGAAAACCCTGCCAAGC
AGCGATAAATTTAAAATCCTTTTAGCTCAAGTGTTATTCCCTAAACCGGATATTTTGCTTTTAGATGAGCCTACAAACAA
TTTGGATTTAAACGCCATTGAATGGCTAGAAAACAACCTCAAACGCCATGAAGGCACGATGGTCGTCATTAGCCATGACA
GGCATTTTTTGAATGCGGTATGCACGCATATTTTAGATTTGGATTTTCACAGCGTGCGCGAATTTAGTGGGAATTATGAC
GATTGGTATATCGCCTCTACTCTGATCGCTAAACAGCAAGAGGCTGAACGCAATAAAAAACTCAAAGAAAAAGAAGAGCT
AGAAAAATTTATCGCTCGTTTTAGCGCTAACGCCTCTAAAGCCAAGCAAGCGACTAGCCGTCAAAAACAATTGGATAAAT
TAGACATTCAAAGCCTAGCGGTATCCAGCCGAAGAGATCCTAGCATTATTTTTAAACCCAAACGCACCATTGGTAACGAA
GCTTTAGAATGCGAAAATATCTCTAAAAGTTATGATGGGCAAGTTATTTTAAATCAAGTGAGCTTGAAAGTGATGCCTAA
AGATAAAATTGCTCTCATAGGGCCAAATGGCGTGGGTAAATCCACGCTTTGTAAAATTTTAGTAGAAGAGTTAAAGCCTG
ATAAGGGCGTGGTGAAATGGGGGGCTACCGTTTCAAAAGGCTATTTCCCCCAAAATGTGAGCGAAGAAATTAGCGGCGAA
GAGACCTTGTATCAATGGCTCTTTAATTTTAATAAAAAGATTGAAAGCGCTGAGGTGAGAAACGCTTTAGGGAGAATGCT
TTTTAATGGCGAAGAGCAAGAAAAGTGCGTGAACGCTTTAAGTGGGGGCGAAAAACACCGAATGGTTTTATCCAAGCTCA
TGCTAGAAGGGGGGAATTTCTTAGTCTTAGATGAGCCGACTAACCATTTGGATTTAGAAGCGATTATTGCTTTAGGCGAA
GCGCTTTTTAAATTTGATGGGGCAGTGATTTGTATAAGCCATGACAGAGAACTGATTGATGCGTATGCAAACCGGATCAT
TGAATTAGTCCCAAGCCCTAAAGGCGCTCAAATCATTGATTTTAAAGGCAACTATGAAGAATATTTAGCGAGCAAGAAAT
AA

Upstream 100 bases:

>100_bases
ATTGAAAGAATAAACTGACTAATTTTATACAAAAAAAAAACAATACAAGCTATGCTACAATAAACTTTCTATAAAATCCA
AGGGAATAAGGAATCATAAG

Downstream 100 bases:

>100_bases
AATGAAGCCACGAGACATTGAAATCATTCAAAGCGTTTTAGAGATTACAGGGCCTATTAGCCCTACTGAAGTTTATAATA
AAGCCAAAGAGCTTTTTGAA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTESDLSDDKVNAKLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQVILNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGAQIIDFKGNYEEYLASKK

Sequences:

>Translated_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTESDLSDDKVNAKLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQVILNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGAQIIDFKGNYEEYLASKK
>Mature_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYTESDLSDDKVNAKLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQVILNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGAQIIDFKGNYEEYLASKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=541, Percent_Identity=32.3475046210721, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI27881506, Length=541, Percent_Identity=32.3475046210721, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI148612853, Length=539, Percent_Identity=30.4267161410019, Blast_Score=233, Evalue=5e-61,
Organism=Homo sapiens, GI69354671, Length=535, Percent_Identity=30.4672897196262, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI10947135, Length=535, Percent_Identity=30.4672897196262, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1787041, Length=533, Percent_Identity=43.1519699812383, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1789751, Length=530, Percent_Identity=31.8867924528302, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367384, Length=537, Percent_Identity=32.5884543761639, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787182, Length=548, Percent_Identity=30.1094890510949, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=32.1243523316062, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788897, Length=543, Percent_Identity=21.1786372007366, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=23.8738738738739, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=526, Percent_Identity=31.9391634980989, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17555318, Length=508, Percent_Identity=30.1181102362205, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17559834, Length=509, Percent_Identity=30.4518664047151, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320874, Length=505, Percent_Identity=33.6633663366337, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=516, Percent_Identity=31.2015503875969, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6325030, Length=411, Percent_Identity=26.0340632603406, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=420, Percent_Identity=25.4761904761905, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323278, Length=416, Percent_Identity=23.5576923076923, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666836, Length=501, Percent_Identity=32.9341317365269, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=29.608938547486, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=29.608938547486, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=29.3893129770992, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60029; Mature: 60029

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMRMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYTESDLSDDKVNAKLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCHHCCHHCCE
ETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDGQVILNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGAQIIDFKGNYEEYLASKK
HHHHCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCEEEEECCCHHHHHCCCC
>Mature Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMRMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYTESDLSDDKVNAKLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCHHCCHHCCE
ETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLIAKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDGQVILNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDKGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGAQIIDFKGNYEEYLASKK
HHHHCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCEEEEECCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]