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The map label for this gene is mtnU [H]

Identifier: 109947554

GI number: 109947554

Start: 885996

End: 886829

Strand: Reverse

Name: mtnU [H]

Synonym: Hac_1019

Alternate gene names: 109947554

Gene position: 886829-885996 (Counterclockwise)

Preceding gene: 109947555

Following gene: 109947553

Centisome position: 57.07

GC content: 39.93

Gene sequence:

>834_bases
ATGCAATCCAAACCCTGCACTTTGAATGAAAACTTGCAACTAGCCCTTGATCTAGCCAAAGAAGCCCACAATAAAGGTGC
AAATCTCATTGTCTTGCCTGAACTTTTTGATAGCGGATATTGCGTGAATGATAAAGATAGTGGATTAGGGATAGATTTTA
AAGCCATAAAACATGGCGAGAAAACGCTAAAAAACGAGACTTTAAGAGCGTTAAGCGATTTTGCAAAGTCTAGTAAAGTG
CATGTGGTGGCATGCAGTATTGAAAAAAATAATAGAAAACTTTATGACAGTGCTTATATCGTTTCACCAGAAGGTAAAAT
CGTTGGTAAACACCGTAAGATCTATTTGTGGGGCGATGAAAAATCGCACTTCAAAAGGGGCAAAAAATACGAAATTTTCA
CGCTTGATTTTGGGGATTTTAGTGCGAAAGTGGGTTTGCAAATTTGCTATGAAATCGGCTTTGGCGTGGGCGCGAACATT
TTAGCGTTACAGGGGGCGGAGGTTTTAATCTATCCTAGTGCATTTGGAAGAGCTAGGGCTTATAATTGGGATTTATTGAG
CAAAGCTAGAGCGTTAGAAAATGGCTGTTTTGTGTGTGCATGCAATCATAGTGGGGAAGAAACGAACCCTAAATTAAAAC
AAACGCTAGAGTTTGCGGGAGATTCACGCATCATCGCACCCAATGGAAAAATCATCGTGCAAGCTACTAAACCCAACGAA
GTCATTATCGCCGATCTTGATTTAAACGAGGTCGCATCGCAACGCCAAAAAATCCCTTATTTACAAGATTTTGACACCAA
ACTCACTAAAAAGGGGTTTGGAAAACTCACTTAA

Upstream 100 bases:

>100_bases
TAATTCCTCTTCTTATAGAATAAAACAAAAATGGGAGTGGATTTTGAAAGAACAGGACTCAGCCAAAATACCAAGAATCC
TAAAAACCGCTGTGATTCAA

Downstream 100 bases:

>100_bases
CAAGGAGTGGTTATGGCAAAAGAAATTTTAGTGGCTTATGGCGTGGATATTGATGCGGTGGCTGGTTGGCTAGGGAGCTA
TGGTGGGGAGGATTCGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MQSKPCTLNENLQLALDLAKEAHNKGANLIVLPELFDSGYCVNDKDSGLGIDFKAIKHGEKTLKNETLRALSDFAKSSKV
HVVACSIEKNNRKLYDSAYIVSPEGKIVGKHRKIYLWGDEKSHFKRGKKYEIFTLDFGDFSAKVGLQICYEIGFGVGANI
LALQGAEVLIYPSAFGRARAYNWDLLSKARALENGCFVCACNHSGEETNPKLKQTLEFAGDSRIIAPNGKIIVQATKPNE
VIIADLDLNEVASQRQKIPYLQDFDTKLTKKGFGKLT

Sequences:

>Translated_277_residues
MQSKPCTLNENLQLALDLAKEAHNKGANLIVLPELFDSGYCVNDKDSGLGIDFKAIKHGEKTLKNETLRALSDFAKSSKV
HVVACSIEKNNRKLYDSAYIVSPEGKIVGKHRKIYLWGDEKSHFKRGKKYEIFTLDFGDFSAKVGLQICYEIGFGVGANI
LALQGAEVLIYPSAFGRARAYNWDLLSKARALENGCFVCACNHSGEETNPKLKQTLEFAGDSRIIAPNGKIIVQATKPNE
VIIADLDLNEVASQRQKIPYLQDFDTKLTKKGFGKLT
>Mature_277_residues
MQSKPCTLNENLQLALDLAKEAHNKGANLIVLPELFDSGYCVNDKDSGLGIDFKAIKHGEKTLKNETLRALSDFAKSSKV
HVVACSIEKNNRKLYDSAYIVSPEGKIVGKHRKIYLWGDEKSHFKRGKKYEIFTLDFGDFSAKVGLQICYEIGFGVGANI
LALQGAEVLIYPSAFGRARAYNWDLLSKARALENGCFVCACNHSGEETNPKLKQTLEFAGDSRIIAPNGKIIVQATKPNE
VIIADLDLNEVASQRQKIPYLQDFDTKLTKKGFGKLT

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=266, Percent_Identity=28.9473684210526, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI297632348, Length=269, Percent_Identity=25.2788104089219, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5031947, Length=269, Percent_Identity=25.2788104089219, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI297632350, Length=269, Percent_Identity=25.2788104089219, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786412, Length=242, Percent_Identity=28.9256198347107, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17533173, Length=252, Percent_Identity=23.8095238095238, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323383, Length=267, Percent_Identity=29.2134831460674, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322335, Length=290, Percent_Identity=26.551724137931, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355835, Length=243, Percent_Identity=31.2757201646091, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17933642, Length=258, Percent_Identity=25.1937984496124, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358471, Length=286, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30676; Mature: 30676

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKPCTLNENLQLALDLAKEAHNKGANLIVLPELFDSGYCVNDKDSGLGIDFKAIKHGE
CCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEHHHCCCCCEECCCCCCCCEEHHHHHCCH
KTLKNETLRALSDFAKSSKVHVVACSIEKNNRKLYDSAYIVSPEGKIVGKHRKIYLWGDE
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECEEEEECCCCCEEECEEEEEEECCC
KSHFKRGKKYEIFTLDFGDFSAKVGLQICYEIGFGVGANILALQGAEVLIYPSAFGRARA
HHHHHCCCEEEEEEEECCCCCHHHHHEEEEECCCCCCCEEEEECCCEEEEEECCCCCCEE
YNWDLLSKARALENGCFVCACNHSGEETNPKLKQTLEFAGDSRIIAPNGKIIVQATKPNE
CCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEEECCCCE
VIIADLDLNEVASQRQKIPYLQDFDTKLTKKGFGKLT
EEEEECCHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MQSKPCTLNENLQLALDLAKEAHNKGANLIVLPELFDSGYCVNDKDSGLGIDFKAIKHGE
CCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEHHHCCCCCEECCCCCCCCEEHHHHHCCH
KTLKNETLRALSDFAKSSKVHVVACSIEKNNRKLYDSAYIVSPEGKIVGKHRKIYLWGDE
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECEEEEECCCCCEEECEEEEEEECCC
KSHFKRGKKYEIFTLDFGDFSAKVGLQICYEIGFGVGANILALQGAEVLIYPSAFGRARA
HHHHHCCCEEEEEEEECCCCCHHHHHEEEEECCCCCCCEEEEECCCEEEEEECCCCCCEE
YNWDLLSKARALENGCFVCACNHSGEETNPKLKQTLEFAGDSRIIAPNGKIIVQATKPNE
CCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEEECCCCE
VIIADLDLNEVASQRQKIPYLQDFDTKLTKKGFGKLT
EEEEECCHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]