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The map label for this gene is yhfN [H]

Identifier: 109947072

GI number: 109947072

Start: 419925

End: 421148

Strand: Direct

Name: yhfN [H]

Synonym: Hac_0473

Alternate gene names: 109947072

Gene position: 419925-421148 (Clockwise)

Preceding gene: 109947070

Following gene: 109947073

Centisome position: 27.02

GC content: 37.5

Gene sequence:

>1224_bases
ATGCTTGATGTATGGATAGATATGATAATTTTTATTTTCTATTTGCTCTTTTTTACGGCTCCTCATATTCTAGGCGATGT
TTTGCAAGTGTATTTTATCCGCCAAAAGCTTTGCGAGAAGCCTATTTTGCTCCCCAAAAAGGATTATGAAAAAGCGGGCT
ATTATGCCATTAGAAAAATGCAATTATCTATTGTTTCTCAATTTTTGGACGGCATCATCTTCGCTGGCTGGGTCTTTTTT
GGTCTGACGCATTTAGAAGATTTAACGCATTATTTAAACCTTTCTGAAACGCTAGGTTATGTGGTGTTTGCATTGTCATT
TTTAGCGATTCAAAGCCTTTTATCCTTACCGATTAGCTACTATACCACCATGCATTTGGATAAGGGATTTGGTTTTTCTA
AAGTGAGTTTATCGTTGTTTTTTAAGGATTTTTTCAAAAGCTTGTTGCTCACTTTAGGCGTGGGGTTGTTATTGATTTAC
ATTCTTGTTATGATCATTCAACATGTAGAGCATTGGGAGATTAGCTCGTTTGTCGTCGTGTTTGCTTTTATGATTTTGGC
TAATCTTTTTTACCCTAAAATCACACAGCTTTTCAACCAATTCACCCCCTTAAACAATAGGAATTTGGAAAAGCAAATTG
AAAGCATGATGGATAAAGTGGGTTTTAAATCCCAAGGCATTTTTGTGATGGATGCTAGTAAGAGAGATGGGTGCTTGAAT
GCGTATTTTGGAGAGTTGGGTAAAAATAAACGAGTGGTATTGTTTGACACTTTGTTTTCTAAGGTTGGGACAGATGGGCT
TTTAGCGATTTTAGGGCATGAGTTGGGGCATTTCAAAAATAAGGATTTGCTGAAAGGTTTAGGGATTATGGGAAGTTTGC
TCGCTTTGGCATTTGTGATCATTTCCTATTTGCCGCCAATCGTCTTTGAAGGCTTTAATGTTTCAGAGACGCCAGCGAGT
TTGATCACCATTTTACTTTTGTTTTTGCCGGTATTTTCCTTTTACGCCATGCCTTTGATCGGATTTTTAGCCGCAAGTAA
TGAATACCATGCCGACAAATTTGGGGCGAGTTTAAGCTCTAAAGAAACTTTAGCCAAAGCTTTAGTGTCTATCGCCAATG
AAAATAAGACTTTCCCTTATTCGCACCCCTTCTATGTTTTCTTGCATTTCACACACCCGCCACTTTTAGAGTGCTTGAAA
GCTTTGGATTACAAAATTGAATGA

Upstream 100 bases:

>100_bases
GATAGTAAATGTTTAAAAAACACTGTTACAATCATCACTTATTGCAGTTTTACTGATATTGCAGTTTTACTGATAAATTG
ATTAAAAAGGAGTTTAGAAC

Downstream 100 bases:

>100_bases
CCCTTTCACAAGCCCTAAACAAAGCCAAAAAAGGATTATCCCAAAAAGGTTTTAGGGGGGGGTTAGAGTCTGAAATTTTG
TTAGGCTTTGTTTTGCAAAA

Product: integral membrane zinc-metalloprotease

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLDVWIDMIIFIFYLLFFTAPHILGDVLQVYFIRQKLCEKPILLPKKDYEKAGYYAIRKMQLSIVSQFLDGIIFAGWVFF
GLTHLEDLTHYLNLSETLGYVVFALSFLAIQSLLSLPISYYTTMHLDKGFGFSKVSLSLFFKDFFKSLLLTLGVGLLLIY
ILVMIIQHVEHWEISSFVVVFAFMILANLFYPKITQLFNQFTPLNNRNLEKQIESMMDKVGFKSQGIFVMDASKRDGCLN
AYFGELGKNKRVVLFDTLFSKVGTDGLLAILGHELGHFKNKDLLKGLGIMGSLLALAFVIISYLPPIVFEGFNVSETPAS
LITILLLFLPVFSFYAMPLIGFLAASNEYHADKFGASLSSKETLAKALVSIANENKTFPYSHPFYVFLHFTHPPLLECLK
ALDYKIE

Sequences:

>Translated_407_residues
MLDVWIDMIIFIFYLLFFTAPHILGDVLQVYFIRQKLCEKPILLPKKDYEKAGYYAIRKMQLSIVSQFLDGIIFAGWVFF
GLTHLEDLTHYLNLSETLGYVVFALSFLAIQSLLSLPISYYTTMHLDKGFGFSKVSLSLFFKDFFKSLLLTLGVGLLLIY
ILVMIIQHVEHWEISSFVVVFAFMILANLFYPKITQLFNQFTPLNNRNLEKQIESMMDKVGFKSQGIFVMDASKRDGCLN
AYFGELGKNKRVVLFDTLFSKVGTDGLLAILGHELGHFKNKDLLKGLGIMGSLLALAFVIISYLPPIVFEGFNVSETPAS
LITILLLFLPVFSFYAMPLIGFLAASNEYHADKFGASLSSKETLAKALVSIANENKTFPYSHPFYVFLHFTHPPLLECLK
ALDYKIE
>Mature_407_residues
MLDVWIDMIIFIFYLLFFTAPHILGDVLQVYFIRQKLCEKPILLPKKDYEKAGYYAIRKMQLSIVSQFLDGIIFAGWVFF
GLTHLEDLTHYLNLSETLGYVVFALSFLAIQSLLSLPISYYTTMHLDKGFGFSKVSLSLFFKDFFKSLLLTLGVGLLLIY
ILVMIIQHVEHWEISSFVVVFAFMILANLFYPKITQLFNQFTPLNNRNLEKQIESMMDKVGFKSQGIFVMDASKRDGCLN
AYFGELGKNKRVVLFDTLFSKVGTDGLLAILGHELGHFKNKDLLKGLGIMGSLLALAFVIISYLPPIVFEGFNVSETPAS
LITILLLFLPVFSFYAMPLIGFLAASNEYHADKFGASLSSKETLAKALVSIANENKTFPYSHPFYVFLHFTHPPLLECLK
ALDYKIE

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=377, Percent_Identity=29.1777188328912, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17505484, Length=402, Percent_Identity=25.8706467661692, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322577, Length=318, Percent_Identity=33.9622641509434, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI19922414, Length=383, Percent_Identity=28.9817232375979, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24654305, Length=401, Percent_Identity=25.1870324189526, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46244; Mature: 46244

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVWIDMIIFIFYLLFFTAPHILGDVLQVYFIRQKLCEKPILLPKKDYEKAGYYAIRKM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
QLSIVSQFLDGIIFAGWVFFGLTHLEDLTHYLNLSETLGYVVFALSFLAIQSLLSLPISY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YTTMHLDKGFGFSKVSLSLFFKDFFKSLLLTLGVGLLLIYILVMIIQHVEHWEISSFVVV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAFMILANLFYPKITQLFNQFTPLNNRNLEKQIESMMDKVGFKSQGIFVMDASKRDGCLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
AYFGELGKNKRVVLFDTLFSKVGTDGLLAILGHELGHFKNKDLLKGLGIMGSLLALAFVI
HHHHHHCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ISYLPPIVFEGFNVSETPASLITILLLFLPVFSFYAMPLIGFLAASNEYHADKFGASLSS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCH
KETLAKALVSIANENKTFPYSHPFYVFLHFTHPPLLECLKALDYKIE
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]