BacMap

Definition	Yersinia pestis Nepal516, complete genome.
Accession	NC_008149
Length	4,534,590

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The map label for this gene is ybbO [H]

Identifier: 108811173

GI number: 108811173

Start: 1166691

End: 1167467

Strand: Reverse

Name: ybbO [H]

Synonym: YPN_1008

Alternate gene names: 108811173

Gene position: 1167467-1166691 (Counterclockwise)

Preceding gene: 108811174

Following gene: 108811172

Centisome position: 25.75

GC content: 52.64

Gene sequence:

>777_bases
ATGCAAAAAGCAGTATTGATTACCGGCTGTTCCAGTGGAATTGGTCTGGTAGCGGCACAAGATTTAAAAAACAGAGGTTA
TCGCGTGCTGGCCGCCTGCCGCAAACCTGACGATGTCGCCAAAATGGTGCAGTTAGGTCTGGAAGGTATTGAACTGGATT
TGGATGACAGCGCCAGTGTCGAACGCGCTGCGGCACAGGTTATCGAACTGACGGGTGGGCGGTTATATGGCCTGTTTAAT
AACGGCGGTTTTGGTCTGTACGGTTCACTGCACACCATTTCTCGCCAACAGTTGGAAAAGCAGTTTTCGACTAATCTGTT
TGGCACCCACCAACTGACACAGTTACTGCTACCCGCAATGTTGCCTCACGGTGAGGGGCGAATTATTCAAACCAGCTCAG
TGATGGGGTTGGTTTCAACGGCGGGGCGCGGTGCCTACGCCGCCAGTAAATATGCGCTGGAGGCCTGGTCTGATGCCCTG
CGAATGGAGCTACAGAGTAGTGGTATTCACGTCAGCCTGATTGAACCTGGTCCAATCAGCACCCATTTCACCCAAAATGT
GAATCAGGCAGAGGCCGATAAGCCGGTCAATAACCCAGGGATCGCCAAGCGATTTACACTGCCACCGGAAGCCATATTAC
CCAAATTGCGTCATGCGCTGGAAAGCCCACGCCCGCAATTGCGTTATCCGGTCACGATGGTGGCCCATGCGTTGACCCTA
CTACGTCGTCTATTACCTGGCCGGATGCTAGATAGAGTCCTGCGCGGTAATAGTTAA

Upstream 100 bases:

>100_bases
GTACATGCAACTTGAAGTATGACGGGTATATTTATTCAAGACTAACCTTGCTCAGTTAACCATTTGTTTAAGCAAATAGA
TTCATTCATTAGGTAAAGTT

Downstream 100 bases:

>100_bases
GCCAGATCATTGACTAAGGGTTGAAGCAAGGCAATCCGCCCCCATCTATCGTTAAAACGGATGAGAGAAATAATTCATGC
TAACACCTACAACGATTGAA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MQKAVLITGCSSGIGLVAAQDLKNRGYRVLAACRKPDDVAKMVQLGLEGIELDLDDSASVERAAAQVIELTGGRLYGLFN
NGGFGLYGSLHTISRQQLEKQFSTNLFGTHQLTQLLLPAMLPHGEGRIIQTSSVMGLVSTAGRGAYAASKYALEAWSDAL
RMELQSSGIHVSLIEPGPISTHFTQNVNQAEADKPVNNPGIAKRFTLPPEAILPKLRHALESPRPQLRYPVTMVAHALTL
LRRLLPGRMLDRVLRGNS

Sequences:

>Translated_258_residues
MQKAVLITGCSSGIGLVAAQDLKNRGYRVLAACRKPDDVAKMVQLGLEGIELDLDDSASVERAAAQVIELTGGRLYGLFN
NGGFGLYGSLHTISRQQLEKQFSTNLFGTHQLTQLLLPAMLPHGEGRIIQTSSVMGLVSTAGRGAYAASKYALEAWSDAL
RMELQSSGIHVSLIEPGPISTHFTQNVNQAEADKPVNNPGIAKRFTLPPEAILPKLRHALESPRPQLRYPVTMVAHALTL
LRRLLPGRMLDRVLRGNS
>Mature_258_residues
MQKAVLITGCSSGIGLVAAQDLKNRGYRVLAACRKPDDVAKMVQLGLEGIELDLDDSASVERAAAQVIELTGGRLYGLFN
NGGFGLYGSLHTISRQQLEKQFSTNLFGTHQLTQLLLPAMLPHGEGRIIQTSSVMGLVSTAGRGAYAASKYALEAWSDAL
RMELQSSGIHVSLIEPGPISTHFTQNVNQAEADKPVNNPGIAKRFTLPPEAILPKLRHALESPRPQLRYPVTMVAHALTL
LRRLLPGRMLDRVLRGNS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI150247226, Length=280, Percent_Identity=32.5, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI7657478, Length=271, Percent_Identity=33.210332103321, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI223718074, Length=258, Percent_Identity=32.1705426356589, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=34.3589743589744, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=34.3589743589744, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=34.3589743589744, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=34.3589743589744, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI19743808, Length=283, Percent_Identity=32.8621908127208, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI50726952, Length=285, Percent_Identity=32.6315789473684, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI22507405, Length=185, Percent_Identity=37.2972972972973, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=32.2115384615385, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=30.1980198019802, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI119392083, Length=203, Percent_Identity=31.5270935960591, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI142976729, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504503, Length=197, Percent_Identity=26.3959390862944, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32483357, Length=190, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40254992, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=256, Percent_Identity=68.359375, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=30.6451612903226, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082100, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787820, Length=216, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI2367365, Length=182, Percent_Identity=29.6703296703297, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=285, Percent_Identity=27.719298245614, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17557780, Length=290, Percent_Identity=26.551724137931, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=31.25, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=289, Percent_Identity=25.2595155709343, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=289, Percent_Identity=25.2595155709343, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=195, Percent_Identity=29.7435897435897, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559962, Length=205, Percent_Identity=31.219512195122, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=244, Percent_Identity=25, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=268, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=33.5051546391753, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24651139, Length=195, Percent_Identity=33.8461538461538, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21356301, Length=202, Percent_Identity=31.1881188118812, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24643142, Length=182, Percent_Identity=29.1208791208791, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581726, Length=227, Percent_Identity=26.431718061674, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19922066, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553409, Length=205, Percent_Identity=28.2926829268293, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647948, Length=205, Percent_Identity=28.2926829268293, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647946, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24639444, Length=185, Percent_Identity=28.6486486486486, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=26.530612244898, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27942; Mature: 27942

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKAVLITGCSSGIGLVAAQDLKNRGYRVLAACRKPDDVAKMVQLGLEGIELDLDDSASV
CCCEEEEEECCCCCCCEEHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEECCCCCCHH
ERAAAQVIELTGGRLYGLFNNGGFGLYGSLHTISRQQLEKQFSTNLFGTHQLTQLLLPAM
HHHHHHHHHHCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LPHGEGRIIQTSSVMGLVSTAGRGAYAASKYALEAWSDALRMELQSSGIHVSLIEPGPIS
CCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
THFTQNVNQAEADKPVNNPGIAKRFTLPPEAILPKLRHALESPRPQLRYPVTMVAHALTL
HHHHCCCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LRRLLPGRMLDRVLRGNS
HHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MQKAVLITGCSSGIGLVAAQDLKNRGYRVLAACRKPDDVAKMVQLGLEGIELDLDDSASV
CCCEEEEEECCCCCCCEEHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEECCCCCCHH
ERAAAQVIELTGGRLYGLFNNGGFGLYGSLHTISRQQLEKQFSTNLFGTHQLTQLLLPAM
HHHHHHHHHHCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LPHGEGRIIQTSSVMGLVSTAGRGAYAASKYALEAWSDALRMELQSSGIHVSLIEPGPIS
CCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
THFTQNVNQAEADKPVNNPGIAKRFTLPPEAILPKLRHALESPRPQLRYPVTMVAHALTL
HHHHCCCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LRRLLPGRMLDRVLRGNS
HHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]