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The map label for this gene is idnR [H]

Identifier: 108812294

GI number: 108812294

Start: 2409700

End: 2410692

Strand: Reverse

Name: idnR [H]

Synonym: YPN_2132

Alternate gene names: 108812294

Gene position: 2410692-2409700 (Counterclockwise)

Preceding gene: 108812299

Following gene: 108812293

Centisome position: 53.16

GC content: 47.03

Gene sequence:

>993_bases
ATGAAAAACCAGCGAGTTACGTTACAGGATATCGCGTTACTGGCGGGCGTGACTAAAATGACAGTCAGCCGCTATTTACG
GATGCCGGAAAAAGTGGCACCAGAAACCGGTGAGCGCATTGCTCAGGTGATGGCTGAAGTGAATTACAGTGCGGATCCCG
AAAGTGAAACCAGCCTAAATCAGAAAAGTCCGCGTATTGGTATTTTGGTCCCCTCGTTTAATAACCAAATCTTCTCCGAT
CTGCTGGCAGGGATTGAATCAATCACCGTTGCCAATGGCTATCAGACGTTGGTGGTTAACTATAACTACAATAAAGCGCG
GGAAGAGGAGCAGATTATTAACCTGCTCTCCTGTCAGATATCCGGCTTGATCCTCACAGATTCCGAACATACCTTACGCG
CAGATAAATATTTGAATGCAGCAGAGATTCCGATTGCACAAGTGATGGAGCTGGAGCCGCAAGAGAATCGAATAACCGTT
GGTTTTAATAACTATCAAGCGGCTTACGACATGACGACCACGCTGTTGGCTAGCGGCAAGCAACATATTGTTTATTTTGG
CTCAATGTCAGATGCGCGTGATCGTAAGCGTTATCAGGGCTATAGCCAGGCGGTGACTGATGCAGGCTTCACACCGCTGC
ACATTACCCCAAATAAAGTGTCCTCCGTCTCTATTGGCGCAGGGATGCTGGCATTGGCGAGGCAAATGTATCCCGATGTC
GATGCTATTTTTTGTACTAATGATGATATGGCTGTCGGAGTGTTACAAGAATGTCTGAAACTGGGGGTGGCAATACCGGC
TGAAATGGCGATTTCCGGTTTCCATGGGTTGGATATCGGTCAGGCGACAACACCAATATTAGCCAGTGTGACCACACCGC
GTTTTGAAATGGGGAAAGTTGCCGCCGAAATTTTGATTAAGAAAATCAAAAAAATCCCGACTATTGAACAGGTTGACCTG
CATTATCGTATCTCTCTCGGTGGGACTATCTGA

Upstream 100 bases:

>100_bases
GATCTACGCGCTGAGGTTATGCATTAATAGCATTAACATTTCGATCAACCTGGGCCATAATCAACCCACTTTTTTCGCAC
TTTAGTACCAGGTATTTGCC

Downstream 100 bases:

>100_bases
GACTAAAGGGAAGTCGATTCGGTTTCCTGTTATTTTTCATCACCACGGCCCTGTGCATTGGCAATGCACGCGGGTAGAGC
ATCGGCTCATCAATTATCGC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRMPEKVAPETGERIAQVMAEVNYSADPESETSLNQKSPRIGILVPSFNNQIFSD
LLAGIESITVANGYQTLVVNYNYNKAREEEQIINLLSCQISGLILTDSEHTLRADKYLNAAEIPIAQVMELEPQENRITV
GFNNYQAAYDMTTTLLASGKQHIVYFGSMSDARDRKRYQGYSQAVTDAGFTPLHITPNKVSSVSIGAGMLALARQMYPDV
DAIFCTNDDMAVGVLQECLKLGVAIPAEMAISGFHGLDIGQATTPILASVTTPRFEMGKVAAEILIKKIKKIPTIEQVDL
HYRISLGGTI

Sequences:

>Translated_330_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRMPEKVAPETGERIAQVMAEVNYSADPESETSLNQKSPRIGILVPSFNNQIFSD
LLAGIESITVANGYQTLVVNYNYNKAREEEQIINLLSCQISGLILTDSEHTLRADKYLNAAEIPIAQVMELEPQENRITV
GFNNYQAAYDMTTTLLASGKQHIVYFGSMSDARDRKRYQGYSQAVTDAGFTPLHITPNKVSSVSIGAGMLALARQMYPDV
DAIFCTNDDMAVGVLQECLKLGVAIPAEMAISGFHGLDIGQATTPILASVTTPRFEMGKVAAEILIKKIKKIPTIEQVDL
HYRISLGGTI
>Mature_330_residues
MKNQRVTLQDIALLAGVTKMTVSRYLRMPEKVAPETGERIAQVMAEVNYSADPESETSLNQKSPRIGILVPSFNNQIFSD
LLAGIESITVANGYQTLVVNYNYNKAREEEQIINLLSCQISGLILTDSEHTLRADKYLNAAEIPIAQVMELEPQENRITV
GFNNYQAAYDMTTTLLASGKQHIVYFGSMSDARDRKRYQGYSQAVTDAGFTPLHITPNKVSSVSIGAGMLALARQMYPDV
DAIFCTNDDMAVGVLQECLKLGVAIPAEMAISGFHGLDIGQATTPILASVTTPRFEMGKVAAEILIKKIKKIPTIEQVDL
HYRISLGGTI

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=49.0963855421687, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=44.4108761329305, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=28.3870967741935, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790194, Length=321, Percent_Identity=24.9221183800623, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788474, Length=325, Percent_Identity=28, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=25, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789202, Length=312, Percent_Identity=24.6794871794872, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=24.812030075188, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787580, Length=349, Percent_Identity=23.7822349570201, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786540, Length=309, Percent_Identity=23.9482200647249, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36195; Mature: 36195

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQRVTLQDIALLAGVTKMTVSRYLRMPEKVAPETGERIAQVMAEVNYSADPESETSLN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCC
QKSPRIGILVPSFNNQIFSDLLAGIESITVANGYQTLVVNYNYNKAREEEQIINLLSCQI
CCCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHC
SGLILTDSEHTLRADKYLNAAEIPIAQVMELEPQENRITVGFNNYQAAYDMTTTLLASGK
CCEEEECCCCHHHHHHCCCHHCCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
QHIVYFGSMSDARDRKRYQGYSQAVTDAGFTPLHITPNKVSSVSIGAGMLALARQMYPDV
CEEEEEECCCCHHHHHHHCCHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHCCCC
DAIFCTNDDMAVGVLQECLKLGVAIPAEMAISGFHGLDIGQATTPILASVTTPRFEMGKV
CEEEECCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHHEECCCCCHHHHHH
AAEILIKKIKKIPTIEQVDLHYRISLGGTI
HHHHHHHHHHHCCCEEEECEEEEEECCCCC
>Mature Secondary Structure
MKNQRVTLQDIALLAGVTKMTVSRYLRMPEKVAPETGERIAQVMAEVNYSADPESETSLN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCC
QKSPRIGILVPSFNNQIFSDLLAGIESITVANGYQTLVVNYNYNKAREEEQIINLLSCQI
CCCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHC
SGLILTDSEHTLRADKYLNAAEIPIAQVMELEPQENRITVGFNNYQAAYDMTTTLLASGK
CCEEEECCCCHHHHHHCCCHHCCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
QHIVYFGSMSDARDRKRYQGYSQAVTDAGFTPLHITPNKVSSVSIGAGMLALARQMYPDV
CEEEEEECCCCHHHHHHHCCHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHCCCC
DAIFCTNDDMAVGVLQECLKLGVAIPAEMAISGFHGLDIGQATTPILASVTTPRFEMGKV
CEEEECCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHHEECCCCCHHHHHH
AAEILIKKIKKIPTIEQVDLHYRISLGGTI
HHHHHHHHHHHCCCEEEECEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]