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The map label for this gene is lpxH [H]

Identifier: 108811180

GI number: 108811180

Start: 1174207

End: 1174929

Strand: Reverse

Name: lpxH [H]

Synonym: YPN_1015

Alternate gene names: 108811180

Gene position: 1174929-1174207 (Counterclockwise)

Preceding gene: 108811181

Following gene: 108811179

Centisome position: 25.91

GC content: 47.03

Gene sequence:

>723_bases
ATGAGCACGCTTTTTATTGCAGATCTGCATCTCAGCGTTCAGGAACCGGCAATCACTGCCGGTTTTCTGCATTTTATACA
GCGTGAGGCTATTCATGCTGATGCTTTATATATTCTGGGTGATCTGTTCGAATCCTGGATTGGTGATGACGACCCCGAGC
CACTGTATCGGCAGGTTGCTGCTGCGCTGAAATCACTCCAACAACAGGGGGTGCCCTGTTATTTTATCCACGGGAACCGC
GATTTTCTGCTCGGTAAACGTTTTGCTGAAGAAAGCGGCATGGTCTTGCTGCCGGAAGAGAACGTTGTTGAATTATATGG
CCGTAAAATCCTTATTTTACATGGTGATACTCTGTGTACGGATGATACCGATTACCAGCATTTTCGTAAAAAGGTCCATA
ATCCGCTGATTCAAAAATTATTTTTGTGGATCCCTCTGCGCCTGCGTCTGCGTATTGCGGCCTATATGCGGAATAAGAGC
CAGCAGAATAATAGCGGTAAATCAGAACGCATTATGGATGTGAATTCAAAAGCGGTAATTGATGCTTTCCTGCGCCATGA
CGTCAGTTGGATGATCCATGGGCATACGCACCGGCCAGCCATCCATAGCGTAGAATTGCCGATGGTAACAGCACATCGGG
TAGTGCTGGGGGCCTGGCATGTCGAAGGTTCAATGGTCAAAGTTACGGCAGATAACGTCGAGCTAATTACATTCCCGTTT
TAA

Upstream 100 bases:

>100_bases
ATCAAAAATGTTGCGACGGGCCGCAGTGGCATGCATCAAGATGTGCCAAAAGAAGATGTGATCATCAAAAGCGTCACTAT
TAGCGAGTAATGACGGCTTA

Downstream 100 bases:

>100_bases
CATCCATTTCTACGCAATAACCTCGATTACCACACAGTAACCTCGATTACCACGCGATAACCTTGATTACCAAGCAATCA
CCCGCTCATGACGAATAACA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNR
DFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKS
QQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Sequences:

>Translated_240_residues
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNR
DFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKS
QQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
>Mature_239_residues
STLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRD
FLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQ
QNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=240, Percent_Identity=70, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 27444; Mature: 27313

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVA
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCT
HHHHHHHHCCCCEEEEECCCCEEHHHHHHCCCCEEEECCCCHHHHCCCEEEEEECCEEEC
DDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
DAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
HHHHHCCCEEEEECCCCCCCCEEECCCHHHHHEEEEEEEEECCCEEEEEECCEEEEEECC
>Mature Secondary Structure 
STLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVA
CEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCT
HHHHHHHHCCCCEEEEECCCCEEHHHHHHCCCCEEEECCCCHHHHCCCEEEEEECCEEEC
DDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
DAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
HHHHHCCCEEEEECCCCCCCCEEECCCHHHHHEEEEEEEEECCCEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA