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The map label for this gene is bcd [H]

Identifier: 108798036

GI number: 108798036

Start: 1158707

End: 1159873

Strand: Reverse

Name: bcd [H]

Synonym: Mmcs_1063

Alternate gene names: 108798036

Gene position: 1159873-1158707 (Counterclockwise)

Preceding gene: 108798037

Following gene: 108798035

Centisome position: 20.33

GC content: 68.04

Gene sequence:

>1167_bases
ATGGATCTCTTTGGCCTCGACGACGACGAACGCGTGATCGCCGAGACAGCGGCCGCGTTCGCCGAGAAGCGCCTCGCCCC
ATACGCATCGGAGTGGGATGAGAGCCACCACTTCCCTACCGACGTGTTGCGGGAGGCGGCCGAACTCGGCATGGCGGCGA
TCTACTGCCGTGAGGACGTCGGCGGCAGCGGGCTGCGGCGCGTCGATGCCGTGCGCATCTTCGAACAGCTGTCCGCGGCC
GACCCGGCCATCGCGGCGTTCCTGTCGATCCACAACATGTGCGCATGGATGGTCGACACCTACGGCTCCGAGGAGCAGCG
CAAGACGTGGGTGCCGCGGCTGGCGTCGATGGAGAGCATCGCGAGCTACTGCCTCACCGAACCGGGTGCGGGGTCGGACG
CGAGTGCGTTGCGCACCAAGGCCGTTCGGGAGGGCGACCACTTCGTCCTCGACGGGGTGAAGCAGTTCATCTCGGGTGCG
GGCAGTTCCGACGTGTACGTGGTGATGGCCCGCACCGGCAGTGACGGACCGCGCGGCATCTCGGCGTTCGTGGTCGAGAA
GGACACGCCCGGTGTGAGTTTCGGCGCCCAGGAACAGAAGATGGGGTGGAACGCGCAGCCCACGGCGCAGGTCGTGTTCG
AGGGCGCCCGGGTGCCGGCCGAGAACATGCTCGGTGGCACCGACGCCGAGGGCAGCGGTTTCGGCATCGCGATGAACGGC
CTCAACGGCGGGCGCCTCAACATCGCCGCCTGCTCGCTGGGCGGTGCGCAGACGGCCTACGAGAAGGCGGCCGCCTATCT
GGCCGACCGGCAGGCCTTCGGCGCGTCGTTGCTCGACGAGCCGACCATCCGGTTCACCCTGGCCGATATGGCCACCGCCC
TGCAGACGTCGCGCACGTTGTTGTGGCGGGCGGCCGGCGCACTCGACGAGAACCACCCGGACAAGGTGGAGTTGTGCGCG
ATGGCGAAGCGCTATGTCACGGACGCCTGTTACGAGGTGGCCGATCAGGCGCTCCAATTGCACGGCGGCTACGGCTATCT
GCGCGAGTACGGGATCGAGAAGATCGTCCGCGATCTGCGGGTCCACCGGATCCTCGAGGGCAGCAACGAGATCATGCGCG
TGGTCATCGGGCGGGCAGCCGCTGCGAGGGCGCGGACATCGGCTTAA

Upstream 100 bases:

>100_bases
CTACACCAAGACCAAGACCGTCACGCAGCGCTGGCCGTCGGGCATCAAGGATGGCGCCGAATTCGTCATCCCCACGATGA
AGTAGAGCTGAAGTATCCCC

Downstream 100 bases:

>100_bases
GGAGTTCAGACAGTGACGACGATTGCGTTCTTCGGCCTGGGCCACATGGGCGGTCCGATGGCGGCCAACCTGGCCAAGGC
GGGGCACACCGTGCGGGGTT

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MDLFGLDDDERVIAETAAAFAEKRLAPYASEWDESHHFPTDVLREAAELGMAAIYCREDVGGSGLRRVDAVRIFEQLSAA
DPAIAAFLSIHNMCAWMVDTYGSEEQRKTWVPRLASMESIASYCLTEPGAGSDASALRTKAVREGDHFVLDGVKQFISGA
GSSDVYVVMARTGSDGPRGISAFVVEKDTPGVSFGAQEQKMGWNAQPTAQVVFEGARVPAENMLGGTDAEGSGFGIAMNG
LNGGRLNIAACSLGGAQTAYEKAAAYLADRQAFGASLLDEPTIRFTLADMATALQTSRTLLWRAAGALDENHPDKVELCA
MAKRYVTDACYEVADQALQLHGGYGYLREYGIEKIVRDLRVHRILEGSNEIMRVVIGRAAAARARTSA

Sequences:

>Translated_388_residues
MDLFGLDDDERVIAETAAAFAEKRLAPYASEWDESHHFPTDVLREAAELGMAAIYCREDVGGSGLRRVDAVRIFEQLSAA
DPAIAAFLSIHNMCAWMVDTYGSEEQRKTWVPRLASMESIASYCLTEPGAGSDASALRTKAVREGDHFVLDGVKQFISGA
GSSDVYVVMARTGSDGPRGISAFVVEKDTPGVSFGAQEQKMGWNAQPTAQVVFEGARVPAENMLGGTDAEGSGFGIAMNG
LNGGRLNIAACSLGGAQTAYEKAAAYLADRQAFGASLLDEPTIRFTLADMATALQTSRTLLWRAAGALDENHPDKVELCA
MAKRYVTDACYEVADQALQLHGGYGYLREYGIEKIVRDLRVHRILEGSNEIMRVVIGRAAAARARTSA
>Mature_388_residues
MDLFGLDDDERVIAETAAAFAEKRLAPYASEWDESHHFPTDVLREAAELGMAAIYCREDVGGSGLRRVDAVRIFEQLSAA
DPAIAAFLSIHNMCAWMVDTYGSEEQRKTWVPRLASMESIASYCLTEPGAGSDASALRTKAVREGDHFVLDGVKQFISGA
GSSDVYVVMARTGSDGPRGISAFVVEKDTPGVSFGAQEQKMGWNAQPTAQVVFEGARVPAENMLGGTDAEGSGFGIAMNG
LNGGRLNIAACSLGGAQTAYEKAAAYLADRQAFGASLLDEPTIRFTLADMATALQTSRTLLWRAAGALDENHPDKVELCA
MAKRYVTDACYEVADQALQLHGGYGYLREYGIEKIVRDLRVHRILEGSNEIMRVVIGRAAAARARTSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=52.9255319148936, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=38.8739946380697, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=34.1333333333333, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=32.4538258575198, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=32.4538258575198, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=33.3333333333333, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=34.6153846153846, Blast_Score=214, Evalue=8e-56,
Organism=Homo sapiens, GI76496475, Length=338, Percent_Identity=34.6153846153846, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI21361497, Length=357, Percent_Identity=35.0140056022409, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=32.3684210526316, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=33.2361516034985, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=29.7368421052632, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=29.7222222222222, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI38505218, Length=290, Percent_Identity=29.3103448275862, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=28.6713286713287, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=28.6713286713287, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=29.9212598425197, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=26.6149870801034, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082384, Length=271, Percent_Identity=28.4132841328413, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=49.7340425531915, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=36.0526315789474, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=34.8284960422164, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=33.8666666666667, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI71985184, Length=360, Percent_Identity=34.1666666666667, Blast_Score=217, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=34.2857142857143, Blast_Score=215, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=32.2666666666667, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=30.9895833333333, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=39.2241379310345, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=32.6086956521739, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17551932, Length=384, Percent_Identity=29.1666666666667, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=30.5483028720627, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=297, Percent_Identity=31.986531986532, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=29.1005291005291, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=27.5757575757576, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=28.3950617283951, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=334, Percent_Identity=26.9461077844311, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=334, Percent_Identity=26.9461077844311, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=34.6666666666667, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=36.436170212766, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=34.7368421052632, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=37.5661375661376, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=33.7278106508876, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=33.2460732984293, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=26.6490765171504, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41692; Mature: 41692

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFGLDDDERVIAETAAAFAEKRLAPYASEWDESHHFPTDVLREAAELGMAAIYCREDV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCEEEEEECCC
GGSGLRRVDAVRIFEQLSAADPAIAAFLSIHNMCAWMVDTYGSEEQRKTWVPRLASMESI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ASYCLTEPGAGSDASALRTKAVREGDHFVLDGVKQFISGAGSSDVYVVMARTGSDGPRGI
HHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
SAFVVEKDTPGVSFGAQEQKMGWNAQPTAQVVFEGARVPAENMLGGTDAEGSGFGIAMNG
EEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEEEC
LNGGRLNIAACSLGGAQTAYEKAAAYLADRQAFGASLLDEPTIRFTLADMATALQTSRTL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHHHHH
LWRAAGALDENHPDKVELCAMAKRYVTDACYEVADQALQLHGGYGYLREYGIEKIVRDLR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VHRILEGSNEIMRVVIGRAAAARARTSA
HHHHHCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLFGLDDDERVIAETAAAFAEKRLAPYASEWDESHHFPTDVLREAAELGMAAIYCREDV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCEEEEEECCC
GGSGLRRVDAVRIFEQLSAADPAIAAFLSIHNMCAWMVDTYGSEEQRKTWVPRLASMESI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ASYCLTEPGAGSDASALRTKAVREGDHFVLDGVKQFISGAGSSDVYVVMARTGSDGPRGI
HHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
SAFVVEKDTPGVSFGAQEQKMGWNAQPTAQVVFEGARVPAENMLGGTDAEGSGFGIAMNG
EEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEEEC
LNGGRLNIAACSLGGAQTAYEKAAAYLADRQAFGASLLDEPTIRFTLADMATALQTSRTL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHHHHH
LWRAAGALDENHPDKVELCAMAKRYVTDACYEVADQALQLHGGYGYLREYGIEKIVRDLR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VHRILEGSNEIMRVVIGRAAAARARTSA
HHHHHCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]