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The map label for this gene is pkn1 [H]

Identifier: 108797997

GI number: 108797997

Start: 1126601

End: 1127473

Strand: Direct

Name: pkn1 [H]

Synonym: Mmcs_1024

Alternate gene names: 108797997

Gene position: 1126601-1127473 (Clockwise)

Preceding gene: 108797996

Following gene: 108797998

Centisome position: 19.75

GC content: 71.82

Gene sequence:

>873_bases
ATGCTGACCGAGCTGGTCGAACTGCCGGGCGGCACCTTCCGGATGGGCTCCACGCAGTTCTATCCGGAGGAAGTGCCGGT
GCACACGGTGACCGTCGCCGACTTCGCGATCGAGCGCCATCCCGTCACCAACGCACAGTTCGCCGAGTTCGTCGACGCCA
CCGGCTACGTCACGATCGCCGAACAGGCCCTCGATCCCGCGCTGTATCCAGGTGTGCCGCCGGCCGATCTGGTGCCGGGC
GCGCTGGTGTTCCAGCCGACCGCGGGGCCGGTCGACCTGCGGGACTGGCGGCAGTGGTGGACGTGGTCGCCGGGCGCGTG
CTGGCGTCACCCGCTCGGCCCGGAGTCGAGCTGGCACGACCGTCCGGACCACCCCGTCGTCCAGGTCGCCTACCCGGACG
CCGCCGCCTACGCGAAATGGGCCGGCCGGCGACTGCCCACGGAGGCGCAGTGGGAATACGCCGCACACGCGGGCGCGGCC
ACCACCTATCCGTGGGGTGACGACCCGCAACCGGGCGGACGGCTGATGGCCAACACCTGGCAGGGCCGGTTCCCGTACCG
CAACGACGGTGCGCTCGGCTGGGTCGGCACGTCGCCGGTGGGCACGTTCCCCGCCAACGGCTTCGGCCTGGTCGACATGA
TCGGCAACGTGTGGGAGTGGACGACGACGCGGTTCTCGGCGCACCACCGTCCCGACGGCGCCGTCGAATCGTGCTGCGGG
CCCGCCGATCCCGATCCGTCGGTCAACCAGGCGCTCAAGGGCGGCTCGCACCTGTGCGCGCCCGAGTACTGCCACCGGTA
CCGGGCCGCCGCGCGGTCACCGCAGTCACAGGACAGCGCGACGACGCACATCGGGTTCCGCTGCGTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCCAGGTCTCGTTCGACGTCTCCGGCAAGCCCTACCTCGACCTGGAACGCGAGTTCGCCCGGGCCTTCGCGAAGGAC
TGACCCTCTACGCTGAAGAG

Downstream 100 bases:

>100_bases
GCTGCGGAGGCTGACCTGCGGCGATTTGGTTCTCTGCAGGTCCTCACCTAGAATCAAACGGTTGCCTTGGGCAGACCTCG
GCCGATCCGCAATGCTTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLTELVELPGGTFRMGSTQFYPEEVPVHTVTVADFAIERHPVTNAQFAEFVDATGYVTIAEQALDPALYPGVPPADLVPG
ALVFQPTAGPVDLRDWRQWWTWSPGACWRHPLGPESSWHDRPDHPVVQVAYPDAAAYAKWAGRRLPTEAQWEYAAHAGAA
TTYPWGDDPQPGGRLMANTWQGRFPYRNDGALGWVGTSPVGTFPANGFGLVDMIGNVWEWTTTRFSAHHRPDGAVESCCG
PADPDPSVNQALKGGSHLCAPEYCHRYRAAARSPQSQDSATTHIGFRCVA

Sequences:

>Translated_290_residues
MLTELVELPGGTFRMGSTQFYPEEVPVHTVTVADFAIERHPVTNAQFAEFVDATGYVTIAEQALDPALYPGVPPADLVPG
ALVFQPTAGPVDLRDWRQWWTWSPGACWRHPLGPESSWHDRPDHPVVQVAYPDAAAYAKWAGRRLPTEAQWEYAAHAGAA
TTYPWGDDPQPGGRLMANTWQGRFPYRNDGALGWVGTSPVGTFPANGFGLVDMIGNVWEWTTTRFSAHHRPDGAVESCCG
PADPDPSVNQALKGGSHLCAPEYCHRYRAAARSPQSQDSATTHIGFRCVA
>Mature_290_residues
MLTELVELPGGTFRMGSTQFYPEEVPVHTVTVADFAIERHPVTNAQFAEFVDATGYVTIAEQALDPALYPGVPPADLVPG
ALVFQPTAGPVDLRDWRQWWTWSPGACWRHPLGPESSWHDRPDHPVVQVAYPDAAAYAKWAGRRLPTEAQWEYAAHAGAA
TTYPWGDDPQPGGRLMANTWQGRFPYRNDGALGWVGTSPVGTFPANGFGLVDMIGNVWEWTTTRFSAHHRPDGAVESCCG
PADPDPSVNQALKGGSHLCAPEYCHRYRAAARSPQSQDSATTHIGFRCVA

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=292, Percent_Identity=41.7808219178082, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI257470975, Length=292, Percent_Identity=40.4109589041096, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI257470977, Length=292, Percent_Identity=40.0684931506849, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI194248088, Length=292, Percent_Identity=36.986301369863, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI194248087, Length=292, Percent_Identity=35.6164383561644, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI226437577, Length=194, Percent_Identity=39.6907216494845, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI194248090, Length=261, Percent_Identity=35.632183908046, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI20130397, Length=298, Percent_Identity=37.248322147651, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31693; Mature: 31693

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTELVELPGGTFRMGSTQFYPEEVPVHTVTVADFAIERHPVTNAQFAEFVDATGYVTIA
CCCCHHHCCCCEEECCCCCCCCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHCCCCEEEEH
EQALDPALYPGVPPADLVPGALVFQPTAGPVDLRDWRQWWTWSPGACWRHPLGPESSWHD
HHHCCCHHCCCCCCHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RPDHPVVQVAYPDAAAYAKWAGRRLPTEAQWEYAAHAGAATTYPWGDDPQPGGRLMANTW
CCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECC
QGRFPYRNDGALGWVGTSPVGTFPANGFGLVDMIGNVWEWTTTRFSAHHRPDGAVESCCG
CCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCHHHHHCCC
PADPDPSVNQALKGGSHLCAPEYCHRYRAAARSPQSQDSATTHIGFRCVA
CCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MLTELVELPGGTFRMGSTQFYPEEVPVHTVTVADFAIERHPVTNAQFAEFVDATGYVTIA
CCCCHHHCCCCEEECCCCCCCCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHCCCCEEEEH
EQALDPALYPGVPPADLVPGALVFQPTAGPVDLRDWRQWWTWSPGACWRHPLGPESSWHD
HHHCCCHHCCCCCCHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RPDHPVVQVAYPDAAAYAKWAGRRLPTEAQWEYAAHAGAATTYPWGDDPQPGGRLMANTW
CCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECC
QGRFPYRNDGALGWVGTSPVGTFPANGFGLVDMIGNVWEWTTTRFSAHHRPDGAVESCCG
CCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCHHHHHCCC
PADPDPSVNQALKGGSHLCAPEYCHRYRAAARSPQSQDSATTHIGFRCVA
CCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]