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The map label for this gene is pabB [H]

Identifier: 109947144

GI number: 109947144

Start: 484327

End: 486018

Strand: Direct

Name: pabB [H]

Synonym: Hac_0553

Alternate gene names: 109947144

Gene position: 484327-486018 (Clockwise)

Preceding gene: 109947143

Following gene: 109947145

Centisome position: 31.17

GC content: 35.7

Gene sequence:

>1692_bases
ATGATTTTTGGGGATTTTAAATATCAAAAGAGTATTAAAAAACTAACAGCGACTAATTTTAACGAGCTTAAAAACGCCTT
GGATTTTATCTCTCAAAATAGGGGGAATGGGTATTTTGTGGGGTATCTTTTGTATGAAGCACGCCTAGCGTTTTTAGATG
AAACTTTTCAAAGCCAAACCCCTTTTTTGTATTTTGAACAATTTTTAGAAAGGAAAAAATACTCTTTAGAGCCTTTAAAA
GAGCATGCGTTTTACCCTAAAATCCATAGCTCTTTAGATCAAAAAACTTATTTCAAGCAGTTTAAAACTATTAAAGAGCA
TCTAAAAAACGGCGATACCTATCAAGTGAATCTCACAATGGATTTATTTTTAAACACCAAAGCCAAACTAAAGCGCGTTT
TTTGCGAGGTAGCGTGCAACCAAAACACGCCTTTTAAGGCGTTTATAGAAAATGAGTTTTGGAGTGTTTTAAGCTTTTCG
CCAGAGTTGTTTTTTGAATTGGAGTTTTTAGATACAGCCATTAAGATTATCACAAAGCCCATGAAAGGCACGATCGCTCG
CTCTAATGACCCTTTAATAGATGAAAAAAACCGATATTTTTTGCAAAATGATGACAAAAATAGAAGCGAAAATGTGATGA
TTGTGGATTTACTGCGTAACGATTTGAGCCGTTTAGCTTTAAAAAATAGCGTGAAAGTCAATCAATTGTTTGAAATCATA
AGTCTCTCTAGTGTGTATCAAATGATAAGCGAGATTGAAGCGCAATTGCCCCTAAAAACAAGCTTATTTGAGATTTTCAA
GGCGTTATTCCCTTGCGGATCGGTTACCGGATGCCCTAAAATCAAAACCATGCAAATCATTGAAAACTTAGAAAAACGCC
CTAGGGGGGTGTATTGCGGAGCGATAGGCATGGTTGAAGAAAAAAAAGCCCTTTTTAGCGTGCCCATCCGCACTTTAGAA
AAAAGAGCGCACGAAGATGTTTTGCATTTGGGGGTGGGGAGTGGGGTTACTTATAAAAGTGGAGCGTTAGAGGAATATGA
AGAGAGTTTTTTAAAATCCTTTTTTGTGATGCCCAAAATAGAATTTGAGATTGTAGAGACGATGAAGGTCATAAAAATCG
ATCAAAAATTAGAGATTAAAAATAAAAACGCCCATAAAGAACGCTTGATTAACAGCGCTCAATATTTTAATTTCCAATAC
GATGAAAATCTTTTGGACTTTGAATTAGAAAAGGAAGGGGTTTTAAGGGTTTTACTCAATAAAAAGGGCAAGCTCATTAA
AGAGTATAAAAATTTAGAGCCTTTAAAAAGCCTGGAAGTGCGTTTGAGTGAGACCCCCATTGACAAACACAATGATTTTT
TATACCACAAGATTACTTATGCCCCTTTTTATCAAAAGGCTCGAGCACTCATTAAAAAAGGCGTTATTTTTGATGAAATC
TTTTATAACCAAGATTTTAAGCTCACCGAAGGAGCTAGGAGCAATCTTATTTTAGAAATCCACAACAAGCTTCTAACCCC
TTATTTTAGCGCGGGTGCATTAAATGGGACAGGTGTGATGGGGCTGTTAAAAAAGGGTCTTGTTGAACATGCCCCTTTAA
AATTACATGATTTGCAAAGAGCGACTAAAATCTATTGCATCAACGCACTATATGGCTTAGTGGAAGTGAAAATAAAACGG
ATTTTACCATAA

Upstream 100 bases:

>100_bases
CAGAGAAGAAGATCTAGGATTAGAGGGCTTGAGAAGGGCTAAAATGAGCTATAATCCGGTGTTTTTGATAGACAAATACG
AAGCCGTTGCTAGAAATTAA

Downstream 100 bases:

>100_bases
AATAGAGTTACTAAAATCTATTTTTTAAAACAAGTTACTAAATTCCACCAAATAAGTTAAATTCCACCAATTAATAATCA
TATAATCATAATGATTAAAG

Product: para-aminobenzoate synthetase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MIFGDFKYQKSIKKLTATNFNELKNALDFISQNRGNGYFVGYLLYEARLAFLDETFQSQTPFLYFEQFLERKKYSLEPLK
EHAFYPKIHSSLDQKTYFKQFKTIKEHLKNGDTYQVNLTMDLFLNTKAKLKRVFCEVACNQNTPFKAFIENEFWSVLSFS
PELFFELEFLDTAIKIITKPMKGTIARSNDPLIDEKNRYFLQNDDKNRSENVMIVDLLRNDLSRLALKNSVKVNQLFEII
SLSSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVTGCPKIKTMQIIENLEKRPRGVYCGAIGMVEEKKALFSVPIRTLE
KRAHEDVLHLGVGSGVTYKSGALEEYEESFLKSFFVMPKIEFEIVETMKVIKIDQKLEIKNKNAHKERLINSAQYFNFQY
DENLLDFELEKEGVLRVLLNKKGKLIKEYKNLEPLKSLEVRLSETPIDKHNDFLYHKITYAPFYQKARALIKKGVIFDEI
FYNQDFKLTEGARSNLILEIHNKLLTPYFSAGALNGTGVMGLLKKGLVEHAPLKLHDLQRATKIYCINALYGLVEVKIKR
ILP

Sequences:

>Translated_563_residues
MIFGDFKYQKSIKKLTATNFNELKNALDFISQNRGNGYFVGYLLYEARLAFLDETFQSQTPFLYFEQFLERKKYSLEPLK
EHAFYPKIHSSLDQKTYFKQFKTIKEHLKNGDTYQVNLTMDLFLNTKAKLKRVFCEVACNQNTPFKAFIENEFWSVLSFS
PELFFELEFLDTAIKIITKPMKGTIARSNDPLIDEKNRYFLQNDDKNRSENVMIVDLLRNDLSRLALKNSVKVNQLFEII
SLSSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVTGCPKIKTMQIIENLEKRPRGVYCGAIGMVEEKKALFSVPIRTLE
KRAHEDVLHLGVGSGVTYKSGALEEYEESFLKSFFVMPKIEFEIVETMKVIKIDQKLEIKNKNAHKERLINSAQYFNFQY
DENLLDFELEKEGVLRVLLNKKGKLIKEYKNLEPLKSLEVRLSETPIDKHNDFLYHKITYAPFYQKARALIKKGVIFDEI
FYNQDFKLTEGARSNLILEIHNKLLTPYFSAGALNGTGVMGLLKKGLVEHAPLKLHDLQRATKIYCINALYGLVEVKIKR
ILP
>Mature_563_residues
MIFGDFKYQKSIKKLTATNFNELKNALDFISQNRGNGYFVGYLLYEARLAFLDETFQSQTPFLYFEQFLERKKYSLEPLK
EHAFYPKIHSSLDQKTYFKQFKTIKEHLKNGDTYQVNLTMDLFLNTKAKLKRVFCEVACNQNTPFKAFIENEFWSVLSFS
PELFFELEFLDTAIKIITKPMKGTIARSNDPLIDEKNRYFLQNDDKNRSENVMIVDLLRNDLSRLALKNSVKVNQLFEII
SLSSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVTGCPKIKTMQIIENLEKRPRGVYCGAIGMVEEKKALFSVPIRTLE
KRAHEDVLHLGVGSGVTYKSGALEEYEESFLKSFFVMPKIEFEIVETMKVIKIDQKLEIKNKNAHKERLINSAQYFNFQY
DENLLDFELEKEGVLRVLLNKKGKLIKEYKNLEPLKSLEVRLSETPIDKHNDFLYHKITYAPFYQKARALIKKGVIFDEI
FYNQDFKLTEGARSNLILEIHNKLLTPYFSAGALNGTGVMGLLKKGLVEHAPLKLHDLQRATKIYCINALYGLVEVKIKR
ILP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=295, Percent_Identity=34.9152542372881, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI1787518, Length=265, Percent_Identity=25.6603773584906, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=270, Percent_Identity=28.8888888888889, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324361, Length=338, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 65374; Mature: 65374

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGDFKYQKSIKKLTATNFNELKNALDFISQNRGNGYFVGYLLYEARLAFLDETFQSQT
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCC
PFLYFEQFLERKKYSLEPLKEHAFYPKIHSSLDQKTYFKQFKTIKEHLKNGDTYQVNLTM
CHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DLFLNTKAKLKRVFCEVACNQNTPFKAFIENEFWSVLSFSPELFFELEFLDTAIKIITKP
EEEECCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHCC
MKGTIARSNDPLIDEKNRYFLQNDDKNRSENVMIVDLLRNDLSRLALKNSVKVNQLFEII
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHH
SLSSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVTGCPKIKTMQIIENLEKRPRGVYCG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
AIGMVEEKKALFSVPIRTLEKRAHEDVLHLGVGSGVTYKSGALEEYEESFLKSFFVMPKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EFEIVETMKVIKIDQKLEIKNKNAHKERLINSAQYFNFQYDENLLDFELEKEGVLRVLLN
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHEEEEECCCCCCEEECHHHHHHHHHC
KKGKLIKEYKNLEPLKSLEVRLSETPIDKHNDFLYHKITYAPFYQKARALIKKGVIFDEI
CCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCHHHHH
FYNQDFKLTEGARSNLILEIHNKLLTPYFSAGALNGTGVMGLLKKGLVEHAPLKLHDLQR
HCCCCCEECCCCCCCEEHEEHHHHHCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
ATKIYCINALYGLVEVKIKRILP
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFGDFKYQKSIKKLTATNFNELKNALDFISQNRGNGYFVGYLLYEARLAFLDETFQSQT
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCC
PFLYFEQFLERKKYSLEPLKEHAFYPKIHSSLDQKTYFKQFKTIKEHLKNGDTYQVNLTM
CHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DLFLNTKAKLKRVFCEVACNQNTPFKAFIENEFWSVLSFSPELFFELEFLDTAIKIITKP
EEEECCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHCC
MKGTIARSNDPLIDEKNRYFLQNDDKNRSENVMIVDLLRNDLSRLALKNSVKVNQLFEII
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHH
SLSSVYQMISEIEAQLPLKTSLFEIFKALFPCGSVTGCPKIKTMQIIENLEKRPRGVYCG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
AIGMVEEKKALFSVPIRTLEKRAHEDVLHLGVGSGVTYKSGALEEYEESFLKSFFVMPKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EFEIVETMKVIKIDQKLEIKNKNAHKERLINSAQYFNFQYDENLLDFELEKEGVLRVLLN
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHEEEEECCCCCCEEECHHHHHHHHHC
KKGKLIKEYKNLEPLKSLEVRLSETPIDKHNDFLYHKITYAPFYQKARALIKKGVIFDEI
CCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCHHHHH
FYNQDFKLTEGARSNLILEIHNKLLTPYFSAGALNGTGVMGLLKKGLVEHAPLKLHDLQR
HCCCCCEECCCCCCCEEHEEHHHHHCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
ATKIYCINALYGLVEVKIKRILP
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]