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The map label for this gene is thiK [H]

Identifier: 108812177

GI number: 108812177

Start: 2279402

End: 2280268

Strand: Reverse

Name: thiK [H]

Synonym: YPN_2015

Alternate gene names: 108812177

Gene position: 2280268-2279402 (Counterclockwise)

Preceding gene: 108812178

Following gene: 108812176

Centisome position: 50.29

GC content: 49.83

Gene sequence:

>867_bases
ATGCGCCTGTCCAATATTGATTCTTCTCTGTCTGCCTTAATAGCAAACATCAATCCGGCGGTGAAAACCGCCGATTGTCA
TATTAGCCCGGTATCAGGATTAACCGGTGAAAGTTGGCGTATTACTGGCCCAGGGATTGACTGGCTGGCGCGTGAGCAAT
CGCCGCACAAAAGTCAGTTGGGGGTCAACCGACGACGTGAGCGTAAATTCCTGCAACATATTGCTGGCAATGGGCTGTCT
CCAGCGGTGATTGCTGCTAATCAGCGTTGGCTAGTGGTGAACTGGCTTGAAGGTGACGTTGTCACTAATGAGCAGTTCAT
CCCATTGGTGAATCATGGGCAATTAGCGCGGTTACTGGCCCGCTTGCATCATTTGCCCGCGAGTGGTTACCGTCTGGATT
TGCGTGCTCAGATTGCCCGCTATGGGGCGCTTATTGATCCTACGCGCCGTTCACCTGGCGGAGTGCGGCTACAGCATGAT
TTTCTTCGTAGGCCATTACCAGCGATAACAAAAATTGCTCCTTTGCATATGGATATTCACCCCGGCAATTTGTTAACAAC
CCCCGTTGGGCTGAAATTAATTGACTGGGAATATGCGGCAGATGGCGATATTGCTTTGGAAATTGCCGCGCTATTTCGCG
GTAATCATTGGTCAATGCTACAACAACAGGCTTTTTTGCAGGACTATTGCAACAATGAGCACGGTTATCATGACATCGCT
CGTTTATCCCGTCAGATTCAGCAATGGTTGCCCTGGGTCGATTACCTGATGTTGATGTGGTTTGAAGTGCGTTGGCAGCA
AACCGCGGACCCAATATTCTTGGCATGGGCCGCGCCGTTGCGCCAACGTTTTAATTTGTCTTTTTAA

Upstream 100 bases:

>100_bases
CAATATGTGCTGTACAGTGATGTCAGTGGCGATGTGAAATCTCCGACCATTGAAATGCAATTGATGCAGACACAAACCGG
TGAAATCATTTGGTCTGGTA

Downstream 100 bases:

>100_bases
GCCCTGCGGCACCAAGCCCGCCGCTTCAAGCACGAAGGGTCGTTATCAATCTGAATAAAGTGAGGTGACCGTGGGTCCCG
TGATGTTAGATGTTGCCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MRLSNIDSSLSALIANINPAVKTADCHISPVSGLTGESWRITGPGIDWLAREQSPHKSQLGVNRRRERKFLQHIAGNGLS
PAVIAANQRWLVVNWLEGDVVTNEQFIPLVNHGQLARLLARLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHD
FLRRPLPAITKIAPLHMDIHPGNLLTTPVGLKLIDWEYAADGDIALEIAALFRGNHWSMLQQQAFLQDYCNNEHGYHDIA
RLSRQIQQWLPWVDYLMLMWFEVRWQQTADPIFLAWAAPLRQRFNLSF

Sequences:

>Translated_288_residues
MRLSNIDSSLSALIANINPAVKTADCHISPVSGLTGESWRITGPGIDWLAREQSPHKSQLGVNRRRERKFLQHIAGNGLS
PAVIAANQRWLVVNWLEGDVVTNEQFIPLVNHGQLARLLARLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHD
FLRRPLPAITKIAPLHMDIHPGNLLTTPVGLKLIDWEYAADGDIALEIAALFRGNHWSMLQQQAFLQDYCNNEHGYHDIA
RLSRQIQQWLPWVDYLMLMWFEVRWQQTADPIFLAWAAPLRQRFNLSF
>Mature_288_residues
MRLSNIDSSLSALIANINPAVKTADCHISPVSGLTGESWRITGPGIDWLAREQSPHKSQLGVNRRRERKFLQHIAGNGLS
PAVIAANQRWLVVNWLEGDVVTNEQFIPLVNHGQLARLLARLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHD
FLRRPLPAITKIAPLHMDIHPGNLLTTPVGLKLIDWEYAADGDIALEIAALFRGNHWSMLQQQAFLQDYCNNEHGYHDIA
RLSRQIQQWLPWVDYLMLMWFEVRWQQTADPIFLAWAAPLRQRFNLSF

Specific function: Catalyzes the phosphorylation of thiamine to thiamine phosphate [H]

COG id: COG0510

COG function: function code M; Predicted choline kinase involved in LPS biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787349, Length=248, Percent_Identity=37.5, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR011009
- InterPro:   IPR014093 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.89 [H]

Molecular weight: Translated: 32796; Mature: 32796

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSNIDSSLSALIANINPAVKTADCHISPVSGLTGESWRITGPGIDWLAREQSPHKSQL
CCCCCHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCEEEECCCCHHHHCCCCCCHHHH
GVNRRRERKFLQHIAGNGLSPAVIAANQRWLVVNWLEGDVVTNEQFIPLVNHGQLARLLA
CCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCEECCCCEEEEECCCHHHHHHH
RLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHDFLRRPLPAITKIAPLHMDIH
HHHCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHCCCEEEEEC
PGNLLTTPVGLKLIDWEYAADGDIALEIAALFRGNHWSMLQQQAFLQDYCNNEHGYHDIA
CCCEEECCCCEEEEEEEECCCCCHHEEEEEHHCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RLSRQIQQWLPWVDYLMLMWFEVRWQQTADPIFLAWAAPLRQRFNLSF
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCC
>Mature Secondary Structure
MRLSNIDSSLSALIANINPAVKTADCHISPVSGLTGESWRITGPGIDWLAREQSPHKSQL
CCCCCHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCEEEECCCCHHHHCCCCCCHHHH
GVNRRRERKFLQHIAGNGLSPAVIAANQRWLVVNWLEGDVVTNEQFIPLVNHGQLARLLA
CCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCEECCCCEEEEECCCHHHHHHH
RLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHDFLRRPLPAITKIAPLHMDIH
HHHCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHCCCEEEEEC
PGNLLTTPVGLKLIDWEYAADGDIALEIAALFRGNHWSMLQQQAFLQDYCNNEHGYHDIA
CCCEEECCCCEEEEEEEECCCCCHHEEEEEHHCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RLSRQIQQWLPWVDYLMLMWFEVRWQQTADPIFLAWAAPLRQRFNLSF
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA