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The map label for this gene is gpsA

Identifier: 109947572

GI number: 109947572

Start: 899833

End: 900771

Strand: Reverse

Name: gpsA

Synonym: Hac_1037

Alternate gene names: 109947572

Gene position: 900771-899833 (Counterclockwise)

Preceding gene: 109947573

Following gene: 109947571

Centisome position: 57.97

GC content: 43.02

Gene sequence:

>939_bases
ATGGAAATTTCAGTGTTTGGTGGCGGAGCGTGGGGGAGGGCTTTAGCCTTTGCTTTTGGAGAAAAGAATGAAGTTAAAAT
CATTTCAAGGCGGGATTTAAACGAGCCGTTAAAAAAGCTCAATGACGCCTTGATCTCTAAAGGCTCTGCTCCTATAGAGC
AAGTAGATTTAGAAACAGGCTTAAAAGCATCCCTATATGTCGTAGCCATTAGCGTGCAGCATTTAAGAGAATGGTTTCAA
AACGCTTCTTTACCCAAAAACGCTAAAGTTTTAATCGCCTCTAAAGGGATAGAAGTTTTAAACAAGGCGTTTGTGAGCGA
GATCGCAAAGGATTTTATTGAGCCTAACCATTTGTGTTTTTTAGCCGGTCCGAGTTTTGCGGCTGAAATCATTCAAGGCC
TGCCTTGCGCGCTAGTCATCCATTCTAATAACCAGGCTTTAGCGCTAGAATTTGCCAATAAAACCCCCTCTTTTATCAGA
GCTTACGCCCAACAAGATATTATAGGAGGTGAAATCGCTGGAGCGTATAAAAATGTGATAGCCATTGCTGGGGGGGTTTG
TGATGGCTTGAAACTAGGCAATAGCGCTAAAGCGAGTTTGTTGTCTCGTGGTTTAGTGGAAATGCAACGCTTTGGGGCGT
TCTTTGGGGGGAAAACAGAGACTTTTTTAGGTTTGTCTGGGGCTGGGGATTTGTTTTTAACCGCTAATTCTATTTTATCT
AGGAATTATCGTGTGGGTTTGGGACTAGCCCAAAACAAGCCTTTAGAGGTGGTGTTAGAAGAATTAGGCGAAGTGGCTGA
AGGGGTGAAAACGACGAACGCCATTGTAGAAATCGCTAAAAAATACGGCATTTATACGCCCATTGCGAGCGAATTAGCCT
TGCTTTTAAAGGGTAAAAGTGTGCTAGAGAGCATGAACGATTTGATTAGACGCGCTTAA

Upstream 100 bases:

>100_bases
ATTTAAAAATTAAAAAATTTTTTAAACCACCCTTTTTAATCAAAAATAGACTTATTATTGTAAAATGACAAGTTATACAA
TCAATTAAATTAGGAATTTA

Downstream 100 bases:

>100_bases
AGGAGAGAGCATGCAAGATTTTTCAAGTTTATTATTAAAATTACAAGAATATTGGAAGAATCAAGGGTGTTTGGTGATCC
AGCCTTATGATATCCCTGCA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETGLKASLYVVAISVQHLREWFQ
NASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIR
AYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILS
RNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKSVLESMNDLIRRA

Sequences:

>Translated_312_residues
MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETGLKASLYVVAISVQHLREWFQ
NASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIR
AYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILS
RNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKSVLESMNDLIRRA
>Mature_312_residues
MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETGLKASLYVVAISVQHLREWFQ
NASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIR
AYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILS
RNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKSVLESMNDLIRRA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=324, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33695088, Length=172, Percent_Identity=31.9767441860465, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=31.2883435582822, Blast_Score=157, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_HELAH (Q17X25)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664800.1
- ProteinModelPortal:   Q17X25
- SMR:   Q17X25
- STRING:   Q17X25
- GeneID:   4177269
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1037
- NMPDR:   fig|382638.8.peg.1006
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- BioCyc:   HACI382638:HAC_1037-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33362; Mature: 33362

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 177-177 BINDING 95-95 BINDING 95-95 BINDING 127-127 BINDING 241-241 BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETG
CEEEEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCC
LKASLYVVAISVQHLREWFQNASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCF
CCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEE
LAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIRAYAQQDIIGGEIAGAYKNVI
EECCHHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHH
AIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHC
RNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKS
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
VLESMNDLIRRA
HHHHHHHHHHCC
>Mature Secondary Structure
MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETG
CEEEEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCC
LKASLYVVAISVQHLREWFQNASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCF
CCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEE
LAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIRAYAQQDIIGGEIAGAYKNVI
EECCHHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHH
AIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHC
RNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKS
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
VLESMNDLIRRA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA