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The map label for this gene is csd [H]

Identifier: 109947065

GI number: 109947065

Start: 411815

End: 413137

Strand: Direct

Name: csd [H]

Synonym: Hac_0463

Alternate gene names: 109947065

Gene position: 411815-413137 (Clockwise)

Preceding gene: 109947064

Following gene: 109947066

Centisome position: 26.5

GC content: 39.08

Gene sequence:

>1323_bases
GTGCAAGCGTTTTTAAATAGGAGTTTCGCTCCCTTACTTAACCCTAACGAAAGCCCTTTAGAGCAGGTTAAATCTAGTAT
TATTTTAAAAAAAGGGGTGTCTTATTTTGACTGGGGGGCTTCAGGTTTAGCGAGTGCTTTAGTGGAAAAGCGCGTGAAAT
CTCTACTGCCTTATTATGCGAACCCTCATTCTATCGCTTCTAAACATGCGATTTTAATGGGTATGCTTTTAAATGAGTGT
CAAGAGAGGTTAAAGTGCTCTTTAAATTTAAGCGAAGATCATTGCGTTTTGAGTGCAGGGTATGGGGCGAGCTCAGCGAT
TAAGAAATTTCAAGAAATTTTAGGGGTGTGTATCCCTTCAAAAACAAAGAAGAATTTAGAGCCGTATTTAAAGGATATGG
CTTTAAAGCGTGTGATTGTAGGGCCTTATGAGCATCATTCCAATGAAATTAGCTGGCGTGAAGGCTTGTGTGAAGTGGTG
CGTATCCCTTTAAATGGGCATGGCTTATTGGATTTAGAAATTTTAGAGCAACATTTAAAAAAATCCCCCAATAGTTTGGT
TTCTATAAGTGCAGCTTCTAATGTAACTGGGTTGCTTACGCCCTTAAAAGAAGTTTCATTATTGTGTAAGAAATACCAAG
CTACTTTAGCTTTGGATTTAGCGAATTTTAGCACGCATGCTAACCCTAAAGATTGCGAATATAAAACCGGTTTTTATGCC
CCTCATAAGCTTTTAGGGGGTGTTGGGGGGTGTGGTCTTTTGGGTATTTCTAAAGATTTGATTGACACTCAAATCGCTCC
GAGTTTTAGTGCAGGGGGTGTGATTAAATACGCTAACCATACAAGGCATGAATTTATTGATGAATTGCCTTTGAGAGAAG
AGTTTGGCACGCCAGGGTTGTTGCAATTTTATAGGAGCGCTTTGGCGTATCAATTAAGAGATGAATGCGGTTTGGACTTT
ATCCATAAGAAAGAAAATAACCTTTTAAGAGTGCTTATGCATGGTTTAAAAGACTTGCCCGCCATCAATATTTATGGGAA
TTTAACAGCACATCGTGTGGGGGTGGTGGCTTTTAATATTGGAGGGATTTCGCCTTATGATTTAGCGAGAGTTTTAAGTT
ATGAATACGCTATTGAAACTCGGGCAGGTTGCTCTTGTGCAGGGCCTTATGGGCATGATTTATTGAATCTTAACGCCCAA
AAGTCAAGCGATTTTAATACTAAACCTGGATGGCTTAGAGTGAGCTTACACTTCACGCATTCCATAAACGATATTGATTA
TTTGCTAGATAGCTTGAAAAAAGCGGTTAAAAAATTGCGTTAA

Upstream 100 bases:

>100_bases
GCTTTTAACCAATGTGGGTAAAAACGCAGGGCAGGAGGTGATGCATTTGCATTTTCATATTTTAAGCGGGGATAAACATT
AAAAGCGTTGGTGGTGTTTT

Downstream 100 bases:

>100_bases
GCTAAAACTATTTTTAAGGAAAAATTTGGATATTTTAGATTTAAACAAAGCACAAGTGGCACAACAAGATAAGCAAGAGG
CAGAAATTAAAGAAAAAGAG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQAFLNRSFAPLLNPNESPLEQVKSSIILKKGVSYFDWGASGLASALVEKRVKSLLPYYANPHSIASKHAILMGMLLNEC
QERLKCSLNLSEDHCVLSAGYGASSAIKKFQEILGVCIPSKTKKNLEPYLKDMALKRVIVGPYEHHSNEISWREGLCEVV
RIPLNGHGLLDLEILEQHLKKSPNSLVSISAASNVTGLLTPLKEVSLLCKKYQATLALDLANFSTHANPKDCEYKTGFYA
PHKLLGGVGGCGLLGISKDLIDTQIAPSFSAGGVIKYANHTRHEFIDELPLREEFGTPGLLQFYRSALAYQLRDECGLDF
IHKKENNLLRVLMHGLKDLPAINIYGNLTAHRVGVVAFNIGGISPYDLARVLSYEYAIETRAGCSCAGPYGHDLLNLNAQ
KSSDFNTKPGWLRVSLHFTHSINDIDYLLDSLKKAVKKLR

Sequences:

>Translated_440_residues
MQAFLNRSFAPLLNPNESPLEQVKSSIILKKGVSYFDWGASGLASALVEKRVKSLLPYYANPHSIASKHAILMGMLLNEC
QERLKCSLNLSEDHCVLSAGYGASSAIKKFQEILGVCIPSKTKKNLEPYLKDMALKRVIVGPYEHHSNEISWREGLCEVV
RIPLNGHGLLDLEILEQHLKKSPNSLVSISAASNVTGLLTPLKEVSLLCKKYQATLALDLANFSTHANPKDCEYKTGFYA
PHKLLGGVGGCGLLGISKDLIDTQIAPSFSAGGVIKYANHTRHEFIDELPLREEFGTPGLLQFYRSALAYQLRDECGLDF
IHKKENNLLRVLMHGLKDLPAINIYGNLTAHRVGVVAFNIGGISPYDLARVLSYEYAIETRAGCSCAGPYGHDLLNLNAQ
KSSDFNTKPGWLRVSLHFTHSINDIDYLLDSLKKAVKKLR
>Mature_440_residues
MQAFLNRSFAPLLNPNESPLEQVKSSIILKKGVSYFDWGASGLASALVEKRVKSLLPYYANPHSIASKHAILMGMLLNEC
QERLKCSLNLSEDHCVLSAGYGASSAIKKFQEILGVCIPSKTKKNLEPYLKDMALKRVIVGPYEHHSNEISWREGLCEVV
RIPLNGHGLLDLEILEQHLKKSPNSLVSISAASNVTGLLTPLKEVSLLCKKYQATLALDLANFSTHANPKDCEYKTGFYA
PHKLLGGVGGCGLLGISKDLIDTQIAPSFSAGGVIKYANHTRHEFIDELPLREEFGTPGLLQFYRSALAYQLRDECGLDF
IHKKENNLLRVLMHGLKDLPAINIYGNLTAHRVGVVAFNIGGISPYDLARVLSYEYAIETRAGCSCAGPYGHDLLNLNAQ
KSSDFNTKPGWLRVSLHFTHSINDIDYLLDSLKKAVKKLR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=306, Percent_Identity=28.4313725490196, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789175, Length=310, Percent_Identity=23.2258064516129, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211090, Length=451, Percent_Identity=25.2771618625277, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 48574; Mature: 48574

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFLNRSFAPLLNPNESPLEQVKSSIILKKGVSYFDWGASGLASALVEKRVKSLLPYYA
CCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCC
NPHSIASKHAILMGMLLNECQERLKCSLNLSEDHCVLSAGYGASSAIKKFQEILGVCIPS
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCC
KTKKNLEPYLKDMALKRVIVGPYEHHSNEISWREGLCEVVRIPLNGHGLLDLEILEQHLK
CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHEECCCCCCCEEEHHHHHHHHH
KSPNSLVSISAASNVTGLLTPLKEVSLLCKKYQATLALDLANFSTHANPKDCEYKTGFYA
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCC
PHKLLGGVGGCGLLGISKDLIDTQIAPSFSAGGVIKYANHTRHEFIDELPLREEFGTPGL
HHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCHHHCCCCHH
LQFYRSALAYQLRDECGLDFIHKKENNLLRVLMHGLKDLPAINIYGNLTAHRVGVVAFNI
HHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEC
GGISPYDLARVLSYEYAIETRAGCSCAGPYGHDLLNLNAQKSSDFNTKPGWLRVSLHFTH
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEEEC
SINDIDYLLDSLKKAVKKLR
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQAFLNRSFAPLLNPNESPLEQVKSSIILKKGVSYFDWGASGLASALVEKRVKSLLPYYA
CCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCC
NPHSIASKHAILMGMLLNECQERLKCSLNLSEDHCVLSAGYGASSAIKKFQEILGVCIPS
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCC
KTKKNLEPYLKDMALKRVIVGPYEHHSNEISWREGLCEVVRIPLNGHGLLDLEILEQHLK
CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHEECCCCCCCEEEHHHHHHHHH
KSPNSLVSISAASNVTGLLTPLKEVSLLCKKYQATLALDLANFSTHANPKDCEYKTGFYA
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCC
PHKLLGGVGGCGLLGISKDLIDTQIAPSFSAGGVIKYANHTRHEFIDELPLREEFGTPGL
HHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCHHHCCCCHH
LQFYRSALAYQLRDECGLDFIHKKENNLLRVLMHGLKDLPAINIYGNLTAHRVGVVAFNI
HHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEC
GGISPYDLARVLSYEYAIETRAGCSCAGPYGHDLLNLNAQKSSDFNTKPGWLRVSLHFTH
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEEEC
SINDIDYLLDSLKKAVKKLR
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]