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The map label for this gene is ccmF [H]

Identifier: 108812369

GI number: 108812369

Start: 2494251

End: 2496221

Strand: Reverse

Name: ccmF [H]

Synonym: YPN_2208

Alternate gene names: 108812369

Gene position: 2496221-2494251 (Counterclockwise)

Preceding gene: 108812370

Following gene: 108812368

Centisome position: 55.05

GC content: 52.41

Gene sequence:

>1971_bases
ATGATCCCTGAAATTGGCAGTTTTTTATTATGTTTGGCGTTGGCGATTTCACTGCTGCTGAGTCTGTATCCACAATGGGG
AGCCGCGCGTCAGGATGCCCGTATGATGGCGGTTGGCAGGCCACTGACTTATGGCATGTTTGCCGCGATCACGTTGTCAT
TTATCTGTCTGATATATGCATTTGTGGTAAATGATTTTACCGTCTCCTATGTCGCGGCGAATTCCAACTCATATTTGCCG
ATTTATTACCGTATTGCCGCGAGTTGGGGAGCGCACGAAGGCTCCTTATTATTATGGGTATTGCTGCTCAGTTGTTGGTC
ATTGGCGGTAGCGCTGTTTAGCCGTTCGATGCCAGAGGATGCGGTGGCGCGGGTGTTATCCGTGCTGGGAATGATTACCG
GCGGTTTTCTGCTATTTATTATTCTGACGTCTAACCCGTTCTCTCGCACATTACCTGATTTTCCTATTGATGGCCGCGAT
CTGAACCCGCTACTACAAGATGTTGGGTTGATTTTCCATCCCCCGCTGCTCTACATGGGGTATGTCGGTTTCTCCGTCGC
GTTTGCTTTTGCAATTGCATCATTAATGGCCGGTAGGCTCGACAGTGCCTGGGCGCGTTGGTCACGTCCATGGACTCAGG
CCGCATGGATTTTCCTAACGCTTGGCATCGTACTTGGCTCAGCGTGGGCTTATTATGAATTGGGGTGGGGCGGCTGGTGG
TTCTGGGACCCGGTCGAAAATGCCTCCTTTATGCCGTGGCTGGCAGGTACCGCACTGATTCACTCACTGGCTGTCACGGA
GAAGCGCGGTACTTTCAAAGCGTGGACGGTATTGTTGGCGATCACCGCGTTCTCCTTGTGTTTGATGGGGACATTCTTAG
TCCGCTCAGGCGTGCTGGTTTCGGTGCACTCCTTTGCCTCTGATCCGGCCCGTGGCATGTTTATTCTGGCCTATCTGGTG
ATTGTGATTGGCGGTTCCCTGCTGCTGTATGCGGTAAAAGGCGCGCAGGTGCGCAGCCGGACTCAGCATGAAGTCTTTTC
CCGCGAGACTTTCCTGCTCGGCAACAATGTGTTGCTTATTGCCGCAATGCTCGTGGTGTTGCTGGGAACATTACTGCCAC
TGGTTCACAAACAGTTGGGATTGGGCAGTATCTCCATTGGTGAACCGTTCTTTAATACGATGTTCACTTGGTTAATGGCT
CCGATGGCATTGCTCATGGGGATAGGGCCGCTCGTGCGTTGGCGTCGTGATGAACCGAGCAAACTGTGGAAGCGGTTGAG
TGTGGCTCTGGTGGTCACTCTGCTGTTATCGATATCCGTACCGTGGCTGCTGCAAGATAGTGTCGCCGGTATGACGGTCG
TCGGGTTGATGATGGCCATTTGGGTGATCATCCTGACATTAATGGAATTGCACGAACGGGCCACCCATCGTTATGGCTTC
TGGCGTGGGTTGACTCACCTTTCCCGTAGCCACTGGGGCATGGTGTTGGGGCATCTCGGGGTGGCGGTTACGGTAATTGG
GATTGCGTTTAGCCAGAATTACAGTGTCGAACGCGATGTGCGCATGAAGGCCGGTGATAGTATCGATATCCATGATTATC
ACTTCACTTTTCGCGATGTCCACGATATCAAAGGGCCTAACTATACCGGCGGCGTTGGCATTATTGATGTCACCCGTAAT
GGTAAATTGGAGGCCACATTACATGCAGAAAAACGCTATTACAGTGTCGCCCGCTCAATGATGACTGAAGCAGCCATTGA
TGGGGGGCTGACCCGCGATCTTTATGCCGCCTTGGGTGAAGAGCTGGGCGATGGCTCATGGGCGGTCCGCTTGTATTACA
AACCTTTTGTGCGTTGGATATGGTTTGGCGGGATCTTTATGGCCGTCGGCGGCATCTTCTGTATGCTCGATCCGCGCTAT
CGGATGAGTAAAAAGCTAAAACGCGGTGCGATACCGGAGGCAGAGTCATGA

Upstream 100 bases:

>100_bases
ATGAAAAATACACGCCACCTGAAGTTGAAGAGGCAATGAAAGAGAACCACTCTCGCCCGGCGGCCGCTTATCGTGGCACT
AATACGACGGGTAATGCCTT

Downstream 100 bases:

>100_bases
AACCTCAATCCTCATTCAATAAGCTGATGTTTATTCCGCTGGTCCTTTTCTTACTGCTGGTCGTGGCATTCCTGATACAA
CTGACCCGTAATGCCAACGG

Product: cytochrome c-type biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MIPEIGSFLLCLALAISLLLSLYPQWGAARQDARMMAVGRPLTYGMFAAITLSFICLIYAFVVNDFTVSYVAANSNSYLP
IYYRIAASWGAHEGSLLLWVLLLSCWSLAVALFSRSMPEDAVARVLSVLGMITGGFLLFIILTSNPFSRTLPDFPIDGRD
LNPLLQDVGLIFHPPLLYMGYVGFSVAFAFAIASLMAGRLDSAWARWSRPWTQAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLAGTALIHSLAVTEKRGTFKAWTVLLAITAFSLCLMGTFLVRSGVLVSVHSFASDPARGMFILAYLV
IVIGGSLLLYAVKGAQVRSRTQHEVFSRETFLLGNNVLLIAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMA
PMALLMGIGPLVRWRRDEPSKLWKRLSVALVVTLLLSISVPWLLQDSVAGMTVVGLMMAIWVIILTLMELHERATHRYGF
WRGLTHLSRSHWGMVLGHLGVAVTVIGIAFSQNYSVERDVRMKAGDSIDIHDYHFTFRDVHDIKGPNYTGGVGIIDVTRN
GKLEATLHAEKRYYSVARSMMTEAAIDGGLTRDLYAALGEELGDGSWAVRLYYKPFVRWIWFGGIFMAVGGIFCMLDPRY
RMSKKLKRGAIPEAES

Sequences:

>Translated_656_residues
MIPEIGSFLLCLALAISLLLSLYPQWGAARQDARMMAVGRPLTYGMFAAITLSFICLIYAFVVNDFTVSYVAANSNSYLP
IYYRIAASWGAHEGSLLLWVLLLSCWSLAVALFSRSMPEDAVARVLSVLGMITGGFLLFIILTSNPFSRTLPDFPIDGRD
LNPLLQDVGLIFHPPLLYMGYVGFSVAFAFAIASLMAGRLDSAWARWSRPWTQAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLAGTALIHSLAVTEKRGTFKAWTVLLAITAFSLCLMGTFLVRSGVLVSVHSFASDPARGMFILAYLV
IVIGGSLLLYAVKGAQVRSRTQHEVFSRETFLLGNNVLLIAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMA
PMALLMGIGPLVRWRRDEPSKLWKRLSVALVVTLLLSISVPWLLQDSVAGMTVVGLMMAIWVIILTLMELHERATHRYGF
WRGLTHLSRSHWGMVLGHLGVAVTVIGIAFSQNYSVERDVRMKAGDSIDIHDYHFTFRDVHDIKGPNYTGGVGIIDVTRN
GKLEATLHAEKRYYSVARSMMTEAAIDGGLTRDLYAALGEELGDGSWAVRLYYKPFVRWIWFGGIFMAVGGIFCMLDPRY
RMSKKLKRGAIPEAES
>Mature_656_residues
MIPEIGSFLLCLALAISLLLSLYPQWGAARQDARMMAVGRPLTYGMFAAITLSFICLIYAFVVNDFTVSYVAANSNSYLP
IYYRIAASWGAHEGSLLLWVLLLSCWSLAVALFSRSMPEDAVARVLSVLGMITGGFLLFIILTSNPFSRTLPDFPIDGRD
LNPLLQDVGLIFHPPLLYMGYVGFSVAFAFAIASLMAGRLDSAWARWSRPWTQAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLAGTALIHSLAVTEKRGTFKAWTVLLAITAFSLCLMGTFLVRSGVLVSVHSFASDPARGMFILAYLV
IVIGGSLLLYAVKGAQVRSRTQHEVFSRETFLLGNNVLLIAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMA
PMALLMGIGPLVRWRRDEPSKLWKRLSVALVVTLLLSISVPWLLQDSVAGMTVVGLMMAIWVIILTLMELHERATHRYGF
WRGLTHLSRSHWGMVLGHLGVAVTVIGIAFSQNYSVERDVRMKAGDSIDIHDYHFTFRDVHDIKGPNYTGGVGIIDVTRN
GKLEATLHAEKRYYSVARSMMTEAAIDGGLTRDLYAALGEELGDGSWAVRLYYKPFVRWIWFGGIFMAVGGIFCMLDPRY
RMSKKLKRGAIPEAES

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=654, Percent_Identity=71.1009174311927, Blast_Score=915, Evalue=0.0,
Organism=Escherichia coli, GI1790511, Length=336, Percent_Identity=49.702380952381, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 72866; Mature: 72866

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPEIGSFLLCLALAISLLLSLYPQWGAARQDARMMAVGRPLTYGMFAAITLSFICLIYA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
FVVNDFTVSYVAANSNSYLPIYYRIAASWGAHEGSLLLWVLLLSCWSLAVALFSRSMPED
HHHHCCEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AVARVLSVLGMITGGFLLFIILTSNPFSRTLPDFPIDGRDLNPLLQDVGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCHHHHCCHHHHHH
YVGFSVAFAFAIASLMAGRLDSAWARWSRPWTQAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLAGTALIHSLAVTEKRGTFKAWTVLLAITAFSLCLMGTFLVRSGVLV
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
SVHSFASDPARGMFILAYLVIVIGGSLLLYAVKGAQVRSRTQHEVFSRETFLLGNNVLLI
EEHHHCCCCCHHHHHHHHHHHHHCCHHHHHEECCHHHHHHHHHHHHHCCCEEECCCHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMAPMALLMGIGPLVRWRRDEPS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KLWKRLSVALVVTLLLSISVPWLLQDSVAGMTVVGLMMAIWVIILTLMELHERATHRYGF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRGLTHLSRSHWGMVLGHLGVAVTVIGIAFSQNYSVERDVRMKAGDSIDIHDYHFTFRDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEEEEEHHHH
HDIKGPNYTGGVGIIDVTRNGKLEATLHAEKRYYSVARSMMTEAAIDGGLTRDLYAALGE
HHCCCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ELGDGSWAVRLYYKPFVRWIWFGGIFMAVGGIFCMLDPRYRMSKKLKRGAIPEAES
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIPEIGSFLLCLALAISLLLSLYPQWGAARQDARMMAVGRPLTYGMFAAITLSFICLIYA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
FVVNDFTVSYVAANSNSYLPIYYRIAASWGAHEGSLLLWVLLLSCWSLAVALFSRSMPED
HHHHCCEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AVARVLSVLGMITGGFLLFIILTSNPFSRTLPDFPIDGRDLNPLLQDVGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCHHHHCCHHHHHH
YVGFSVAFAFAIASLMAGRLDSAWARWSRPWTQAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLAGTALIHSLAVTEKRGTFKAWTVLLAITAFSLCLMGTFLVRSGVLV
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
SVHSFASDPARGMFILAYLVIVIGGSLLLYAVKGAQVRSRTQHEVFSRETFLLGNNVLLI
EEHHHCCCCCHHHHHHHHHHHHHCCHHHHHEECCHHHHHHHHHHHHHCCCEEECCCHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMAPMALLMGIGPLVRWRRDEPS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KLWKRLSVALVVTLLLSISVPWLLQDSVAGMTVVGLMMAIWVIILTLMELHERATHRYGF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRGLTHLSRSHWGMVLGHLGVAVTVIGIAFSQNYSVERDVRMKAGDSIDIHDYHFTFRDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEEEEEHHHH
HDIKGPNYTGGVGIIDVTRNGKLEATLHAEKRYYSVARSMMTEAAIDGGLTRDLYAALGE
HHCCCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ELGDGSWAVRLYYKPFVRWIWFGGIFMAVGGIFCMLDPRYRMSKKLKRGAIPEAES
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]