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The map label for this gene is neuA fragment 1 [H]

Identifier: 109947536

GI number: 109947536

Start: 870319

End: 871008

Strand: Reverse

Name: neuA fragment 1 [H]

Synonym: Hac_0995

Alternate gene names: 109947536

Gene position: 871008-870319 (Counterclockwise)

Preceding gene: 109947537

Following gene: 109947535

Centisome position: 56.05

GC content: 36.52

Gene sequence:

>690_bases
ATGAGAGTGATCGCTATTGTTTTGGCTAGAAGTTCTAGTAAAAGGATCAAGCATAAAAATACTATAGATTTTTTCAATAA
ACCCATGCTCGCTTACCCTATTGAAACGGCACTAAACTCCAAGATCTTTGAAAGAGTGTTTGTTTCTAGCGACAGCATGG
AGTATGTTGATCTAGCCAAAAATTATGGGGCGAGTTTTTTGAATCTACGCCCTAAAGTTTTAGCCAATGATAGGGCTACG
ACTTTAGAAGTGATGGCCTATCACATGGAAGAATTAGAATTAAAAGATAATGATATAGCGTGTTGTTTGTATGGCACTTC
AGTTTTTTTACAAAAAAAGCATTTACAATGCGCTTTTGAGACTTTAAAAGAAAATCAAAATGCGGACTATGTTTTCACAT
GCTCTCCATTTAGCGCTTCGCCCTATCGTTCTTTTAGCCTTGAAAATGGCGTTCAAATGGTCTTTAAAGAGTATTTAAAC
ACATGCACGCAAGATTTAAAAACGCTCTATCATGACGCAGGGTTGCTCTATATGGGGAAGGCTCAGGTCTTTAAAGAAAT
GCGACCTATTTTTAGCCAAAATTCTATCGCTTTAGAATTATCGCCATTAGAAGTCCAAGACATTGACACTTTAGAAGATT
TGGAATTAGCCAAGCTCAAATACAGCCGTTTAAAAAATTCATGCCAGTAA

Upstream 100 bases:

>100_bases
CGAATTTAGGGCATTTGAGCGATTCTAACAAAAAGAAATTCGCTGCTGATGCGATGGAAACCCAAATGCCTTATTGAAAA
GAGCGTTTAAAAATATAACT

Downstream 100 bases:

>100_bases
AAATTTTGTGCGATGCGTTTGTAACAAGCGGTTTAGGGCATGTGAGGCGTGGTGAAAAAATCCTTTCTTATGTAGAAAAA
TTAGGCGTTGAAGCGAGCCT

Product: CMP-N-acetylneuraminic acid synthetase fragment 1

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRVIAIVLARSSSKRIKHKNTIDFFNKPMLAYPIETALNSKIFERVFVSSDSMEYVDLAKNYGASFLNLRPKVLANDRAT
TLEVMAYHMEELELKDNDIACCLYGTSVFLQKKHLQCAFETLKENQNADYVFTCSPFSASPYRSFSLENGVQMVFKEYLN
TCTQDLKTLYHDAGLLYMGKAQVFKEMRPIFSQNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNSCQ

Sequences:

>Translated_229_residues
MRVIAIVLARSSSKRIKHKNTIDFFNKPMLAYPIETALNSKIFERVFVSSDSMEYVDLAKNYGASFLNLRPKVLANDRAT
TLEVMAYHMEELELKDNDIACCLYGTSVFLQKKHLQCAFETLKENQNADYVFTCSPFSASPYRSFSLENGVQMVFKEYLN
TCTQDLKTLYHDAGLLYMGKAQVFKEMRPIFSQNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNSCQ
>Mature_229_residues
MRVIAIVLARSSSKRIKHKNTIDFFNKPMLAYPIETALNSKIFERVFVSSDSMEYVDLAKNYGASFLNLRPKVLANDRAT
TLEVMAYHMEELELKDNDIACCLYGTSVFLQKKHLQCAFETLKENQNADYVFTCSPFSASPYRSFSLENGVQMVFKEYLN
TCTQDLKTLYHDAGLLYMGKAQVFKEMRPIFSQNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNSCQ

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26269; Mature: 26269

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIAIVLARSSSKRIKHKNTIDFFNKPMLAYPIETALNSKIFERVFVSSDSMEYVDLAK
CEEEEEEEECCCCCHHCCCCCHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYGASFLNLRPKVLANDRATTLEVMAYHMEELELKDNDIACCLYGTSVFLQKKHLQCAFE
HCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHHHH
TLKENQNADYVFTCSPFSASPYRSFSLENGVQMVFKEYLNTCTQDLKTLYHDAGLLYMGK
HHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECH
AQVFKEMRPIFSQNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNSCQ
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVIAIVLARSSSKRIKHKNTIDFFNKPMLAYPIETALNSKIFERVFVSSDSMEYVDLAK
CEEEEEEEECCCCCHHCCCCCHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYGASFLNLRPKVLANDRATTLEVMAYHMEELELKDNDIACCLYGTSVFLQKKHLQCAFE
HCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHHHH
TLKENQNADYVFTCSPFSASPYRSFSLENGVQMVFKEYLNTCTQDLKTLYHDAGLLYMGK
HHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECH
AQVFKEMRPIFSQNSIALELSPLEVQDIDTLEDLELAKLKYSRLKNSCQ
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549035 [H]