Click here to switch to the map view.

The map label for this gene is nagC [H]

Identifier: 108811274

GI number: 108811274

Start: 1276005

End: 1277270

Strand: Reverse

Name: nagC [H]

Synonym: YPN_1111

Alternate gene names: 108811274

Gene position: 1277270-1276005 (Counterclockwise)

Preceding gene: 108811275

Following gene: 108811273

Centisome position: 28.17

GC content: 49.68

Gene sequence:

>1266_bases
ATGGCAACGAGGTTTTATCATAAGCGAGTAACTTTATTGATGAGCACCGGCGGACAAGCACAAATTGGTAACGTGGATCT
GGTAAAACAACTCAATGGAGCCGTGGTTTACCGGCTAATTGATCAGCAAGGCCCGATTTCTCGCATACAGATTGCCGATC
TCAGCCAGCTAGCCCCCGCCAGTGTCACCAAAATCACCCGGCAATTGTTGGAGCGCGGGCTGATCAAAGAGGTCGATCAG
CAAGCCTCCACCGGGGGGCGTCGCGCTATCTCTATCGTGACGGAAAACCGCCAATTCCATACCGTTGCAGTCCGTTTAGG
TCGTAATGATGCCACGATCACCCTCTTTGACATGAGCGGTAAATCGCTGGGTGAAGAGCACTATGCCCTGCCAGAACGAA
CACAAGAAACGCTGGAACACGCCTTATTTAATATCATCAGTCAGTTTATTGACGCCTATCAGCGTAAATTACGTGAACTG
ATTGCCATCGCGGTTATCCTGCCTGGGCTGGTTGAGCAAAGCAAAGGTATCGTGCGCTATATGCCGCATATCAGTGTCAG
TAACTGGCCGTTAGTCGATAATCTACAAGCGCGCTTTAACGTCACCAGTTTTGTGGGTCACGATATCCGCAGCCTGGCAC
TGGCCGAGCACTATTTTGGTGCAACCCGTGACTGTGAAGACTCCATTTTGGTTCGTCTACATCGAGGCACGGGTGCCGGT
ATTATCGTTAACAGCCAAATATTTTTAGGCAGCAACGGCAACGTTGGCGAGATAGGCCATATTCAGATTGATCCATTAGG
TGATCGCTGCTATTGCGGTAACTTTGGTTGTCTGGAAACCGTGGCATCCAACGCCGCGATTGAAAACCGCGTCAAGCACC
TTCTCACCCAGGGTTATCCAAGTAAGCTGTCTCTTGATGACTGCCATATTGGTGCTATCTGTAAGGCCGCAAACCGCGGT
GACTTGCTGGCCTGCGAAGTGATTGAACATGTTGGTCGCTACTTGGGGAAAGCCATTGCTATCACCATAAACTTATTCAA
CCCACAAAAAGTGGTGATTGCCGGTGAAATTATTGAAGCCGAGAAAATCCTACTACCCGCCATTCAGGGTTGCATTAATA
CGCAAGTTTTGAAAAACTTCCGCCAAAACCTGCCGATAGTGACATCACAACTTAACCACCAGTCGGCTATCGGCGCTTTC
GCACTGGCTAAGCGCGCTATGCTCAATGGTGTCTTGCTGCAACGTTTGCTAGAAACTCACCCGTAG

Upstream 100 bases:

>100_bases
GCCATTGGCGTGGATAAACAGTTAGGAAGTATTGAAGTCGGCAAAGTTGCCAACCTGACTGCCTTTACCCGCGATTATAA
AATCACTAAAACCATCGTTA

Downstream 100 bases:

>100_bases
GTTGAAAGAAACTGTCATGGTCACAGCCATGTTATAGTGACCTATTGCCGCGCTAAATGAGTAATATAAACAATGACAAT
CAAAAGCGTTATTTGCGATA

Product: N-acetylglucosamine regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MATRFYHKRVTLLMSTGGQAQIGNVDLVKQLNGAVVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQ
QASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLREL
IAIAVILPGLVEQSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAG
IIVNSQIFLGSNGNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRG
DLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAF
ALAKRAMLNGVLLQRLLETHP

Sequences:

>Translated_421_residues
MATRFYHKRVTLLMSTGGQAQIGNVDLVKQLNGAVVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQ
QASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLREL
IAIAVILPGLVEQSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAG
IIVNSQIFLGSNGNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRG
DLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAF
ALAKRAMLNGVLLQRLLETHP
>Mature_420_residues
ATRFYHKRVTLLMSTGGQAQIGNVDLVKQLNGAVVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQQ
ASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELI
AIAVILPGLVEQSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGI
IVNSQIFLGSNGNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRGD
LLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFA
LAKRAMLNGVLLQRLLETHP

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=302, Percent_Identity=23.841059602649, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI298566325, Length=302, Percent_Identity=23.841059602649, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI4885285, Length=302, Percent_Identity=23.841059602649, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI190014632, Length=302, Percent_Identity=23.841059602649, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786891, Length=405, Percent_Identity=77.7777777777778, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=400, Percent_Identity=40, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87082127, Length=332, Percent_Identity=21.3855421686747, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790522, Length=296, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=22.7941176470588, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082230, Length=267, Percent_Identity=26.2172284644195, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 46242; Mature: 46111

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRFYHKRVTLLMSTGGQAQIGNVDLVKQLNGAVVYRLIDQQGPISRIQIADLSQLAPA
CCCCHHHHEEEEEEECCCCCEECCHHHHHHCCCEEEEEEECCCCCCCEEEECCHHHCCCH
SVTKITRQLLERGLIKEVDQQASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEEECCC
KSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVEQSKGIVRY
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
MPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAG
CCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCE
IIVNSQIFLGSNGNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYP
EEEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
SKLSLDDCHIGAICKAANRGDLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEA
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECHHHH
EKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVLLQRLLETH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C
>Mature Secondary Structure 
ATRFYHKRVTLLMSTGGQAQIGNVDLVKQLNGAVVYRLIDQQGPISRIQIADLSQLAPA
CCCHHHHEEEEEEECCCCCEECCHHHHHHCCCEEEEEEECCCCCCCEEEECCHHHCCCH
SVTKITRQLLERGLIKEVDQQASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEEECCC
KSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVEQSKGIVRY
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
MPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAG
CCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCE
IIVNSQIFLGSNGNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYP
EEEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
SKLSLDDCHIGAICKAANRGDLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEA
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECHHHH
EKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVLLQRLLETH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]