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The map label for this gene is nuoA

Identifier: 108812312

GI number: 108812312

Start: 2431657

End: 2432157

Strand: Reverse

Name: nuoA

Synonym: YPN_2150

Alternate gene names: 108812312

Gene position: 2432157-2431657 (Counterclockwise)

Preceding gene: 108812313

Following gene: 108812311

Centisome position: 53.64

GC content: 49.9

Gene sequence:

>501_bases
ATGCGTATGTCAACAACCACTGAAATTATCGCTCATCACTGGGCGTTCGCTGTATTCCTCATCGGCGCTGTTGGGCTGTG
CGGTTTGATGCTTTTAGGTGCGTACTTCCTCGGGGGGAGAGCCCAGGCTCGTGCCAAAAACGTGCCTTATGAATCAGGTA
TAGATTCAGTAGGCTCTGCGCGTATGCGCCTGTCCGCCAAGTTTTATCTGGTTGCGATGTTTTTCGTTATTTTCGATGTT
GAAGCCCTCTACCTTTATGCCTGGTCAATCTCCATTCGTGAGAGTGGCTGGATAGGCTTTATCGAAGCAGCCATTTTCAT
TTTGGTGCTCTTGGCTGGTTTGTTTTATCTGGTGCGCATTGGTGCCCTGGATTGGACTCCTACACGTTCTAATCGTCGTG
TGAGCAAACCCAGTACCGTGAGATACGCCAGCAGTCATCCGCAAGATATATCCCAAGAGCTTAGCGTTGCAGGTAGCCAG
CAAGCGAACGAATCCCGATAA

Upstream 100 bases:

>100_bases
GTGTTAAGTGTGGTTTTTAATCCTTCCCTTTGAATCGATGTGGTGCACTAACTGCCAATACAAGAGCAGCATGTCCGACG
CCACTTTTGATGAGTAAGCA

Downstream 100 bases:

>100_bases
GCTGATATCAGTCAGTGATTCGGGTCAGTGAACCTAGCTAACAGCCCAGCAGCGTCAAGTGCAAAAGGTATAGTGGTCAA
TAAATATAGCGAGGCATTAA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MRMSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDV
EALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQ
QANESR

Sequences:

>Translated_166_residues
MRMSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDV
EALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQ
QANESR
>Mature_166_residues
MRMSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDV
EALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQ
QANESR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=139, Percent_Identity=80.5755395683453, Blast_Score=235, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_YERP3 (A7FGQ5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400433.1
- STRING:   A7FGQ5
- GeneID:   5387299
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1454
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- ProtClustDB:   PRK06602
- BioCyc:   YPSE349747:YPSIP31758_1454-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 18377; Mature: 18377

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11986a64)-; HASH(0x10f05554)-; HASH(0x10dc3d6c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHH
RMRLSAKFYLVAMFFVIFDVEALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQANESR
CCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MRMSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHH
RMRLSAKFYLVAMFFVIFDVEALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQANESR
CCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA