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The map label for this gene is intA [H]

Identifier: 108811289

GI number: 108811289

Start: 1294646

End: 1295128

Strand: Reverse

Name: intA [H]

Synonym: YPN_1126

Alternate gene names: 108811289

Gene position: 1295128-1294646 (Counterclockwise)

Preceding gene: 108811290

Following gene: 108811288

Centisome position: 28.56

GC content: 46.79

Gene sequence:

>483_bases
TTGGGCCGTTGGTGGAGATATAAGTGGATCACTTTTCATCCGTCGTTGACATTAGTCAAAACTACCGGCAAGAAAATTTG
GCGTTTCCACTATCAGCTTCCCAACAGTAGTAAACGCACTATGGTAAGCCTTGGCGCGTACCCTGCACTTTCTTTGGCTG
ATGCCAGAGAAGTACGAGCCGAGAAACTGGCCATGTTAGTGCGAGGGGTTGATCCCCAAGCAAGAGCTGATGAAGAAGCT
GAAAAGCTCCAGATAGCGGAGGAAAGCATTTTTGTGAATGTCGCCCGTAAATGGTTCGAGTTGAAAGAAAGCCACGTTAG
CGCAGCCCATGCGAAAGATATTTGGCGTTCTATTGAAAAAGACATCTTACCCAGCATCGAAAGTGTTCCCATCCAAGAAT
TAAAAGCACGTACCCTGATTCAGGTATTAGAACCCATCAAAGCACGGGGAGCATTAGAGACTGACCTGCTCCCCATTGAA
TAA

Upstream 100 bases:

>100_bases
ACATGTCGTTCAAATCAAAGGAGAAAGCTATCGACTCAGACAGAAACGAAAGGCCGGGGTTATAGCAGAAGCTAATCCTG
AGTAAAACGGTGGATCAATA

Downstream 100 bases:

>100_bases
CACACTCCGATGTTAGTAATGTCTTCATCAGCAACATGAGGACACCCCATGAAGAAACGTTTTTCCGACGAACAGATCAT
CAATATTCTCCGCGAGGCTG

Product: phage family integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MGRWWRYKWITFHPSLTLVKTTGKKIWRFHYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLAMLVRGVDPQARADEEA
EKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIESVPIQELKARTLIQVLEPIKARGALETDLLPIE

Sequences:

>Translated_160_residues
MGRWWRYKWITFHPSLTLVKTTGKKIWRFHYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLAMLVRGVDPQARADEEA
EKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIESVPIQELKARTLIQVLEPIKARGALETDLLPIE
>Mature_159_residues
GRWWRYKWITFHPSLTLVKTTGKKIWRFHYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLAMLVRGVDPQARADEEAE
KLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIESVPIQELKARTLIQVLEPIKARGALETDLLPIE

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=137, Percent_Identity=45.2554744525547, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI145693166, Length=129, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788690, Length=147, Percent_Identity=26.530612244898, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 18402; Mature: 18270

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRWWRYKWITFHPSLTLVKTTGKKIWRFHYQLPNSSKRTMVSLGAYPALSLADAREVRA
CCCEEEEEEEEECCCEEEEEECCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
EKLAMLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEK
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILPSIESVPIQELKARTLIQVLEPIKARGALETDLLPIE
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GRWWRYKWITFHPSLTLVKTTGKKIWRFHYQLPNSSKRTMVSLGAYPALSLADAREVRA
CCEEEEEEEEECCCEEEEEECCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
EKLAMLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEK
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILPSIESVPIQELKARTLIQVLEPIKARGALETDLLPIE
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]