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The map label for this gene is flhA [H]

Identifier: 108812494

GI number: 108812494

Start: 2614336

End: 2616414

Strand: Reverse

Name: flhA [H]

Synonym: YPN_2333

Alternate gene names: 108812494

Gene position: 2616414-2614336 (Counterclockwise)

Preceding gene: 108812495

Following gene: 108812493

Centisome position: 57.7

GC content: 51.8

Gene sequence:

>2079_bases
ATGGCTAATTTGGCCGCCCTGCTACGTTTACCGGGCAATTTTAAAGACACACAGTGGCAAATTCTCGCTGGGCCAATCCT
GATCTTAATGATCTTGTCGATGATGATTTTGCCTCTGCCTCCATTCGCCTTGGATTTGTTGTTTACCTTTAATATTGCAC
TTTCCATCATGGTGTTACTGGTGGCCATGTTCACCCAGCGCACACTGGATTTTGCCGCCTTTCCGACCATCCTGTTGTTC
TCTACTTTATTGCGTCTATCACTAAACGTGGCTTCCACGCGTATTATTCTGATGGATGGTCACACCGGGGGCGCGGCGGC
CGGGCGAGTGGTTGAGGCATTTGGTCACTTCCTGGTTGGTGGTAATTTTGCCATTGGTATTGTGGTCTTTGTCATTCTGG
TGGTGATCAACTTTATGGTGATCACCAAAGGGGCAGGGCGTATTGCTGAAGTGGGTGCCCGTTTCGTTTTGGATGGTATG
CCCGGTAAACAGATGGCGATCGACGCTGATTTAAATGCCGGATTGATCGGCGAAGATGAAGCGAAAAAACGCCGCTCTGA
CGTTACGCAAGAGGCTGACTTCTACGGTTCGATGGACGGGGCCAGTAAATTTGTTCGCGGTGATGCGGTTGCTGGTTTGC
TGATCATGGTGATTAACGTGGTGGGGGGGCTACTGGTCGGCGTGCTTCAGCACAACATGGCTTTTGGTCATGCAGCAGAA
ACCTATACCTTGCTCACCATTGGCGATGGTTTGGTTGCTCAAATCCCTGCGCTGGTAATTTCGACCGCCTCAGGGGTGAT
TGTCACTCGCGTCAGTACTGATCAAGACGTTGGCCAGCAAATGGTCACCCAACTGTTCAACAACCCACGGGTGATGGTAT
TAAGTGCCAGCGTACTGGGTCTGCTGGGAATGGTGCCTGGGATGCCGAATTTTGTCTTCCTACTATTTACCGCAGCATTA
TTGGCCTTGGCTTGGCGCTTACGTGGTAAACAAACACAGCAGCCTGTGGCAGTAGAAGCACCCGTGGTGCAAGATCAGCA
ACAGGGCGCAGAGGCGACATGGGCAGATGTTCAACTGGAAGATCCGCTGGGGATGGAAGTGGGTTACCGCTTGATACCGA
TGGTGGATTTCCAGCAAAACGGTGAATTATTGGGCCGAATTCGTAGCATTCGCAAAAAATTTGCGCAAGAGATGGGCTAT
CTACCGCCAGTCGTGCATATTCGCGATAACTTGGAATTACCCCCTGCTAATTATCGGATATTAATGAAAGGGGTCGAAAT
TGGCAGTGGTGAGGCGCACCCAGGGCGCTGGCTGGCGATTAACCCTGGTAACGCCGTTGGTACATTACCGGGTGAAGCTA
CCCACGACCCGGCCTTCGGTCTGGCGGCGGTGTGGATAGAGAGTGCGTTACGTGAGCAGGCACAAATTCAGGGCTTTACC
GTGGTTGAGGCCAGCACGGTGGTGGCGACGCATTTGAACCATGTGCTCAGCCAATATGCCAACGAGTTGTTCGGCCGTCA
GGAAACTCAACAGCTCCTTGATCGTGTGACGCAAGAGATGCCAAAGTTGACCGAAGACTTTATCCCTGGGGTGGTGACAT
TAACCACGTTACATAAAGTTTTGCAAAATCTGTTAATGGAGCGGGTCTCGATCCGCGACATGCGCACCATTATTGAAACA
CTGGCCGAACATGCGCCAAACCAGGCTGATCCTTACGAATTAACCGCGACAGTGCGAGTGGCATTAGGGCGTTCAATTGC
GCAGCAGTGGTTCCCTGGGAATGGTGAAATTCAGGTTATCGGGTTGGATGCTGCCTTGGAGCGCTTATTATTACAAGCTC
TGCAAGGGGGGAGTGGCTTGGAGCCGGGTCTGGCTGATCGTCTGCTGGATCAATCCAAACAAGCGTTGCAACGCCAAGAG
ATGCTAGGCGCACCGCCTGTATTATTGGTTAATCATGCACTACGGGCATTATTGGCCCGCTTCTTGCGCCGTAGCTTGCC
GCAAATGGTGGTGCTGTCTAACCTGGAAATTGGTGATAACCGCCAGATTCGTATGACCTCGACGATAGGATCCGCCTAA

Upstream 100 bases:

>100_bases
AGCGGGAAGGCGGGCTTATCCCGAAAAAACCTGAACATCTGCCGGTGCCGGAAGCACTGGATTTTGCAACAGAGAGTGAG
ACAAAGAGTGAGACAGACTA

Downstream 100 bases:

>100_bases
TGTTGATTCGGGCCTCCCACCGTGTATTGATTCTATTAGCGACCAGCCTGTTGCCGCTTAAGATTAACGCCGCATCCGGT
TCTTGGGTAGCGGATAATAT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
STLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
TYTLLTIGDGLVAQIPALVISTASGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAAL
LALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGY
LPPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIET
LAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQE
MLGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA

Sequences:

>Translated_692_residues
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
STLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
TYTLLTIGDGLVAQIPALVISTASGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAAL
LALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGY
LPPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIET
LAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQE
MLGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
>Mature_691_residues
ANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFS
TLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMP
GKQMAIDADLNAGLIGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAET
YTLLTIGDGLVAQIPALVISTASGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAALL
ALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYL
PPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFTV
VEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIETL
AEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEM
LGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=690, Percent_Identity=83.9130434782609, Blast_Score=1151, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74966; Mature: 74835

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFSTLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
HHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TYTLLTIGDGLVAQIPALVISTASGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLG
EEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHH
LLGMVPGMPNFVFLLFTAALLALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHCCCCCCEECEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYLPPVVHIRDNLELPPANYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEE
LMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
EEEECEECCCCCCCCCEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLMERVSIRDMRTIIETLAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEMLGAPPVLLVNHALRALLAR
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
HHHHCCCCEEHHCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
ANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFSTLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
HHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TYTLLTIGDGLVAQIPALVISTASGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLG
EEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHH
LLGMVPGMPNFVFLLFTAALLALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHCCCCCCEECEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYLPPVVHIRDNLELPPANYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEE
LMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
EEEECEECCCCCCCCCEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLMERVSIRDMRTIIETLAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEMLGAPPVLLVNHALRALLAR
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
HHHHCCCCEEHHCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387224 [H]