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The map label for this gene is rbsC [H]

Identifier: 108812255

GI number: 108812255

Start: 2370076

End: 2371068

Strand: Reverse

Name: rbsC [H]

Synonym: YPN_2093

Alternate gene names: 108812255

Gene position: 2371068-2370076 (Counterclockwise)

Preceding gene: 108812256

Following gene: 108812252

Centisome position: 52.29

GC content: 51.76

Gene sequence:

>993_bases
ATGATCAGAACTGAACACTCTTCTTCTACGCAAGAGAGCGGTAGCACTCTCCATCGCCATAAACGTTGGGAGAAATTATT
ACATCACCCGGCCATGTTGCCATTTATTGGTTTTGTTGTGCTATTTGTCTTAATGAGCGGGTTAAATGACAGTTTTTTGA
CCGTAAATAACCTCACTAACGTGGCGCGGCAGGTGTCGATTAATGCCATTATCGCGGTAGGCATGACTTGCGCGATCTTG
ACCGGGGGGATCGATCTTTCGGTTGGGCCAGTCATGGCGTTGTCAGGGTCTATTGCTGCCGGGCTGATGCTGGCCGGTAT
TCCTATTCCGTTAGCCATGATGGCCGCTCTGTTAGTCGGTGCCTTATTTGGCCTGGCGAATGGGAGTTGTATTGCTTATC
TGCGGATGCCGCCTATCATCGTGACGCTGGCCTCTATGGGGATCGCCCGTGGTTTGGCGTTGTTGTACACCGGGGGGTAC
CCCATCTCCGGTTTACCTGACATGTTTTCATTCTTTGGCCGAGGTACGGTACTGGGTATTCAAGTCCCCATTCTGATCAT
GGCCGGTGTTTATCTGTTCGCTTGGATCATGCTCAACCATTTATCGTTTGGTCGCTATATTTATGCTATCGGTGGCAACG
AAGAAGCGGCGCGTTTGAGTGGTATCCGTGTGTCGCGCTATAAAATGCTGGTATATGTGGTCAGTGGCCTGACAGCCGCG
TTGGCCGGGCTGGTACTGACTTCGCGGCTAATGAGTGGGCAACCTAATGCGGGCGAAGGGTTTGAACTGGACGCTATCGC
CGCCGTTGTTTTGGGCGGTGCGGCAATCTCCGGAGGCAAGGGGGCGATTATTGGTACGTTGGTAGGGGCGATGATGTTGG
GGGTGTTGAATAATGGTCTCAACCTGATGAGCGTATCGCCTTATATCCAGAATGTCGTGAAAGGCGGCATTATTCTTGCG
GCGATCTATCTCAGTTCCGTTCGGCGCAAATAA

Upstream 100 bases:

>100_bases
ATCGCGTCCTGGTTTTCCGTGGTGGGCACATTGTTGCCGAACTGGCGGGTGATGAAATTGAATCTAATAACATCATGCTT
CACGCAACAGGGAGTGCATT

Downstream 100 bases:

>100_bases
GCGGTGATGAATTTGATACAGTGATAAATTTGATACAGTAATTAAGTTGATGCAGTGAGGGTAATGGCGGCGCGATAATG
GCCGCCATTACGGCGGGTTG

Product: sugar transport system, permease protein

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIRTEHSSSTQESGSTLHRHKRWEKLLHHPAMLPFIGFVVLFVLMSGLNDSFLTVNNLTNVARQVSINAIIAVGMTCAIL
TGGIDLSVGPVMALSGSIAAGLMLAGIPIPLAMMAALLVGALFGLANGSCIAYLRMPPIIVTLASMGIARGLALLYTGGY
PISGLPDMFSFFGRGTVLGIQVPILIMAGVYLFAWIMLNHLSFGRYIYAIGGNEEAARLSGIRVSRYKMLVYVVSGLTAA
LAGLVLTSRLMSGQPNAGEGFELDAIAAVVLGGAAISGGKGAIIGTLVGAMMLGVLNNGLNLMSVSPYIQNVVKGGIILA
AIYLSSVRRK

Sequences:

>Translated_330_residues
MIRTEHSSSTQESGSTLHRHKRWEKLLHHPAMLPFIGFVVLFVLMSGLNDSFLTVNNLTNVARQVSINAIIAVGMTCAIL
TGGIDLSVGPVMALSGSIAAGLMLAGIPIPLAMMAALLVGALFGLANGSCIAYLRMPPIIVTLASMGIARGLALLYTGGY
PISGLPDMFSFFGRGTVLGIQVPILIMAGVYLFAWIMLNHLSFGRYIYAIGGNEEAARLSGIRVSRYKMLVYVVSGLTAA
LAGLVLTSRLMSGQPNAGEGFELDAIAAVVLGGAAISGGKGAIIGTLVGAMMLGVLNNGLNLMSVSPYIQNVVKGGIILA
AIYLSSVRRK
>Mature_330_residues
MIRTEHSSSTQESGSTLHRHKRWEKLLHHPAMLPFIGFVVLFVLMSGLNDSFLTVNNLTNVARQVSINAIIAVGMTCAIL
TGGIDLSVGPVMALSGSIAAGLMLAGIPIPLAMMAALLVGALFGLANGSCIAYLRMPPIIVTLASMGIARGLALLYTGGY
PISGLPDMFSFFGRGTVLGIQVPILIMAGVYLFAWIMLNHLSFGRYIYAIGGNEEAARLSGIRVSRYKMLVYVVSGLTAA
LAGLVLTSRLMSGQPNAGEGFELDAIAAVVLGGAAISGGKGAIIGTLVGAMMLGVLNNGLNLMSVSPYIQNVVKGGIILA
AIYLSSVRRK

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=325, Percent_Identity=47.0769230769231, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI1790524, Length=282, Percent_Identity=41.4893617021277, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI145693152, Length=326, Percent_Identity=37.7300613496933, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789992, Length=344, Percent_Identity=35.7558139534884, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1788896, Length=284, Percent_Identity=36.9718309859155, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788471, Length=320, Percent_Identity=39.0625, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI145693214, Length=245, Percent_Identity=38.3673469387755, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787793, Length=276, Percent_Identity=36.231884057971, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787794, Length=296, Percent_Identity=34.7972972972973, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082395, Length=261, Percent_Identity=36.0153256704981, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34452; Mature: 34452

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTEHSSSTQESGSTLHRHKRWEKLLHHPAMLPFIGFVVLFVLMSGLNDSFLTVNNLTN
CCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
VARQVSINAIIAVGMTCAILTGGIDLSVGPVMALSGSIAAGLMLAGIPIPLAMMAALLVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
ALFGLANGSCIAYLRMPPIIVTLASMGIARGLALLYTGGYPISGLPDMFSFFGRGTVLGI
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEEEH
QVPILIMAGVYLFAWIMLNHLSFGRYIYAIGGNEEAARLSGIRVSRYKMLVYVVSGLTAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LAGLVLTSRLMSGQPNAGEGFELDAIAAVVLGGAAISGGKGAIIGTLVGAMMLGVLNNGL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCC
NLMSVSPYIQNVVKGGIILAAIYLSSVRRK
CEEEECHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRTEHSSSTQESGSTLHRHKRWEKLLHHPAMLPFIGFVVLFVLMSGLNDSFLTVNNLTN
CCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
VARQVSINAIIAVGMTCAILTGGIDLSVGPVMALSGSIAAGLMLAGIPIPLAMMAALLVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
ALFGLANGSCIAYLRMPPIIVTLASMGIARGLALLYTGGYPISGLPDMFSFFGRGTVLGI
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEEEH
QVPILIMAGVYLFAWIMLNHLSFGRYIYAIGGNEEAARLSGIRVSRYKMLVYVVSGLTAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LAGLVLTSRLMSGQPNAGEGFELDAIAAVVLGGAAISGGKGAIIGTLVGAMMLGVLNNGL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCC
NLMSVSPYIQNVVKGGIILAAIYLSSVRRK
CEEEECHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]