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The map label for this gene is atpA

Identifier: 109947167

GI number: 109947167

Start: 511650

End: 513161

Strand: Direct

Name: atpA

Synonym: Hac_0580

Alternate gene names: 109947167

Gene position: 511650-513161 (Clockwise)

Preceding gene: 109947166

Following gene: 109947168

Centisome position: 32.93

GC content: 43.65

Gene sequence:

>1512_bases
ATGTCCCAACTAAAATTGGAAGAAATCAGCTCGGTTATTGAAGAAAAGATCAAGAATTTTGAACTTGATTGCGATATGGC
TGAAGTCGGCAAGGTCGTTTCATACGCTGATGGTGTGGCTAAGATTTATGGCTTAAATGGTGTGATGTCGTATGAAGTGT
TGGAGTTTGAAACAGGAGATAAAGGCGTTGCGGCTAACTTAGAAGAAGATAGCGTTGGCGTGATTGTGTTTGGTTTTGGC
AACAATATTAAAGAGGGGACGAGCGTTAAACGCACAAAGAGTTTGATGAAAGTCCCTGTTGGCGATGCAGTTGTTGGGCG
CGTGTTGAACGCTTTGGGTGAGCCTATTGATGGCAAGGGCGAGATAGAAACGAATGAGTTTAGCCTCATAGAGCAAAAAG
CCCCAGGCATTATGGACAGAAAATCTGTGCATGAGCCTTTACAAACTGGGATTAAAGCCATTGATGCGTTAGTGCCTATT
GGGCGTGGGCAGAGGGAGTTGATCATTGGGGATAAACAAACCGGTAAAACCACTGTAGCAATAGATACGATCATCAACCA
AAAAGGGCAAAATGTGATCTGCATTTATGTGGCTATTGGTCAAAAAGAATCCACCGTCGCGCAAGTGGTCCGTAAATTAG
AAGAATACGGAGCGATGGAATACAGCGTTGTGGTTAACGCTTCAGCTTCTGATTCGGCTGCGATGCAATATTTAGCCCCT
TATGCGGGTGTGGCTATGGGGGAATACTTTAGAGATCATGCCCGCCATGCCCTAATCATTTATGATGATTTGAGTAAGCA
TGCCGTCGCTTACAGAGAAATTTCTTTGATTTTAAGAAGACCTCCAGGTAGGGAAGCTTTTCCTGGCGATGTTTTTTATA
TCCACTCACGGCTTTTAGAAAGAGCGGCTAAAGTTTGCGATGAAAAAGGTGCAGGATCTTTAACCGCGCTCCCTATTGTG
GAAACTCAAGCGGGCGATGTTTCAGCCTATATCCCTACGAATATCATTTCCATTACAGACGGACAAATTTTCTTAGAAAC
GGATTTGTTTTATTCAGGGATCCGCCCTGCTATCAATGTAGGCTTGTCGGTTTCAAGGGTTGGAGGGGCCGCTCAAATCA
AAGCCACCAAGCAAGTTTCAGGGACTTTGCGCTTGGATTTAGCGCAATACAGAGAGTTGCAAGCCTTCACGCAATTCGCT
TCTGATTTAGATGAAGCGAGTAAAAAGCAATTAGAAAGAGGGCAACGCATGGTAGAAGTGCTCAAACAAGCCCCTTATTC
GCCCTTACCCATTGAAAAGCAAGTGGTCATTATTTATGCCGGGGCTAAAGGCTTTTTGGATAGCGTGAGCGTGAAAAAAG
TCGTGGATTTTGAAGAGCGGCTATACCCTTTCTTGGAAGCAAAATACCCTCAAGTATTAGAAGAAATCCACATTAAAAAA
GCGTTAGATAAGGATTTAGAAGCCATGCTAAAAAAAGCTTTAGAGGAATTCAAGCTCACTTATAGCGAGTAG

Upstream 100 bases:

>100_bases
AACTTGGATTTAGAAATAGGCTTTTCTAAGGAAGAGATTTTAAAGAAAATAGAAAAACAGGTTATTCAATCTATTTAATC
AATCTAAGGAGATAAAGATA

Downstream 100 bases:

>100_bases
GAGACGGCTAGGATATGGCAAATTTAAGAGACATTAGAAAGAAAATTGGAAGCGTTAAGAACACGCAAAAAATTACGCAT
GCGATGAAACTCGTTTCCAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKIYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFG
NNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPI
GRGQRELIIGDKQTGKTTVAIDTIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVVNASASDSAAMQYLAP
YAGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKVCDEKGAGSLTALPIV
ETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFA
SDLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEERLYPFLEAKYPQVLEEIHIKK
ALDKDLEAMLKKALEEFKLTYSE

Sequences:

>Translated_503_residues
MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKIYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFG
NNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPI
GRGQRELIIGDKQTGKTTVAIDTIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVVNASASDSAAMQYLAP
YAGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKVCDEKGAGSLTALPIV
ETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFA
SDLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEERLYPFLEAKYPQVLEEIHIKK
ALDKDLEAMLKKALEEFKLTYSE
>Mature_502_residues
SQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKIYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFGN
NIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDKQTGKTTVAIDTIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVVNASASDSAAMQYLAPY
AGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKVCDEKGAGSLTALPIVE
TQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFAS
DLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEERLYPFLEAKYPQVLEEIHIKKA
LDKDLEAMLKKALEEFKLTYSE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=59.6385542168675, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=59.6385542168675, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI19913428, Length=299, Percent_Identity=29.4314381270903, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI19913426, Length=298, Percent_Identity=27.8523489932886, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI32189394, Length=402, Percent_Identity=24.6268656716418, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI19913424, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=55.7729941291585, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1790170, Length=385, Percent_Identity=25.1948051948052, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788251, Length=279, Percent_Identity=30.8243727598566, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=58.7649402390438, Blast_Score=614, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=58.7649402390438, Blast_Score=612, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=55.1792828685259, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17510931, Length=297, Percent_Identity=28.956228956229, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=29.0969899665552, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=420, Percent_Identity=23.5714285714286, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=46.4788732394366, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=58.1673306772908, Blast_Score=622, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=29.4314381270903, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=428, Percent_Identity=25.9345794392523, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658560, Length=502, Percent_Identity=60.1593625498008, Blast_Score=615, Evalue=1e-176,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.9036544850498, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.9036544850498, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.9036544850498, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28574560, Length=428, Percent_Identity=27.3364485981308, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24638766, Length=395, Percent_Identity=24.3037974683544, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24583988, Length=254, Percent_Identity=26.3779527559055, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583986, Length=254, Percent_Identity=26.3779527559055, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583984, Length=254, Percent_Identity=26.3779527559055, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583992, Length=254, Percent_Identity=26.7716535433071, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20129479, Length=384, Percent_Identity=26.3020833333333, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_HELAH (Q17Y80)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664395.1
- ProteinModelPortal:   Q17Y80
- SMR:   Q17Y80
- STRING:   Q17Y80
- GeneID:   4177102
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0580
- NMPDR:   fig|382638.8.peg.563
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q17Y80
- ProtClustDB:   PRK09281
- BioCyc:   HACI382638:HAC_0580-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55154; Mature: 55023

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKIYGLNGVMSYEVLEFETGD
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHEECCCEEEEEEEEEECCC
KGVAANLEEDSVGVIVFGFGNNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKG
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
EIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDKQTGKTTVA
CEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEE
IDTIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVVNASASDSAAMQYLAP
EEHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHH
YAGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLE
HHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHH
RAAKVCDEKGAGSLTALPIVETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINV
HHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHHHHCCCHHHHC
GLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASKKQLERGQRMVEV
CEEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEERLYPFLEAKYPQVLEEIHIKK
HHHCCCCCCCCCCEEEEEEECCCCCHHCCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHH
ALDKDLEAMLKKALEEFKLTYSE
HHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKIYGLNGVMSYEVLEFETGD
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHEECCCEEEEEEEEEECCC
KGVAANLEEDSVGVIVFGFGNNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKG
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
EIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDKQTGKTTVA
CEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEE
IDTIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVVNASASDSAAMQYLAP
EEHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHH
YAGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLE
HHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHH
RAAKVCDEKGAGSLTALPIVETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINV
HHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHHHHCCCHHHHC
GLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASKKQLERGQRMVEV
CEEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEERLYPFLEAKYPQVLEEIHIKK
HHHCCCCCCCCCCEEEEEEECCCCCHHCCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHH
ALDKDLEAMLKKALEEFKLTYSE
HHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA