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The map label for this gene is hmp [H]

Identifier: 108797890

GI number: 108797890

Start: 1014217

End: 1015419

Strand: Direct

Name: hmp [H]

Synonym: Mmcs_0916

Alternate gene names: 108797890

Gene position: 1014217-1015419 (Clockwise)

Preceding gene: 108797889

Following gene: 108797891

Centisome position: 17.78

GC content: 70.74

Gene sequence:

>1203_bases
ATGACCGTCACCGCAAACGTTGCCGTCGGCGAAGAACTCGACCCGCAGCACGCGGAGATCATCACCGCCACGCTGCCGCT
CGTCGGCGCGCACATCGACGAGATCACGACGGTCTTCTACAGCCGGATGTTCGCCGCCCGCCCGGAACTGCTGCGCAACC
TGTTCAACCGGGGCAACCAGGCCCAGGGCGCTCAGCAGCGGGCGCTGGCCGCGTCGATCGCCACCTACGCGACCCACCTC
GTCGACCCGAACCTGCCGCATCCGGCCGAATTGCTGTCGCGGATCGGGCACAAGCACGCCTCGCTCGGGATCACCGCCGA
CCAGTACGAGATCGTGTACGAGCACCTGTTCGCCGCGATCGTCGAGGTGCTGGGCGCCGACACCGTCACCGCGCCGGTGG
CCGAGGCGTGGGACGCCGTCTACTGGATGATGGCGCGCACGCTGATCGAGCTGGAACGCCACCTCTACGCCGAGGCGGGC
GTCGATGACGGTGACGTCTACCGCCGCGCGCGGGTGGTCGCCCGCGAGGACGATCCGTCCGGCGCCGTCCTGCTGACCGT
GCGCTCGACCGCGCAGCCGTTCTCCGGCTTCCGGCCCGGCCAGTACGTGTCGGTGGGGGTGACGCTGCCCGACGGCGCCC
GCCAGCTGCGGCAGTACAGCCTGATCAACACCCCGGGCGGTAACGGCGACCTGACGTTCGCGGTGCGCCCGCTCGGTGAG
GTGTCGAACTGGATCCGCGCCAACGTGCGGGCCGGCGACGTCCTCGACGTCACCGTGCCGTTCGGTGACCTGCCCGACCC
CGAGCAGCACCACCGGCCGCTGGTATTGGTGTCCGCGGGCATCGGCATCACCCCGATGATCGGCATCCTCGAGCACCTGG
CCTCCGTCGCGCCCGCGACGAGCGTGCAGGTGTGGCACGCCGACCGGTCGGCAGCCACCCATCCGCTCAAGGACCGCCAG
CAGGAGCTCGTCGCCGCGCTGCCCGACGCCACGCTGGAGCTCTGGTACGAGGAGGCCGACGCGCACGCACGCCCGGGTCT
GCTGAACGTCGCCGATGTGGAGCTGCCCGAGGACGCGGAGGTGTACCTGTGCGGCGGCAACGGCTTCGTGCAGGCGGTGC
GCGCTCAGCTGCAGGAGCGCGGCGTGCCGAACGAGCGGCTGCACTGCGAGTTGTTCTCCCCGAACGACTGGCTGCTGGCC
TGA

Upstream 100 bases:

>100_bases
AACTCGACCGCTACACGATCACCGATCTGGCGGCCCCTGCACTTCCCCTGGTGTTCCTCGGAGCGCCGGTGAAGAACCCC
ACCGATGAAAGGACCCTCTG

Downstream 100 bases:

>100_bases
TCGACCGAATACGGACTGGCCCGCGACTGGTCGCACTGACCAGCGGTTTGGCGCCTGAGCGGGCCAGACTGTACTCTCTT
TAAGGCCCACGGCACGGCCT

Product: oxidoreductase FAD-binding region

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTVTANVAVGEELDPQHAEIITATLPLVGAHIDEITTVFYSRMFAARPELLRNLFNRGNQAQGAQQRALAASIATYATHL
VDPNLPHPAELLSRIGHKHASLGITADQYEIVYEHLFAAIVEVLGADTVTAPVAEAWDAVYWMMARTLIELERHLYAEAG
VDDGDVYRRARVVAREDDPSGAVLLTVRSTAQPFSGFRPGQYVSVGVTLPDGARQLRQYSLINTPGGNGDLTFAVRPLGE
VSNWIRANVRAGDVLDVTVPFGDLPDPEQHHRPLVLVSAGIGITPMIGILEHLASVAPATSVQVWHADRSAATHPLKDRQ
QELVAALPDATLELWYEEADAHARPGLLNVADVELPEDAEVYLCGGNGFVQAVRAQLQERGVPNERLHCELFSPNDWLLA

Sequences:

>Translated_400_residues
MTVTANVAVGEELDPQHAEIITATLPLVGAHIDEITTVFYSRMFAARPELLRNLFNRGNQAQGAQQRALAASIATYATHL
VDPNLPHPAELLSRIGHKHASLGITADQYEIVYEHLFAAIVEVLGADTVTAPVAEAWDAVYWMMARTLIELERHLYAEAG
VDDGDVYRRARVVAREDDPSGAVLLTVRSTAQPFSGFRPGQYVSVGVTLPDGARQLRQYSLINTPGGNGDLTFAVRPLGE
VSNWIRANVRAGDVLDVTVPFGDLPDPEQHHRPLVLVSAGIGITPMIGILEHLASVAPATSVQVWHADRSAATHPLKDRQ
QELVAALPDATLELWYEEADAHARPGLLNVADVELPEDAEVYLCGGNGFVQAVRAQLQERGVPNERLHCELFSPNDWLLA
>Mature_399_residues
TVTANVAVGEELDPQHAEIITATLPLVGAHIDEITTVFYSRMFAARPELLRNLFNRGNQAQGAQQRALAASIATYATHLV
DPNLPHPAELLSRIGHKHASLGITADQYEIVYEHLFAAIVEVLGADTVTAPVAEAWDAVYWMMARTLIELERHLYAEAGV
DDGDVYRRARVVAREDDPSGAVLLTVRSTAQPFSGFRPGQYVSVGVTLPDGARQLRQYSLINTPGGNGDLTFAVRPLGEV
SNWIRANVRAGDVLDVTVPFGDLPDPEQHHRPLVLVSAGIGITPMIGILEHLASVAPATSVQVWHADRSAATHPLKDRQQ
ELVAALPDATLELWYEEADAHARPGLLNVADVELPEDAEVYLCGGNGFVQAVRAQLQERGVPNERLHCELFSPNDWLLA

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=406, Percent_Identity=33.4975369458128, Blast_Score=195, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6321673, Length=398, Percent_Identity=31.1557788944724, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43528; Mature: 43396

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTANVAVGEELDPQHAEIITATLPLVGAHIDEITTVFYSRMFAARPELLRNLFNRGNQ
CEEEEEEEECCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
AQGAQQRALAASIATYATHLVDPNLPHPAELLSRIGHKHASLGITADQYEIVYEHLFAAI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
VEVLGADTVTAPVAEAWDAVYWMMARTLIELERHLYAEAGVDDGDVYRRARVVAREDDPS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCC
GAVLLTVRSTAQPFSGFRPGQYVSVGVTLPDGARQLRQYSLINTPGGNGDLTFAVRPLGE
CEEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCEECCCCCCEEEEEECCHHH
VSNWIRANVRAGDVLDVTVPFGDLPDPEQHHRPLVLVSAGIGITPMIGILEHLASVAPAT
HHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCC
SVQVWHADRSAATHPLKDRQQELVAALPDATLELWYEEADAHARPGLLNVADVELPEDAE
EEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCE
VYLCGGNGFVQAVRAQLQERGVPNERLHCELFSPNDWLLA
EEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TVTANVAVGEELDPQHAEIITATLPLVGAHIDEITTVFYSRMFAARPELLRNLFNRGNQ
EEEEEEEECCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
AQGAQQRALAASIATYATHLVDPNLPHPAELLSRIGHKHASLGITADQYEIVYEHLFAAI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
VEVLGADTVTAPVAEAWDAVYWMMARTLIELERHLYAEAGVDDGDVYRRARVVAREDDPS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCC
GAVLLTVRSTAQPFSGFRPGQYVSVGVTLPDGARQLRQYSLINTPGGNGDLTFAVRPLGE
CEEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCEECCCCCCEEEEEECCHHH
VSNWIRANVRAGDVLDVTVPFGDLPDPEQHHRPLVLVSAGIGITPMIGILEHLASVAPAT
HHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCC
SVQVWHADRSAATHPLKDRQQELVAALPDATLELWYEEADAHARPGLLNVADVELPEDAE
EEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCE
VYLCGGNGFVQAVRAQLQERGVPNERLHCELFSPNDWLLA
EEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14521231; 11481432 [H]