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The map label for this gene is crcB1

Identifier: 108811245

GI number: 108811245

Start: 1243729

End: 1244112

Strand: Reverse

Name: crcB1

Synonym: YPN_1081

Alternate gene names: 108811245

Gene position: 1244112-1243729 (Counterclockwise)

Preceding gene: 108811247

Following gene: 108811243

Centisome position: 27.44

GC content: 46.88

Gene sequence:

>384_bases
ATGTTTAATACATTACTTGCAGTGTTTATTGGTGGCGGTGTGGGCAGCATGGCCCGTTGGTTGGTCAGTTTGAAGTTAAA
CAGTGCATCGGCTCACTTACCGGTAGGTACGCTTATTGTCAACCTGGTCGGTGCCTTTATTATTGGCCTGACACTGGCGT
TTTTTAGCCGAATGACTCATATTGATCCCGTTTGGAAGCTACTGATTACCACCGGTTTTTGTGGGGGCCTCACGACGTTC
TCCACCTTTTCTGTCGAAGTGGTCTATCTAATCCAAGAGGGAAAATTAGCGTGGGCTGCCGGAACAATTTTGCTCAATGT
GGCGGGTTCACTGGCAATGACGATGCTGGCTTTTATATTGGTCAATAACTTTGCCAGCCAATAA

Upstream 100 bases:

>100_bases
TTCTCATTAGGGTACGTAGGGCTACCAACGAGCCTTTCTGAAAAGATTTACGGGTAAACAAAACGCCCCAATGGTCAGTA
TCTGTTAGAGAAAAGTGCCT

Downstream 100 bases:

>100_bases
TGGCTAGTGGCCTATGATTAAACACTTCAAGGAGTGAATAGCGTGGCTATGGTGTTTATTCAGTAGAAAATAGTGCTACT
AATAATATCGCCTTAATGTT

Product: camphor resistance protein CrcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MFNTLLAVFIGGGVGSMARWLVSLKLNSASAHLPVGTLIVNLVGAFIIGLTLAFFSRMTHIDPVWKLLITTGFCGGLTTF
STFSVEVVYLIQEGKLAWAAGTILLNVAGSLAMTMLAFILVNNFASQ

Sequences:

>Translated_127_residues
MFNTLLAVFIGGGVGSMARWLVSLKLNSASAHLPVGTLIVNLVGAFIIGLTLAFFSRMTHIDPVWKLLITTGFCGGLTTF
STFSVEVVYLIQEGKLAWAAGTILLNVAGSLAMTMLAFILVNNFASQ
>Mature_127_residues
MFNTLLAVFIGGGVGSMARWLVSLKLNSASAHLPVGTLIVNLVGAFIIGLTLAFFSRMTHIDPVWKLLITTGFCGGLTTF
STFSVEVVYLIQEGKLAWAAGTILLNVAGSLAMTMLAFILVNNFASQ

Specific function: Not Known. Overproduction Leads To Camphor Resistance And Chromosome Condensation; Deletion Increases Sensibility To Nucleoid Decondensation. Probably Interacts With The Heat-Shock Protein Cspe, Possibly Providing A Way To Anchor The Chromosome To The Mem

COG id: COG0239

COG function: function code D; Integral membrane protein possibly involved in chromosome condensation

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CrcB family

Homologues:

Organism=Escherichia coli, GI1786842, Length=120, Percent_Identity=65, Blast_Score=158, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CRCB1_YERPE (Q8ZDH2)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AH0316
- RefSeq:   NP_668494.1
- RefSeq:   NP_992487.1
- RefSeq:   YP_002347552.1
- GeneID:   1146115
- GeneID:   1175425
- GeneID:   2764513
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2596
- KEGG:   ypk:y1168
- KEGG:   ypm:YP_1118
- HOGENOM:   HBG753179
- OMA:   IASHPEW
- ProtClustDB:   PRK14196
- BioCyc:   YPES187410:Y1168-MONOMER
- BioCyc:   YPES214092:YPO2596-MONOMER
- HAMAP:   MF_00454
- InterPro:   IPR003691
- TIGRFAMs:   TIGR00494

Pfam domain/function: PF02537 CRCB

EC number: NA

Molecular weight: Translated: 13483; Mature: 13483

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf7331e4)-; HASH(0xe3e7e94)-; HASH(0xe3e79a8)-; HASH(0xf41c464)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNTLLAVFIGGGVGSMARWLVSLKLNSASAHLPVGTLIVNLVGAFIIGLTLAFFSRMTH
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDPVWKLLITTGFCGGLTTFSTFSVEVVYLIQEGKLAWAAGTILLNVAGSLAMTMLAFIL
CCHHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHH
VNNFASQ
HHHHCCH
>Mature Secondary Structure
MFNTLLAVFIGGGVGSMARWLVSLKLNSASAHLPVGTLIVNLVGAFIIGLTLAFFSRMTH
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDPVWKLLITTGFCGGLTTFSTFSVEVVYLIQEGKLAWAAGTILLNVAGSLAMTMLAFIL
CCHHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHH
VNNFASQ
HHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430