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The map label for this gene is nixA [H]

Identifier: 109947719

GI number: 109947719

Start: 1030711

End: 1031688

Strand: Reverse

Name: nixA [H]

Synonym: Hac_1190

Alternate gene names: 109947719

Gene position: 1031688-1030711 (Counterclockwise)

Preceding gene: 109947722

Following gene: 109947717

Centisome position: 66.39

GC content: 41.41

Gene sequence:

>978_bases
TTGGCGATTGTGTTTTTACACATCTTGGGTTTAGTTTTGCTCTTTATGGCCAACAACGCCTCTTTTTATGCAGCGGCTTC
TATGGCTTACATGCTAGGGGCAAAGCATGCGTTTGATGCGGATCATATCGCTTGTATAGACAACACGATTAGAAAGCTCA
CCCAACAAGGTAAAAACGCCTATGGTGTGGGGTTTTACTTTTCTATGGGGCATTCAAGCGTGGTGATTTTAATGACCATT
GTCAGCGCGTTTGCGATCGCTTGGGCTAAAGAGCATACGCCGATGCTAGAAGAAGTAGGGGGAGTAGTGGGGACTTTGGT
TTCCGGGCTTTTTTTACTCATCATAGGGCTATTAAATGCAATTATTTTGGTGGATTTGTTAAAGATTTTCAAGCAATCGC
ATTCTAATGAACGCTTGAGCCAGCAACAAAACGAAGAGATCGAACGGCTTTTAACGAGTAGGGGCTTACTCAATCGCTTT
TTTAAACCCTTGTTTAATTTCGTTTCTAAATCGTGGCATATTTATCCTGTGGGTTTTCTTTTTGGACTCGGTTTTGATAC
CGCTAGTGAAATCGCGCTTTTGGCCCTTTCTAGCAGTGCGATTAAAGTGAGTGTGGTGGGCATGCTCTCTTTACCCATTC
TTTTTGCCGCTGGCATGAGTTTGTTTGACACGCTAGATGGGGCGTTCATGCTTAAAGCGTATGATTGGGCGTTCAAAACC
CCTTTAAGAAAAATCTATTACAATATCTCTATCACCGCCTTGAGCGTGTTTATCGCTCTTTTTATTGGGTTGATTGAGCT
TTTTCAAGTCGTTAGCGAGAAGCTCCATTTAAAATTTGAAAACCGCCTTTTAAGCACCCTACAAAGTCTAGAATTTACAG
ACTTAGGCTATTACTTGGTGGGCTTATTTGTGGTAGCGTTTTTAGGCTCGTTCTTTTTATGGAAAATCAAATTTTCTAAA
TTAGAGAGCTCGATTTAA

Upstream 100 bases:

>100_bases
AAAATGTTTAACACCGCTCGCTTTCTTTAGGCTTTTTATATTACAATTACTCAAAAAATCTTATTAAAGGCACGCTGTGA
AATTGTGGTTTCCTTATTTT

Downstream 100 bases:

>100_bases
GCTCTCAAATTATCATTCAACAAATCTTTAAGGCTTTTGTTTGAAAAACTTTGTTTTGGCATAAAGACTTTAGGGTTTGA
AAGGCTTTCACTCAAATAAG

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAIVFLHILGLVLLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSVVILMTI
VSAFAIAWAKEHTPMLEEVGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKQSHSNERLSQQQNEEIERLLTSRGLLNRF
FKPLFNFVSKSWHIYPVGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAYDWAFKT
PLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLSTLQSLEFTDLGYYLVGLFVVAFLGSFFLWKIKFSK
LESSI

Sequences:

>Translated_325_residues
MAIVFLHILGLVLLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSVVILMTI
VSAFAIAWAKEHTPMLEEVGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKQSHSNERLSQQQNEEIERLLTSRGLLNRF
FKPLFNFVSKSWHIYPVGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAYDWAFKT
PLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLSTLQSLEFTDLGYYLVGLFVVAFLGSFFLWKIKFSK
LESSI
>Mature_324_residues
AIVFLHILGLVLLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSVVILMTIV
SAFAIAWAKEHTPMLEEVGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKQSHSNERLSQQQNEEIERLLTSRGLLNRFF
KPLFNFVSKSWHIYPVGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAYDWAFKTP
LRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLSTLQSLEFTDLGYYLVGLFVVAFLGSFFLWKIKFSKL
ESSI

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36137; Mature: 36006

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVFLHILGLVLLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNA
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
YGVGFYFSMGHSSVVILMTIVSAFAIAWAKEHTPMLEEVGGVVGTLVSGLFLLIIGLLNA
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IILVDLLKIFKQSHSNERLSQQQNEEIERLLTSRGLLNRFFKPLFNFVSKSWHIYPVGFL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
FGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAYDWAFKT
HHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLSTLQSLEFTDLGYYLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GLFVVAFLGSFFLWKIKFSKLESSI
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIVFLHILGLVLLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC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HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]