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The map label for this gene is obgE

Identifier: 109947154

GI number: 109947154

Start: 495956

End: 497038

Strand: Direct

Name: obgE

Synonym: Hac_0564

Alternate gene names: 109947154

Gene position: 495956-497038 (Clockwise)

Preceding gene: 109947153

Following gene: 109947155

Centisome position: 31.92

GC content: 43.95

Gene sequence:

>1083_bases
GTGTTTGTAGACAGCGTGGAAATTATCATCGCTTCGGGTAAGGGGGGGCCTGGAATGGTGAGTTTTAGGCGAGAAAAGTT
TGTCATTAAAGGCGGTCCTGATGGGGGTGATGGAGGCGATGGAGGCGATGTGTATTTTGAAGTGGATAACAATACCGACA
CTCTAGCGAGTTTTAGGGGCACTAAACACCATAAGGCTAAAAACGGGGCTCCAGGAGGCACGCGAAATTGCACGGGCAAA
AAAGGCGAAGACAAGATTATTATCGTACCGCCAGGAACGCAAGTTTTTGCAGATGGTGCTTTATGGCTTGATTTGATCAC
GCCTAAAGAAAGGGTGTTAGCCTTAAAAGGAGGTAAAGGGGGGTTAGGGAATGCACACTTTAAAAGCGCGACTAAACAAC
AACCCACTTACGCGCAAAAAGGCTTGGAGGGGGTTGAAAAATGCGTGCGTTTGGAATTAAAGCTCATCGCTGATATAGGG
TTAGTGGGCTTCCCTAATGCGGGTAAATCCACGCTCATTTCCACAATCTCTAACGCTAAACCTAAAATCGCTCATTATGA
ATTTACGACTCTAGTGCCTAATTTAGGGGTCGTGAGCGTAGATGAAAAAAGCGGGTTTTTAATGGCGGATATTCCTGGCA
TTATTGAAGGGGCTAGTGAGGGAAAAGGCTTGGGGATTAGCTTTTTAAAGCACATTGAACGCACCAAAGTTTTAGCCTTT
GTTTTAGACGCTTCTAGGCTGGATTTGGGTATTAAAGAGCAATACAAGCGCTTGAGGTTGGAGTTGGAAAAATTTTCACC
CGCTTTGGCTAACAAGCCTTTTGGGGTGTTGCTCAATAAATGCGATGTTGCAGAAGATATTGATACCATGACGAAAGATT
TTTGCACCTTTTTAAACTTGAAAGTGCAAAAACTGGAGGCGTTTGATTTAGAGCCGTATCTTGGGTTTTTGCACCCTAAA
TTGATGGGCAATTTTGAAAAGGATCTTAATGAAAAATCCGCGCTCTTTATCTTACCCCTTTCAGCGGTTAGCGCCTTAAA
CACGCATGCACTTAAATTTGTGTTGTTGGAAGCGTTACCATAA

Upstream 100 bases:

>100_bases
TAAGCGCCCCAAAGCACCCCTATACGCAGAAATTGCTCAATGCCGTGCCGCATTTGGAAAAATCCATGCAAAGATTTGCT
GAATAAAGGGGATTTTAGCC

Downstream 100 bases:

>100_bases
AACGCTATTCTTAAACCAATCCATTCAAATAAAGGCGAGAAATGAAAAGATTTGTTTTGTTTTTATCACTCATGGGTGTT
TGTGTTTGCGTTCAAGCTTA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCTGK
KGEDKIIIVPPGTQVFADGALWLDLITPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIG
LVGFPNAGKSTLISTISNAKPKIAHYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAF
VLDASRLDLGIKEQYKRLRLELEKFSPALANKPFGVLLNKCDVAEDIDTMTKDFCTFLNLKVQKLEAFDLEPYLGFLHPK
LMGNFEKDLNEKSALFILPLSAVSALNTHALKFVLLEALP

Sequences:

>Translated_360_residues
MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCTGK
KGEDKIIIVPPGTQVFADGALWLDLITPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIG
LVGFPNAGKSTLISTISNAKPKIAHYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAF
VLDASRLDLGIKEQYKRLRLELEKFSPALANKPFGVLLNKCDVAEDIDTMTKDFCTFLNLKVQKLEAFDLEPYLGFLHPK
LMGNFEKDLNEKSALFILPLSAVSALNTHALKFVLLEALP
>Mature_360_residues
MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCTGK
KGEDKIIIVPPGTQVFADGALWLDLITPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIG
LVGFPNAGKSTLISTISNAKPKIAHYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAF
VLDASRLDLGIKEQYKRLRLELEKFSPALANKPFGVLLNKCDVAEDIDTMTKDFCTFLNLKVQKLEAFDLEPYLGFLHPK
LMGNFEKDLNEKSALFILPLSAVSALNTHALKFVLLEALP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=291, Percent_Identity=39.8625429553265, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI111955139, Length=350, Percent_Identity=36.5714285714286, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI111955063, Length=206, Percent_Identity=38.3495145631068, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4758796, Length=126, Percent_Identity=39.6825396825397, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4557537, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789574, Length=294, Percent_Identity=48.9795918367347, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=40.809968847352, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=346, Percent_Identity=30.9248554913295, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71981008, Length=124, Percent_Identity=37.0967741935484, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=38.135593220339, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=41.2371134020619, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321612, Length=124, Percent_Identity=37.9032258064516, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=37.3015873015873, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=42.1052631578947, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=370, Percent_Identity=33.2432432432432, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356473, Length=90, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17981711, Length=126, Percent_Identity=38.0952380952381, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_HELAH (Q17Y93)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664382.1
- ProteinModelPortal:   Q17Y93
- SMR:   Q17Y93
- STRING:   Q17Y93
- GeneID:   4176465
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0564
- NMPDR:   fig|382638.8.peg.548
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   HACI382638:HAC_0564-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 38784; Mature: 38784

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRG
CCCCCEEEEEEECCCCCCCEEEECEEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHCCC
TKHHKAKNGAPGGTRNCTGKKGEDKIIIVPPGTQVFADGALWLDLITPKERVLALKGGKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEEEECCCCEEEEEECCCC
GLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAK
CCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCC
PKIAHYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAF
CCEEEEEEEHHCCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHEEEE
VLDASRLDLGIKEQYKRLRLELEKFSPALANKPFGVLLNKCDVAEDIDTMTKDFCTFLNL
EECHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHEECCCCHHHHHHHHHHHHHHHCC
KVQKLEAFDLEPYLGFLHPKLMGNFEKDLNEKSALFILPLSAVSALNTHALKFVLLEALP
EEEEHEEECCCHHHHHHCHHHHCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRG
CCCCCEEEEEEECCCCCCCEEEECEEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHCCC
TKHHKAKNGAPGGTRNCTGKKGEDKIIIVPPGTQVFADGALWLDLITPKERVLALKGGKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEEEECCCCEEEEEECCCC
GLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAK
CCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCC
PKIAHYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAF
CCEEEEEEEHHCCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHEEEE
VLDASRLDLGIKEQYKRLRLELEKFSPALANKPFGVLLNKCDVAEDIDTMTKDFCTFLNL
EECHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHEECCCCHHHHHHHHHHHHHHHCC
KVQKLEAFDLEPYLGFLHPKLMGNFEKDLNEKSALFILPLSAVSALNTHALKFVLLEALP
EEEEHEEECCCHHHHHHCHHHHCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA