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The map label for this gene is dppA [H]

Identifier: 109947149

GI number: 109947149

Start: 490752

End: 492392

Strand: Direct

Name: dppA [H]

Synonym: Hac_0559

Alternate gene names: 109947149

Gene position: 490752-492392 (Clockwise)

Preceding gene: 109947148

Following gene: 109947150

Centisome position: 31.58

GC content: 40.59

Gene sequence:

>1641_bases
ATGAATAGCGTTTTTATTAGGGGCTTGTCCCTTTTTGTTTTATTGTTTTTTGGGGTTTTTTTAAAAGCTTCAGGAAACAC
CACTCTTAATCCGTCCGATGTTTCTGTTGAAGAGCAAAAGCGTTTTGGAGGCGTTTTAGTTTTTGCTAGAGGTGCTGATG
GCTCAAGCATGGATCCTGCATTAGCAACCGATGGCGAAAGCTATGTGGCAACGAGCAATATTTATGACACGCTCGTGCAA
TTCAAATACGGCACCACAGAAATTGAACCCGGATTAGCCACAAGTTGGGATATATCCCCAGATGGTCTTGTATATACCTT
TCACTTACGAAAAGGGGTTTATTTCCACCAAACGAAATATTGGAATAAAAAAGTAGAGTTTAGTGCTAAAGATGTGCTGT
TTTCGTTTGAGCGCCAAATGGATAAGGCTAAACGATATTATAGCCCAGGGGCTAAGAGCTATAAGTATTGGGAAGGCATG
GGCATGTCTCATATCATTAAGAGCATTGAAGCTTTAGATGACTATACTATCAAGTTCACGCTTAATGGGCCAGAAGCCCC
TTTTCTAGCGAATTTGGGCATGGATTTTTTGAGCATTTTGAGTAAGGATTATGCTGATTATTTAGCCCAAAATAACAGAA
AAGACGAATTGGCTAAAAAGCCTGTTGGGACAGGGCCTTTCAAATTCTTTTTATGGAATAAAGACGAAAAAATCATTTTG
GTCAAAAATCAAGATTATTGGGGCCCTAAAGCTTATTTAGATAAGGTGGTGGTGCGCACCATTCCTAATTCTTCCACTCG
CGCTTTAGCGTTAAGAACCGGCGAGGTGATGCTTATGACTGGGCCTAATCTCAATGAAGTGGAGCAATTGGAAAAAGTCC
CCAATATCGTGGTGGATAAAAGCCCGGGGTTGTTGGCGAGTTGGCTTTCAATGAACACGCAAAAAAAATATTTCAATAAC
CCTTTAGTGCGTTTAGCCATCAACCATGCGATCAATGTGGATGATTATATCAAGGTGCTTTATGAAGGCTTTGCCCAAAA
AATGGTCAATCCTTTTCCGCCCACCATATGGGGTTATAACCAAAATATCAAGCCTTATGAATACGATTTGAAAAAAGCTA
AGGAATTGCTGAAACAAGCGGGCTATCCTAACGGCTTTAAAACCACTATTTTTACCACTGCCACTCGCAACCCAAAAGGA
GCGGTATTCATACAAGCAAGCCTGGCTAAAATTGGCATTGATGTGAAAATTGAAGTGTATGAGTGGGGGGCTTATTTGAA
AAGGACAGGCTTAGGCGAACATGAAATGGCGTTTGCAGGCTGGATGGCGGACATTGCAGATCCGGATAATTTCCTATACA
CCTTATGGAGCGAGCAAGCCGCATCAGCCATACCCACTCAAAACACTTCCTTTTATAAGAATAAGGAGTTTTCAAATTTG
CTGGTAAAGGCTAAACGAGTTTCAGATCAAAAAGAGAGAGAAGCTCTCTACTTAAAAGCTCAAGAAATCATCCATAAAGA
CGCTCCTTATGTGCCTTTAGCCTATCCTTATTCAGTGGTGCCTCACTTATCTAAAGTCAAAGGTTATAAGACTACAGGAG
TGAATGTGAATCGCTTCTTTAAGGTGTATTTAGAAAAATAA

Upstream 100 bases:

>100_bases
GAATTAAGTTTTTTGGTGTTTATTAACCACCTATAAATGCGATAAAGTATTTATAATTTAGTTCTCTACTCTTTGTAGAA
TATGTTGTGGAGGCTACTTT

Downstream 100 bases:

>100_bases
AAGGGGTTGTATGCTGAGTTTTATCATCAAGCGCATTTTGTGGGCGATCCCCACGCTGTTTGGAGTGAGCGTCATCGTGT
TTATGATGGTGCATTTAGTG

Product: dipeptide transport system substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MNSVFIRGLSLFVLLFFGVFLKASGNTTLNPSDVSVEEQKRFGGVLVFARGADGSSMDPALATDGESYVATSNIYDTLVQ
FKYGTTEIEPGLATSWDISPDGLVYTFHLRKGVYFHQTKYWNKKVEFSAKDVLFSFERQMDKAKRYYSPGAKSYKYWEGM
GMSHIIKSIEALDDYTIKFTLNGPEAPFLANLGMDFLSILSKDYADYLAQNNRKDELAKKPVGTGPFKFFLWNKDEKIIL
VKNQDYWGPKAYLDKVVVRTIPNSSTRALALRTGEVMLMTGPNLNEVEQLEKVPNIVVDKSPGLLASWLSMNTQKKYFNN
PLVRLAINHAINVDDYIKVLYEGFAQKMVNPFPPTIWGYNQNIKPYEYDLKKAKELLKQAGYPNGFKTTIFTTATRNPKG
AVFIQASLAKIGIDVKIEVYEWGAYLKRTGLGEHEMAFAGWMADIADPDNFLYTLWSEQAASAIPTQNTSFYKNKEFSNL
LVKAKRVSDQKEREALYLKAQEIIHKDAPYVPLAYPYSVVPHLSKVKGYKTTGVNVNRFFKVYLEK

Sequences:

>Translated_546_residues
MNSVFIRGLSLFVLLFFGVFLKASGNTTLNPSDVSVEEQKRFGGVLVFARGADGSSMDPALATDGESYVATSNIYDTLVQ
FKYGTTEIEPGLATSWDISPDGLVYTFHLRKGVYFHQTKYWNKKVEFSAKDVLFSFERQMDKAKRYYSPGAKSYKYWEGM
GMSHIIKSIEALDDYTIKFTLNGPEAPFLANLGMDFLSILSKDYADYLAQNNRKDELAKKPVGTGPFKFFLWNKDEKIIL
VKNQDYWGPKAYLDKVVVRTIPNSSTRALALRTGEVMLMTGPNLNEVEQLEKVPNIVVDKSPGLLASWLSMNTQKKYFNN
PLVRLAINHAINVDDYIKVLYEGFAQKMVNPFPPTIWGYNQNIKPYEYDLKKAKELLKQAGYPNGFKTTIFTTATRNPKG
AVFIQASLAKIGIDVKIEVYEWGAYLKRTGLGEHEMAFAGWMADIADPDNFLYTLWSEQAASAIPTQNTSFYKNKEFSNL
LVKAKRVSDQKEREALYLKAQEIIHKDAPYVPLAYPYSVVPHLSKVKGYKTTGVNVNRFFKVYLEK
>Mature_546_residues
MNSVFIRGLSLFVLLFFGVFLKASGNTTLNPSDVSVEEQKRFGGVLVFARGADGSSMDPALATDGESYVATSNIYDTLVQ
FKYGTTEIEPGLATSWDISPDGLVYTFHLRKGVYFHQTKYWNKKVEFSAKDVLFSFERQMDKAKRYYSPGAKSYKYWEGM
GMSHIIKSIEALDDYTIKFTLNGPEAPFLANLGMDFLSILSKDYADYLAQNNRKDELAKKPVGTGPFKFFLWNKDEKIIL
VKNQDYWGPKAYLDKVVVRTIPNSSTRALALRTGEVMLMTGPNLNEVEQLEKVPNIVVDKSPGLLASWLSMNTQKKYFNN
PLVRLAINHAINVDDYIKVLYEGFAQKMVNPFPPTIWGYNQNIKPYEYDLKKAKELLKQAGYPNGFKTTIFTTATRNPKG
AVFIQASLAKIGIDVKIEVYEWGAYLKRTGLGEHEMAFAGWMADIADPDNFLYTLWSEQAASAIPTQNTSFYKNKEFSNL
LVKAKRVSDQKEREALYLKAQEIIHKDAPYVPLAYPYSVVPHLSKVKGYKTTGVNVNRFFKVYLEK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=535, Percent_Identity=38.8785046728972, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1787551, Length=507, Percent_Identity=29.3885601577909, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787052, Length=493, Percent_Identity=32.0486815415822, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1787762, Length=493, Percent_Identity=30.4259634888438, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1787495, Length=522, Percent_Identity=27.5862068965517, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789887, Length=481, Percent_Identity=26.8191268191268, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1789397, Length=537, Percent_Identity=25.6983240223464, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081878, Length=489, Percent_Identity=26.7893660531697, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61921; Mature: 61921

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVFIRGLSLFVLLFFGVFLKASGNTTLNPSDVSVEEQKRFGGVLVFARGADGSSMDPA
CCCEEHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCC
LATDGESYVATSNIYDTLVQFKYGTTEIEPGLATSWDISPDGLVYTFHLRKGVYFHQTKY
CCCCCCCEEEEHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEHHH
WNKKVEFSAKDVLFSFERQMDKAKRYYSPGAKSYKYWEGMGMSHIIKSIEALDDYTIKFT
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEEEE
LNGPEAPFLANLGMDFLSILSKDYADYLAQNNRKDELAKKPVGTGPFKFFLWNKDEKIIL
ECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCEEEE
VKNQDYWGPKAYLDKVVVRTIPNSSTRALALRTGEVMLMTGPNLNEVEQLEKVPNIVVDK
EECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCCCEEEEC
SPGLLASWLSMNTQKKYFNNPLVRLAINHAINVDDYIKVLYEGFAQKMVNPFPPTIWGYN
CCCHHHHHHHCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCC
QNIKPYEYDLKKAKELLKQAGYPNGFKTTIFTTATRNPKGAVFIQASLAKIGIDVKIEVY
CCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEHHHCCCEEEEEEE
EWGAYLKRTGLGEHEMAFAGWMADIADPDNFLYTLWSEQAASAIPTQNTSFYKNKEFSNL
ECCHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCCCCCCCCCCCHHHH
LVKAKRVSDQKEREALYLKAQEIIHKDAPYVPLAYPYSVVPHLSKVKGYKTTGVNVNRFF
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCEECCCCHHHEE
KVYLEK
EEEECC
>Mature Secondary Structure
MNSVFIRGLSLFVLLFFGVFLKASGNTTLNPSDVSVEEQKRFGGVLVFARGADGSSMDPA
CCCEEHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCC
LATDGESYVATSNIYDTLVQFKYGTTEIEPGLATSWDISPDGLVYTFHLRKGVYFHQTKY
CCCCCCCEEEEHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEHHH
WNKKVEFSAKDVLFSFERQMDKAKRYYSPGAKSYKYWEGMGMSHIIKSIEALDDYTIKFT
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEEEE
LNGPEAPFLANLGMDFLSILSKDYADYLAQNNRKDELAKKPVGTGPFKFFLWNKDEKIIL
ECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCEEEE
VKNQDYWGPKAYLDKVVVRTIPNSSTRALALRTGEVMLMTGPNLNEVEQLEKVPNIVVDK
EECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCCCEEEEC
SPGLLASWLSMNTQKKYFNNPLVRLAINHAINVDDYIKVLYEGFAQKMVNPFPPTIWGYN
CCCHHHHHHHCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCC
QNIKPYEYDLKKAKELLKQAGYPNGFKTTIFTTATRNPKGAVFIQASLAKIGIDVKIEVY
CCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEHHHCCCEEEEEEE
EWGAYLKRTGLGEHEMAFAGWMADIADPDNFLYTLWSEQAASAIPTQNTSFYKNKEFSNL
ECCHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCCCCCCCCCCCHHHH
LVKAKRVSDQKEREALYLKAQEIIHKDAPYVPLAYPYSVVPHLSKVKGYKTTGVNVNRFF
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCEECCCCHHHEE
KVYLEK
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]