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The map label for this gene is hpcD [H]

Identifier: 108812519

GI number: 108812519

Start: 2640939

End: 2641337

Strand: Reverse

Name: hpcD [H]

Synonym: YPN_2358

Alternate gene names: 108812519

Gene position: 2641337-2640939 (Counterclockwise)

Preceding gene: 108812520

Following gene: 108812518

Centisome position: 58.25

GC content: 48.37

Gene sequence:

>399_bases
ATGGCGCATTTCTACGCAGAATGTACTGACAACATCCGTGAACAGGCCGAATTACCCGTCTTGTTTTCTAACGTAAATCA
AACTCTGGTGAACACGGGTCTTTTCCCATTGGCAGGTATTCGCAGCCGTGCCATTTGGCTGGATACCTGGCAAATGGCGG
ATGGACAGCAAGACTACGCTTTTGTCCATATGACGCTAAAAATAGGCTACGGACGCAGTATCGAGCACCGACAGGCGGTC
GGAAAGACATTGTTTGCCTTGATTCAAGCGCATTTCGCAGCCCTGATGTCCCAACGTTATCTGGCTTTGTCGTTCGTCAT
AGAGGAGCTGGATCCAACGCTTAGCTTTAAACAGAACAATGCTCATACATTGTTCCAACAGGGAACCTCTGCATGTTAG

Upstream 100 bases:

>100_bases
GTTTGTCACCGATCTGTTTGCCAGTTCGGGTACCGGGCAGGTGAATGCGATATTCCCATTGGCCGTTTACGGGTAAATCT
CACTGATAAGGGGAGAGGCT

Downstream 100 bases:

>100_bases
CTCAAAAGACGATTATCCAAATTGCACAACAGCTATACCAAGCTGAACAGTGTGGTGAACAAATCCGCCAAGTCTCGCTC
GATTACCCCATGATAACCAT

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAHFYAECTDNIREQAELPVLFSNVNQTLVNTGLFPLAGIRSRAIWLDTWQMADGQQDYAFVHMTLKIGYGRSIEHRQAV
GKTLFALIQAHFAALMSQRYLALSFVIEELDPTLSFKQNNAHTLFQQGTSAC

Sequences:

>Translated_132_residues
MAHFYAECTDNIREQAELPVLFSNVNQTLVNTGLFPLAGIRSRAIWLDTWQMADGQQDYAFVHMTLKIGYGRSIEHRQAV
GKTLFALIQAHFAALMSQRYLALSFVIEELDPTLSFKQNNAHTLFQQGTSAC
>Mature_131_residues
AHFYAECTDNIREQAELPVLFSNVNQTLVNTGLFPLAGIRSRAIWLDTWQMADGQQDYAFVHMTLKIGYGRSIEHRQAVG
KTLFALIQAHFAALMSQRYLALSFVIEELDPTLSFKQNNAHTLFQQGTSAC

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 14911; Mature: 14780

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFYAECTDNIREQAELPVLFSNVNQTLVNTGLFPLAGIRSRAIWLDTWQMADGQQDYA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEE
FVHMTLKIGYGRSIEHRQAVGKTLFALIQAHFAALMSQRYLALSFVIEELDPTLSFKQNN
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
AHTLFQQGTSAC
CHHHHHCCCCCC
>Mature Secondary Structure 
AHFYAECTDNIREQAELPVLFSNVNQTLVNTGLFPLAGIRSRAIWLDTWQMADGQQDYA
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEE
FVHMTLKIGYGRSIEHRQAVGKTLFALIQAHFAALMSQRYLALSFVIEELDPTLSFKQNN
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
AHTLFQQGTSAC
CHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]