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The map label for this gene is 109947233

Identifier: 109947233

GI number: 109947233

Start: 575380

End: 576891

Strand: Direct

Name: 109947233

Synonym: Hac_0656

Alternate gene names: NA

Gene position: 575380-576891 (Clockwise)

Preceding gene: 109947232

Following gene: 109947249

Centisome position: 37.03

GC content: 41.27

Gene sequence:

>1512_bases
ATGAAAAAGATCTATTATGCTAGAGGGCAAGCCGTTTTAAAAAGTGCTTCAGCTAAAGCTAAATTGATGGAATTTCAAGC
AAAATCTTTTGTGGAAGCCGAAGAGATGCGCATGAAAAGTCAAGAATGCAAATTGCAACAACAATATGAAAATAAGAATT
TGCAACTCAAAGCCCATTTTGACAAAAAAGAAGCGTATTTGAAGCATTTAGAAGCGCAACACAAAGAATTCGTAAGAGAC
GAAAAACGCTATTTGGAAAAGGAAAAACAAGAGCTTGAAAAAGAGCGCCAAATTTTAGAACAAGAAAAAGAAAATTTTAA
AAAACAGTACGCTACCTGCAAAGAAAATCAATCCAAAGCACTAGATGTGATGCTCAATTACATGGCTTACACTAAAGAAG
AAATTAAAAGCATGATTTTAAAGCAATTAGAAGAAGAACTAGAAGCGCAAAAAAGCGCATTAATCAGGCGCTATGAAAAA
GAAGCCAAGGAAGAGAGTAAGAAAAAATCGTATGCAATTTTAGCGGAAGCGACAGCCCGTTTTGCAGGCAATTATGCGAT
AGAGAATTTCACAAACCGCATCGCTTTGCCGTGCTCAGAGTATATTGGCCGTGTGATAGGAAAAGATGGGAAAAATATTG
AGGCGTTTAAAAAGATCAGTGGGGTGGATATAGAATTTAGCGAAGGCGATAAGGAATTGTGCTTGTCTAGTTTCAATATT
TTTAGGCGTGAAGTGGCGAGCGAGACGCTTAAGATTTTAATAGAAGACGGCCGTATCCAGCCTAACCGGATTGAAGAAGT
TTATCACAGAGTTGTGCGCAACATGGAAAAGGAATTGCTTTCTGAGGGGCAGAGCGTGGTGTTGGAATTGGAGCTTGGGG
CTATGGAAGATGAGCTTAAAATTTTACTAGGTAAAATGCGTTATCGCTCTAGTTTTGGGCAAAACGCTTTACAGCATTCT
AAAGAAGTTGCCCTTTTAGCCGGCTTGATTGCAGAGCAGCTTGGAGGGGATAAAAAGCTCGCTAGAAGAGCCGGTATTTT
GCATGATATTGGTAAGGCGCTCACTCAAGAGCTTGGGAGAGATCATGTGAGTTTGGGCGTTGAGGTGTGTAAGCGTAATA
AAGAAGATCCGGTCGTTATCAATGCGATCTATGCCCACCATGGGCATGAAGAGATTATGAGTATAGAGTGTGCGAGCGTA
TGCGCAGCTGATGCACTTTCTGCGGGGCGTCCTGGGGCAAGAAGAAAGAGTGATGAAGAATACGCTAAACGCATGCAAGC
TTTAGAAGAGATTGCACTAGGGTTTGAAGGGGTTGAAAAGGCGTATGCGATGGAGAGCGGGCGAGAATTGAGAGTGATTG
TCAAATCCAATCAAGTTAGGGATAATCAAGTGCCAATTATTGCAAGAAAGATCGCTAAAAAGATAGAAGAGAGTGCTCAA
TATGTAGGCGAAGTGGGTGTGCAAGTGGTGCGAGAAAGTCGTTTCAAAACCACAGCTACGCTCAAGCAATAA

Upstream 100 bases:

>100_bases
AAGAATAATAAAAGGAAATATTATGGGCAACGGGTTAATTTACATTTCATTAGAAGTCATTGTAGCGTGTTTGATCAGTG
CTCTAGCAATGTATTATGTG

Downstream 100 bases:

>100_bases
GCGTTTTTAAGCCTTTTTCCCACACCTTTTCCAAATGCCTTTAGAAAAAACTTTATAATAAATGAGCGAGCGGAAAAAAG
TCTCTAGCGTGATCACCGCA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKKIYYARGQAVLKSASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLKAHFDKKEAYLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQYATCKENQSKALDVMLNYMAYTKEEIKSMILKQLEEELEAQKSALIRRYEK
EAKEESKKKSYAILAEATARFAGNYAIENFTNRIALPCSEYIGRVIGKDGKNIEAFKKISGVDIEFSEGDKELCLSSFNI
FRREVASETLKILIEDGRIQPNRIEEVYHRVVRNMEKELLSEGQSVVLELELGAMEDELKILLGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVSLGVEVCKRNKEDPVVINAIYAHHGHEEIMSIECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALGFEGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ

Sequences:

>Translated_503_residues
MKKIYYARGQAVLKSASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLKAHFDKKEAYLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQYATCKENQSKALDVMLNYMAYTKEEIKSMILKQLEEELEAQKSALIRRYEK
EAKEESKKKSYAILAEATARFAGNYAIENFTNRIALPCSEYIGRVIGKDGKNIEAFKKISGVDIEFSEGDKELCLSSFNI
FRREVASETLKILIEDGRIQPNRIEEVYHRVVRNMEKELLSEGQSVVLELELGAMEDELKILLGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVSLGVEVCKRNKEDPVVINAIYAHHGHEEIMSIECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALGFEGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ
>Mature_503_residues
MKKIYYARGQAVLKSASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLKAHFDKKEAYLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQYATCKENQSKALDVMLNYMAYTKEEIKSMILKQLEEELEAQKSALIRRYEK
EAKEESKKKSYAILAEATARFAGNYAIENFTNRIALPCSEYIGRVIGKDGKNIEAFKKISGVDIEFSEGDKELCLSSFNI
FRREVASETLKILIEDGRIQPNRIEEVYHRVVRNMEKELLSEGQSVVLELELGAMEDELKILLGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRDHVSLGVEVCKRNKEDPVVINAIYAHHGHEEIMSIECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALGFEGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_HELAH (Q17Y14)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664461.1
- ProteinModelPortal:   Q17Y14
- STRING:   Q17Y14
- GeneID:   4176657
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0656
- NMPDR:   fig|382638.8.peg.638
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- ProtClustDB:   PRK12704
- BioCyc:   HACI382638:HAC_0656-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 57500; Mature: 57500

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12929dd4)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYYARGQAVLKSASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLKAHF
CCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DKKEAYLKHLEAQHKEFVRDEKRYLEKEKQELEKERQILEQEKENFKKQYATCKENQSKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LDVMLNYMAYTKEEIKSMILKQLEEELEAQKSALIRRYEKEAKEESKKKSYAILAEATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGNYAIENFTNRIALPCSEYIGRVIGKDGKNIEAFKKISGVDIEFSEGDKELCLSSFNI
HHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHH
FRREVASETLKILIEDGRIQPNRIEEVYHRVVRNMEKELLSEGQSVVLELELGAMEDELK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
ILLGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
DHVSLGVEVCKRNKEDPVVINAIYAHHGHEEIMSIECASVCAADALSAGRPGARRKSDEE
HHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
YAKRMQALEEIALGFEGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YVGEVGVQVVRESRFKTTATLKQ
HHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MKKIYYARGQAVLKSASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLKAHF
CCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DKKEAYLKHLEAQHKEFVRDEKRYLEKEKQELEKERQILEQEKENFKKQYATCKENQSKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LDVMLNYMAYTKEEIKSMILKQLEEELEAQKSALIRRYEKEAKEESKKKSYAILAEATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGNYAIENFTNRIALPCSEYIGRVIGKDGKNIEAFKKISGVDIEFSEGDKELCLSSFNI
HHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHH
FRREVASETLKILIEDGRIQPNRIEEVYHRVVRNMEKELLSEGQSVVLELELGAMEDELK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
ILLGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
DHVSLGVEVCKRNKEDPVVINAIYAHHGHEEIMSIECASVCAADALSAGRPGARRKSDEE
HHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
YAKRMQALEEIALGFEGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YVGEVGVQVVRESRFKTTATLKQ
HHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA